Publicação:
Influence of Bioactive Glass and/or Acellular Dermal Matrix on Bone Healing of Surgically Created Defects in Rat Tibiae: A Histological and Histometric Study

dc.contributor.authorGasparini Ribeiro, Luciana Liarte [UNESP]
dc.contributor.authorBosco, Álvaro Francisco [UNESP]
dc.contributor.authorNagata, Maria José Hitomi [UNESP]
dc.contributor.authorNascimento de Melo, Luiz Gustavo [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2013-09-30T18:29:27Z
dc.date.accessioned2014-05-20T13:43:16Z
dc.date.available2013-09-30T18:29:27Z
dc.date.available2014-05-20T13:43:16Z
dc.date.issued2008-09-01
dc.description.abstractThe purpose of this study was to histologically analyze the influence of bioactive glass and/or acellular dermal matrix on bone healing in surgically created defects in the tibiae of 64 rats (Rattus norvegicus, albinus, Wistar). Materials and Methods: A 4-mm X 3-mm unicortical defect was created on the anterolateral surface of the tibia. Animals were divided into 4 groups: C, control; BG, the defect was filled with bioactive glass; ADM, the defect was covered with acellular dermal matrix; and BG/ADM, the defect was filled with bioactive glass and covered with acellular dermal matrix. Animals were sacrificed at 10 or 30 days postoperatively, and the specimens were removed for histologic processing. The formation of new bone in the cortical area of the defect was evaluated histomorphometrically. Results: At 10 and 30 days postoperatively, groups C (39.65% +/- 5.63% / 63.34% +/- 5.22%) and ADM (38.12% +/- 5.53 / 58.96% +/- 7.05%) presented a larger amount of bone formation compared to the other groups (P<.05). In the same periods, groups BG (13.10% +/- 6.29% / 29.5% +/- 5.56%) and BG/ADM (20.72% +/- 8.31% / 24.19% +/- 6.69%) exhibited statistically similar new bone formation. However, unlike the other groups, group BG/ADM did not present a significant increase in bone formation between the 2 time points. Conclusion: Based on these results, it can be concluded that all of the materials used in this study delayed bone healing in non-critical-size defects. INT J ORAL MAXILLOFAC IMPLANTS 2008;23:811-817en
dc.description.affiliationUniv State São Paulo Julio Mesquita Filho UNESP, Dent Sch Aracatuba, Dept Surg, Aracatuba, SP, Brazil
dc.description.affiliationUniv State São Paulo Julio Mesquita Filho UNESP, Dent Sch Aracatuba, Integrated Clin, Aracatuba, SP, Brazil
dc.description.affiliationUniv State São Paulo Julio Mesquita Filho UNESP, Dent Sch Aracatuba, Dept Surg, Div Periodont, Aracatuba, SP, Brazil
dc.description.affiliationUnespUniv State São Paulo Julio Mesquita Filho UNESP, Dent Sch Aracatuba, Dept Surg, Aracatuba, SP, Brazil
dc.description.affiliationUnespUniv State São Paulo Julio Mesquita Filho UNESP, Dent Sch Aracatuba, Integrated Clin, Aracatuba, SP, Brazil
dc.description.affiliationUnespUniv State São Paulo Julio Mesquita Filho UNESP, Dent Sch Aracatuba, Dept Surg, Div Periodont, Aracatuba, SP, Brazil
dc.format.extent811-817
dc.identifierhttp://www.quintpub.com/journals/omi/abstract.php?article_id=3580#.Ui9lDsbks_Y
dc.identifier.citationInternational Journal of Oral & Maxillofacial Implants. Hanover Park: Quintessence Publishing Co Inc, v. 23, n. 5, p. 811-817, 2008.
dc.identifier.issn0882-2786
dc.identifier.lattes9831236034935598
dc.identifier.lattes8399870097572073
dc.identifier.urihttp://hdl.handle.net/11449/15076
dc.identifier.wosWOS:000260332100002
dc.language.isoeng
dc.publisherQuintessence Publishing Co Inc
dc.relation.ispartofInternational Journal of Oral & Maxillofacial Implants
dc.relation.ispartofjcr1.699
dc.relation.ispartofsjr1,576
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.subjectacellular dermisen
dc.subjectbioactiveen
dc.subjectbioglassen
dc.subjectbone regenerationen
dc.subjectbone substitutesen
dc.titleInfluence of Bioactive Glass and/or Acellular Dermal Matrix on Bone Healing of Surgically Created Defects in Rat Tibiae: A Histological and Histometric Studyen
dc.typeArtigopt
dcterms.licensehttp://www.quintpub.com/journals/jop/orderreprints.php
dcterms.rightsHolderQuintessence Publishing Co Inc
dspace.entity.typePublication
relation.isOrgUnitOfPublication8b3335a4-1163-438a-a0e2-921a46e0380d
relation.isOrgUnitOfPublication.latestForDiscovery8b3335a4-1163-438a-a0e2-921a46e0380d
unesp.author.lattes9831236034935598
unesp.author.lattes8399870097572073
unesp.author.orcid0000-0001-5903-5652[3]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araçatubapt
unesp.departmentCirurgia e Clínica Integrada - FOApt

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