Publicação: Effect of age and sex on bone markers in Chlorocebus aethiops raised in captivity
Carregando...
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Wiley-Blackwell
Tipo
Artigo
Direito de acesso
Acesso restrito
Resumo
BackgroundThe objective was to evaluate the procollagen type I N-propeptide (PINP), osteocalcin (OC), -crosslaps (-CTX), and parathyroid hormone (PTH) in relation to age and sex of Chlorocebus aethiops in captivity. MethodsSeventy-three monkeys were divided into four age groups: AG1 (juvenile); AG2 (young adult); AG3 (adult); and AG4 (senile). An electrochemiluminescence immunoassay with an Elecsys 2010 analyzer was used to determine the serum markers of bone. Results and conclusionsSex did not influence the results of the markers. However, the variables PINP, OC, and -CTX were negatively correlated with age (r = -0.643; r = -0.711; r = -0.488; P < 0.001, respectively), and PTH was correlated positively with age (r = 0.418, P < 0.001). The data obtained can be used as biomarkers of bone metabolism reference intervals in healthy C. aethiops in captivity.
Descrição
Palavras-chave
bone formation markers of bone resorption markers, Cercopithecidae, primates
Idioma
Inglês
Como citar
Journal Of Medical Primatology. Hoboken: Wiley, v. 45, n. 1, p. 3-11, 2016.
