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The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor

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dc.contributor.authorSimoes, Luciana Senna
dc.contributor.authorCastro Sasahara, Tais Harumi de
dc.contributor.authorFavaron, Phelipe Oliveira
dc.contributor.authorLeal, Leonardo Martins
dc.contributor.authorOliveira, Fabricio Singaretti de [UNESP]
dc.contributor.authorFratini, Paula
dc.contributor.authorBerger, Trish
dc.contributor.authorFernandes Machado, Marcia Rita [UNESP]
dc.contributor.authorMiglino, Maria Angelica
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUninga Dept Med Vet
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniv Calif Davis
dc.date.accessioned2021-06-25T12:24:02Z
dc.date.available2021-06-25T12:24:02Z
dc.date.issued2020-12-01
dc.description.abstractThe study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spennatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.en
dc.description.affiliationUniv Sao Paulo FMVZ USP, Sch Vet Med & Anim Sci, Dept Surg, Av Prof Dr Orlando Marques de Paiva 87, BR-05508270 Sao Paulo, SP, Brazil
dc.description.affiliationUninga Dept Med Vet, Fac Ingn, Rod PR 317,6114 Parque Ind Duzentos, BR-87035510 Maringa, PR, Brazil
dc.description.affiliationUniv State Sao Paulo FCAV UNESP, Dept Anim Morphol & Physiol, Via Acesso Prof Paulo Donato Castellane S-N, BR-14884900 Jaboticabal, SP, Brazil
dc.description.affiliationUniv Calif Davis, Dept Anim Sci, 1 Shields Ave, Davis, CA 95616 USA
dc.description.affiliationUnespUniv State Sao Paulo FCAV UNESP, Dept Anim Morphol & Physiol, Via Acesso Prof Paulo Donato Castellane S-N, BR-14884900 Jaboticabal, SP, Brazil
dc.format.extent1525-1527
dc.identifier.citationInternational Journal Of Morphology. Temuco: Soc Chilena Anatomia, v. 38, n. 6, p. 1525-1527, 2020.
dc.identifier.issn0717-9502
dc.identifier.urihttp://hdl.handle.net/11449/209616
dc.identifier.wosWOS:000585776700001
dc.language.isoeng
dc.publisherSoc Chilena Anatomia
dc.relation.ispartofInternational Journal Of Morphology
dc.sourceWeb of Science
dc.subjectGonadal
dc.subjectToxic
dc.subjectSpermatogenesis
dc.titleThe Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitoren
dc.typeArtigo
dcterms.rightsHolderSoc Chilena Anatomia
dspace.entity.typePublication
unesp.departmentMorfologia e Fisiologia Animal - FCAVpt

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Jaboticabal - FCAV - Faculdade de Ciências Agrárias e Veterinárias