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Association between MUC1 gene polymorphism and expected progeny differences in Nelore cattle (Bos primigenius indicus)

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dc.contributor.authorSouza, Fabio Ricardo Pablos de
dc.contributor.authorVozzi, Pedro Alejandro
dc.contributor.authorVila, Reginaldo Aparecido
dc.contributor.authorBoligon, Arione Augusti [UNESP]
dc.contributor.authorGalerani, Marli Aparecida Vani
dc.contributor.authorLobo, Raysildo Barbosa
dc.contributor.authorMartelli, Lucia Regina
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:18:43Z
dc.date.available2014-05-20T13:18:43Z
dc.date.issued2010-01-01
dc.description.abstractMUC1 is a heavily glycosylated mammalian transmembrane protein expressed by mucosal secretory tissues for both protection against microbial infection and lubrication. An important characteristic of MUC1 is its variable number of tandem repeats (VNTR) containing several sites for O-glycosylation. VNTR length has been associated with many human diseases and with certain economically important traits in domestic ruminants. The aim of the present study was to correlate the length of MUC1 gene VNTR with expected progeny differences (EPDs) obtained for growth, fertility and carcass traits. Five alleles were identified, with alleles containing short VNTRs being more frequent than those with long, thereby demonstrating that Brazilian Nelore cattle are characterized by high frequencies in short MUC1 VNTRs. Statistical analyses revealed there to be no significant association between VNTR length and EPDs for weight at 120 days (W120), scrotal circumference at 365 (SC365) and 450 (SC450) days, age at first calving (AFC), and rib eye area (REA).en
dc.description.affiliationUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto Departamento de Genética
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho Faculdade de Ciências Agrárias e Veterinárias Departamento de Zootecnia
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho Faculdade de Ciências Agrárias e Veterinárias Departamento de Zootecnia
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent68-70
dc.identifierhttp://dx.doi.org/10.1590/S1415-47572009005000098
dc.identifier.citationGenetics and Molecular Biology. Sociedade Brasileira de Genética, v. 33, n. 1, p. 68-70, 2010.
dc.identifier.doi10.1590/S1415-47572009005000098
dc.identifier.fileS1415-47572010000100013.pdf
dc.identifier.issn1415-4757
dc.identifier.scieloS1415-47572010000100013
dc.identifier.urihttp://hdl.handle.net/11449/4700
dc.identifier.wosWOS:000275106000013
dc.language.isoeng
dc.publisherSociedade Brasileira de Genética
dc.relation.ispartofGenetics and Molecular Biology
dc.relation.ispartofjcr1.493
dc.relation.ispartofsjr0,638
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectBeef cattleen
dc.subjectMolecular markeren
dc.subjectProductive traitsen
dc.subjectquantitative trait locusen
dc.titleAssociation between MUC1 gene polymorphism and expected progeny differences in Nelore cattle (Bos primigenius indicus)en
dc.typeArtigo
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt
unesp.departmentZootecnia - FCAVpt

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Jaboticabal - FCAV - Faculdade de Ciências Agrárias e Veterinárias