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Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activity

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dc.contributor.authorZanutto, Fabiana Volpe [UNESP]
dc.contributor.authorBoldrin, Paula Karina [UNESP]
dc.contributor.authorVaranda, Eliana Aparecida [UNESP]
dc.contributor.authorDe Souza, Samara Fernandes [UNESP]
dc.contributor.authorSano, Paulo Takeo
dc.contributor.authorVilegas, Wagner [UNESP]
dc.contributor.authorSantos, Lourdes Campaner dos [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-27T11:27:32Z
dc.date.available2014-05-27T11:27:32Z
dc.date.issued2013-01-01
dc.description.abstractA HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a. © 2013 by the authors.en
dc.description.affiliationDepartment of Organic Chemistry Institute of Chemistry UNESP - Sao Paulo State University, Araraquara CEP 14800-900, Sao Paulo
dc.description.affiliationDepartment of Biological Sciences Faculty of Pharmaceutical Sciences of Araraquara UNESP - Sao Paulo State University, Araraquara CEP 14801-902, Sao Paulo
dc.description.affiliationInstitute of Biosciences Sao Paulo University, Sao Paulo CEP 05508-900, Sao Paulo
dc.description.affiliationExperimental Campus of Sao Vicente UNESP - Sao Paulo State University, Sao Vicente CEP 11350-000, Sao Paulo
dc.description.affiliationUnespDepartment of Organic Chemistry Institute of Chemistry UNESP - Sao Paulo State University, Araraquara CEP 14800-900, Sao Paulo
dc.description.affiliationUnespDepartment of Biological Sciences Faculty of Pharmaceutical Sciences of Araraquara UNESP - Sao Paulo State University, Araraquara CEP 14801-902, Sao Paulo
dc.description.affiliationUnespExperimental Campus of Sao Vicente UNESP - Sao Paulo State University, Sao Vicente CEP 11350-000, Sao Paulo
dc.format.extent244-262
dc.identifierhttp://dx.doi.org/10.3390/molecules18010244
dc.identifier.citationMolecules, v. 18, n. 1, p. 244-262, 2013.
dc.identifier.doi10.3390/molecules18010244
dc.identifier.file2-s2.0-84872856447.pdf
dc.identifier.issn1420-3049
dc.identifier.lattes7927877224326837
dc.identifier.lattes3538253640602977
dc.identifier.orcid0000-0003-3032-2556
dc.identifier.scopus2-s2.0-84872856447
dc.identifier.scopus2-s2.0-84878734590
dc.identifier.urihttp://hdl.handle.net/11449/74289
dc.identifier.wosWOS:000314032900018
dc.language.isoeng
dc.relation.ispartofMolecules
dc.relation.ispartofjcr3.098
dc.relation.ispartofsjr0,855
dc.rights.accessRightsAcesso abertopt
dc.sourceScopus
dc.subjectFlavonoids
dc.subjectMutagenicity
dc.subjectNaphthopyranones
dc.subjectPaepalanthus
dc.titleCharacterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activityen
dc.typeArtigopt
dcterms.licensehttp://www.mdpi.com/about/openaccess
dspace.entity.typePublication
relation.isDepartmentOfPublication5004bcab-94af-4939-b980-091ae9d0a19e
relation.isDepartmentOfPublication.latestForDiscovery5004bcab-94af-4939-b980-091ae9d0a19e
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.author.lattes7927877224326837
unesp.author.lattes3538253640602977
unesp.author.orcid0000-0003-3032-2556[6]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, São Vicentept
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentCiências Biológicas - FCFpt
unesp.departmentCiências Biológicas - IBCLPpt
unesp.departmentQuímica Orgânica - IQARpt

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Araraquara - IQAR - Instituto de Química
Araraquara - FCF - Faculdade de Ciências Farmacêuticas
São Vicente - IBCLP - Instituto de Biociências