Publicação:
Focal invasiveness in complete histological analyses of a large acral lentiginous melanoma

dc.contributor.authorCaldeira Xavier-Júnior, Jose Candido [UNESP]
dc.contributor.authorMunhoz, Tania [UNESP]
dc.contributor.authorSouza, Vinicius [UNESP]
dc.contributor.authorPires de Campos, Eloisa Bueno [UNESP]
dc.contributor.authorStolf, Hamilton Ometto [UNESP]
dc.contributor.authorAlencar Marques, Mariangela Esther [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2015-10-21T13:08:58Z
dc.date.available2015-10-21T13:08:58Z
dc.date.issued2015-06-20
dc.description.abstractBackground: Acral lentiginous melanoma is a melanoma with poor prognosis which is frequently diagnosed at an advanced stage. Since the thickness of tumour is one of the main prognostic factors, this case can exemplify how important complete histological analyses looking for focal invasiveness can be.Case report: A 77 year-old woman with a black spot with slow progressive growth on the left plantar region. She sought medical attention due to the expansion onto the dorsal surface of toes. The lesion had irregular borders and had spread to half the plantar surface. Histopathology confirmed the clinical suspicion of acral lentiginous melanoma Clark level IV and 2.6 mm Breslow thickness. The surgical specimen was entirely processed for histological evaluation, requiring 53 slides. Tumor dermal invasion was detected in only three out of 53 glass slides as the invasiveness was not identified by clinical, dermatoscopy or macroscopy exams.Conclusion: Sectioning through the entire lesion is considered very important to determinate the appropriate stage of the disease and the correct treatment and patient follow-up.en
dc.description.affiliationUnespUNESP- Universidade Estadual Paulista Radiology and Dermatology Department, Botucatu, SP, Brazil
dc.description.affiliationUnespDepartment of Pathology, Botucatu Medical School, Paulista State University (UNESP), Rubião Júnior s/n 18618-970, Botucatu, SP, Brazil.
dc.format.extent1-4
dc.identifierhttp://www.diagnosticpathology.org/content/10/1/73
dc.identifier.citationDiagnostic Pathology. London: Biomed Central Ltd, v. 10, p. 1-4, 2015.
dc.identifier.doi10.1186/s13000-015-0307-z
dc.identifier.fileWOS000356654300001.pdf
dc.identifier.issn1746-1596
dc.identifier.lattes1885384405893048
dc.identifier.urihttp://hdl.handle.net/11449/128321
dc.identifier.wosWOS:000356654300001
dc.language.isoeng
dc.publisherBiomed Central Ltd
dc.relation.ispartofDiagnostic Pathology
dc.relation.ispartofjcr2.396
dc.relation.ispartofsjr0,818
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectMelanomaen
dc.subjectDermatopathologyen
dc.subjectCanceren
dc.subjectAcral Lentiginous Melanomaen
dc.titleFocal invasiveness in complete histological analyses of a large acral lentiginous melanomaen
dc.typeArtigo
dcterms.rightsHolderBiomed Central Ltd
dspace.entity.typePublication
unesp.author.lattes1885384405893048
unesp.author.orcid0000-0003-0503-419X[1]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.departmentDermatologia e Radioterapia - FMBpt
unesp.departmentPatologia - FMBpt

Arquivos

Pacote Original

Agora exibindo 1 - 1 de 1
Carregando...
Imagem de Miniatura
Nome:
WOS000356654300001.pdf
Tamanho:
2.27 MB
Formato:
Adobe Portable Document Format