TROMBOSE VENOSA EXPERIMENTAL NA COBAIA: EFEITO DA HEPARINA E DE DROGAS QUE ALTERAM A FUNCAO PLAQUETARIA
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Thrombosis was induced in the jugular vein of guinea pigs by damage of the epithelium with a sclerosing solution. The effect of heparin, Dextran 70, acetylsalicylic acid, dipyridamole and phenylbutazone in preventing the development of the thrombus was investigated. Only heparin in high doses showed this effect.
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acetylsalicylic acid , dextran 70 , dipyridamole , heparin , phenylbutazone , animal experiment , blood and hemopoietic system , drug efficacy , guinea pig , jugular vein , thrombocyte aggregation , thrombosis , Animals , Anti-Inflammatory Agents , Anticoagulants , Aspirin , Blood Platelets , Dextrans , Dipyridamole , Drug Evaluation , Guinea Pigs , Heparin , Phenylbutazone , Thrombophlebitis
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Português
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Brazilian Journal of Medical and Biological Research, v. 10, n. 6, p. 369-378, 1977.
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