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GENOTOXIC AND MUTAGENIC EFFECTS OF DIFLUBENZURON, AN INSECT GROWTH REGULATOR, ON MICE

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dc.contributor.authorBarros, Aline Lima de
dc.contributor.authorSouza, Vanessa Vilamaior de
dc.contributor.authorNavarro, Stephanie Dynczuki
dc.contributor.authorOesterreich, Silvia Aparecida
dc.contributor.authorOliveira, Rodrigo Juliano
dc.contributor.authorLeite Kassuya, Candida Aparecida
dc.contributor.authorArena, Arielle Cristina [UNESP]
dc.contributor.institutionUniversidade Federal da Grande Dourados (UFGD)
dc.contributor.institutionUniversidade Federal de Mato Grosso do Sul (UFMS)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-12-03T13:10:56Z
dc.date.available2014-12-03T13:10:56Z
dc.date.issued2013-09-02
dc.description.abstractThis study assessed the genotoxic and mutagenic potential of diflubenzuron (DFB) insecticide in mice. Mice were divided into five groups: group I: negative control; group II: positive control; group III: 0.3 mg/kg of DFB; group IV: 1 mg/kg of DFB; group V: 3 mg/kg DFB. Peripheral blood was collected for the comet assay and the micronucleus (MN) test. DFB increased incidence of comet formation at all doses tested. A rise in the frequency of MN in mouse peripheral blood was observed 24, 48, and 72 h postexposure at all doses tested. Data demonstrate that DFB exerts genotoxic and mutagenic effects in a dose-dependent manner.en
dc.description.affiliationUFGD, Sch Hlth Sci, Dourados, MS, Brazil
dc.description.affiliationFed Univ Mato Grosso do Sul UFMS Campo Grande, Campo Grande, MS, Brazil
dc.description.affiliationSao Paulo State Univ UNESP, Inst Biosci Botucatu, Dept Morphol, Botucatu, SP, Brazil
dc.description.affiliationUnespSao Paulo State Univ UNESP, Inst Biosci Botucatu, Dept Morphol, Botucatu, SP, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent1003-1006
dc.identifierhttp://dx.doi.org/10.1080/15287394.2013.830585
dc.identifier.citationJournal Of Toxicology And Environmental Health-part A-current Issues. Philadelphia: Taylor & Francis Inc, v. 76, n. 17, p. 1003-1006, 2013.
dc.identifier.doi10.1080/15287394.2013.830585
dc.identifier.issn1528-7394
dc.identifier.lattes0729220781785349
dc.identifier.urihttp://hdl.handle.net/11449/112663
dc.identifier.wosWOS:000326222200001
dc.language.isoeng
dc.publisherTaylor & Francis Inc
dc.relation.ispartofJournal of Toxicology and Environmental Health: Part A Current Issues
dc.relation.ispartofjcr2.706
dc.relation.ispartofsjr0,888
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleGENOTOXIC AND MUTAGENIC EFFECTS OF DIFLUBENZURON, AN INSECT GROWTH REGULATOR, ON MICEen
dc.typeArtigo
dcterms.licensehttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dcterms.rightsHolderTaylor & Francis Inc
dspace.entity.typePublication
unesp.author.lattes0729220781785349[7]
unesp.author.orcid0000-0002-8998-9219[6]
unesp.author.orcid0000-0002-2373-9399[7]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.departmentMorfologia - IBBpt

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Botucatu - IBB - Instituto de Biociências