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The role of SOX family in cancer stem cell maintenance: With a focus on SOX2

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dc.contributor.authorPouremamali, Farhad
dc.contributor.authorVahedian, Vahid [UNESP]
dc.contributor.authorHassani, Nasrin
dc.contributor.authorMirzaei, Sepideh
dc.contributor.authorPouremamali, Amir
dc.contributor.authorKazemzadeh, Hamid
dc.contributor.authorFaridvand, Yousef
dc.contributor.authorJafari-gharabaghlou, Davoud
dc.contributor.authorNouri, Mohammad
dc.contributor.authorMaroufi, Nazila Fathi
dc.contributor.institutionTabriz University of Medical Sciences
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionIslamic Azad University
dc.contributor.institutionScience and Research Branch
dc.contributor.institutionTarbiat Modares University
dc.date.accessioned2022-04-28T19:50:13Z
dc.date.available2022-04-28T19:50:13Z
dc.date.issued2022-03-01
dc.description.abstractThe role of cancer stem cells (CSCs) in cancer incidence, drug resistance, and relapse after chemotherapy has been discussed and it has been confirmed that CSCs are extremely important and so, are suitable for therapeutic targeting. Sox families play an important role in carcinogenesis and dis-regulation of SOXs molecules has been observed in different types of cancers. The members of this family have been shown to play an important role in the maintenance of CSCs. In this article, we have tried to evaluate the role of different family members in CSCs maintenance, review various studies in this field and provide a perspective view on this issue. Also, due to the important role and many studies in the field of SOX2 molecule in CSCs, we try to have more focus on this molecule and examine the potential of these molecules for therapeutic targeting.en
dc.description.affiliationDepartment of Medical Biotechnology Faculty of Advanced Medical Sciences Tabriz University of Medical Sciences
dc.description.affiliationCancer Biology Research Group Faculty of Medicine Institute of Biotechnology (FMB-IBTEC) Sao Paulo State University (UNESP)
dc.description.affiliationDepartment of Biology Islamic Azad University
dc.description.affiliationDepartment of Biology Faculty of Science Islamic Azad University Science and Research Branch
dc.description.affiliationDepartment of Virology Faculty of Medical Sciences Tarbiat Modares University
dc.description.affiliationDepartment of Biochemistry and Clinical Laboratories Faculty of Medicine Tabriz University of Medical Sciences
dc.description.affiliationUnespCancer Biology Research Group Faculty of Medicine Institute of Biotechnology (FMB-IBTEC) Sao Paulo State University (UNESP)
dc.identifierhttp://dx.doi.org/10.1016/j.prp.2022.153783
dc.identifier.citationPathology Research and Practice, v. 231.
dc.identifier.doi10.1016/j.prp.2022.153783
dc.identifier.issn1618-0631
dc.identifier.issn0344-0338
dc.identifier.scopus2-s2.0-85123773477
dc.identifier.urihttp://hdl.handle.net/11449/223368
dc.language.isoeng
dc.relation.ispartofPathology Research and Practice
dc.sourceScopus
dc.subjectCancer Stem Cells
dc.subjectDrug resistance
dc.subjectMaintenance
dc.subjectSOX family
dc.subjectSOX2
dc.titleThe role of SOX family in cancer stem cell maintenance: With a focus on SOX2en
dc.typeResenhapt
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biotecnologia, Botucatupt

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Botucatu - FMB - Faculdade de Medicina
Botucatu - IBTEC - Instituto de Biotecnologia