• Enhanced expression of NLRP3 inflammasome components by monocytes of patients with pulmonary paracoccidioidomycosis is associated with smoking and intracellular hypoxemia 

  Amorim, Barbara Casella ; Pereira-Latini, Ana Carla; Golim, Márjorie de Assis ; Ruiz Júnior, Raul Lopes ; Yoo, Hugo Hyung Bok ; Arruda, Maria Sueli Parreira de ; Tavares, Aldo Henrique; Cavalcante, Ricardo de Souza ; Mendes, Rinaldo Poncio ; Pontillo, Alessandra et al. (Microbes and Infection, 2020) [Artigo]

  Paracoccidioidomycosis (PCM) is a systemic mycosis caused by thermally dimorphic fungi of the genus Paracoccidioides that affects predominantly 30-60-year-old male rural workers. The main clinical forms of the disease are ...

• Proteomic analyses unraveling water stress response in two Eucalyptus species originating from contrasting environments for aridity 

  Martins, Rayana de Sá; Faria, José Marcio Rocha; Rossini, Bruno César ; Marino, Celso Luís ; dos Santos, Lucilene Delazari ; José, Anderson Cleiton (Molecular Biology Reports, 2020) [Artigo]

  Eucalyptus are widely cultivated in several regions of the world due to their adaptability to different climatic conditions and amenable to tree breeding programs. With changes in environmental conditions pointing to an ...

• Should we be concerned about COVID-19 with nonhuman primates? 

  Santos, Wesley José ; Guiraldi, Lívia Maísa ; Lucheis, Simone Baldini (American Journal of Primatology, 2020) [Nota]

  The coronavirus disease 2019 pandemic has radically changed the human activities worldwide. Although we are still learning about the disease, it is necessary that primatologists, veterinarians, and all that are living with ...

• Anthelmintic drugs for treating ascariasis 

  Conterno, Lucieni O; Turchi, Marilia D; Corrêa, Ione ; Monteiro de Barros Almeida, Ricardo Augusto (Cochrane Database of Systematic Reviews, 2020) [Resenha]

  Background: Ascaris lumbricoides is a common infection, and mainly affects children living in low-income areas. Water and sanitation improvement, health education, and drug treatment may help break the cycle of transmission, ...

• Predictors of relapse of visceral leishmaniasis in inner São Paulo State, Brazil 

  Simão, José Cláudio ; Victória, Cassiano ; Fortaleza, Carlos Magno Castelo Branco (International Journal of Infectious Diseases, 2020) [Artigo]

  Objectives: Visceral leishmaniasis (VL) is a public health threat for several tropical countries, including Brazil. Therapy failures and relapses aggravate VL morbidity and mortality. Our study aimed at identifying predictors ...

• Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation 

  de Oliveira, Larissa Ragozo Cardoso ; Mimura, Luiza Ayumi Nishiyama ; Fraga-Silva, Thais Fernanda de Campos ; Ishikawa, Larissa Lumi Watanabe ; Fernandes, Ana Angélica Henrique ; Zorzella-Pezavento, Sofia Fernanda Gonçalves ; Sartori, Alexandrina (Frontiers in Pharmacology, 2020) [Artigo]

  Multiple sclerosis (MS) is a progressive disease of the central nervous system (CNS) that involves damage to the myelin sheath surrounding axons. MS therapy is based on immunomodulatory drugs that reduce disease recurrence ...

• Accuracy of serological tests for diagnosis of chronic pulmonary aspergillosis: A systematic review and meta-analysis 

  Chaves, Cláudia Elizabeth Volpe; de Oliveira, Sandra Maria do Valle Leone; Venturini, James; Grande, Antonio Jose; Sylvestre, Tatiane Fernanda ; Mendes, Rinaldo Poncio ; Paniago, Anamaria Mello Miranda (PLoS ONE, 2020) [Artigo]

  Chronic pulmonary aspergillosis (CPA) is a slow and progressive disease that develops in preexisting lung cavities of patients with tuberculosis sequelae, and it is associated with a high mortality rate. Serological tests ...

• Frailty predicts surgical complications after kidney transplantation. A propensity score matched study 

  dos Santos Mantovani, Milena ; de Carvalho, Nyara Coelho ; Archangelo, Thomáz Eduardo ; de Andrade, Luis Gustavo Modelli ; Filho, Sebastião Pires Ferreira ; de Souza Cavalcante, Ricardo ; Kawano, Paulo Roberto ; Papini, Silvia Justina ; Costa, Nara Aline ; de Barros Almeida, Ricardo Augusto Monteiro (PLoS ONE, 2020) [Artigo]

  Background and objective Surgical complications after kidney transplantation can lead to catastrophic outcomes. Frailty has been associated with important kidney transplantation outcomes; however, there are no studies ...

• Relationship of spontaneous microembolic signals to risk stratification, recurrence, severity, and mortality of ischemic stroke: a prospective study 

  Bazan, Rodrigo ; Luvizutto, Gustavo José; Braga, Gabriel Pereira ; Bazan, Silméia Garcia Zanati ; Hueb, João Carlos ; de Freitas, Carlos Clayton Macedo ; Hamamoto Filho, Pedro Tadao ; Módolo, Gabriel Pinheiro ; Trindade, André Petean ; Sobreira, Marcone Lima et al. (Ultrasound Journal, 2020) [Artigo]

  Introduction: The presence of microembolic signals (MES) during the acute phase of stroke is poorly understood, and its role and clinical application in relation to risk stratification and prognosis in patients remain ...

• Epididymal protease inhibitor (EPPIN) is a protein hub for seminal vesicle-secreted protein SVS2 binding in mouse spermatozoa 

  Mariani, Noemia A.P. ; Camara, Aline C. ; Silva, Alan Andrew S. ; Raimundo, Tamiris R.F. ; Andrade, Juliana J. ; Andrade, Alexandre D. ; Rossini, Bruno C. ; Marino, Celso L. ; Kushima, Hélio ; Santos, Lucilene D. et al. (Molecular and Cellular Endocrinology, 2020) [Artigo]

  EPPIN is a sperm-surface drug target for male contraception. Here we investigated EPPIN-interacting proteins in mouse spermatozoa. We showed that EPPIN is an androgen-dependent gene, expressed in the testis and epididymis, ...

• Drivers of press media response to healthcare-associated infections caused by multidrug-resistant organisms: A report from Brazil 

  De Azevedo Carazatto, Priscila Zacarias ; Calil, Felipe Francischeti ; Fortaleza, Carlos Magno Castelo Branco (Infection Control and Hospital Epidemiology, 2020) [Carta]

• Transcriptional analysis of THP-1 cells infected with leishmania infantum indicates no activation of the inflammasome platform 

  Gatto, Mariana ; Borim, Patrícia Aparecida ; Wolf, Ivan Rodrigo ; da Cruz, Taís Fukuta ; Mota, Gustavo Augusto Ferreira ; Braz, Aline Márcia Marques ; Amorim, Bárbara Casella ; Valente, Guilherme Targino ; Golim, Marjorie de Assis ; Venturini, James et al. (PLoS Neglected Tropical Diseases, 2020) [Artigo]

  Leishmaniasis is caused by intracellular parasites transmitted to vertebrates by sandfly bites. Clinical manifestations include cutaneous, mucosal or visceral involvement depending upon the host immune response and the ...

• Proteomic analysis and antibacterial resistance mechanisms of Salmonella Enteritidis submitted to the inhibitory effect of Origanum vulgare essential oil, thymol and carvacrol 

  Barbosa, Lidiane Nunes ; Alves, Fernanda Cristina Bergamo ; Andrade, Bruna Fernanda Murbach Teles ; Albano, Mariana ; Rall, Vera Lucia Mores ; Fernandes, Ana Angélica Henrique ; Buzalaf, Marilia Afonso Rabelo; Leite, Aline de Lima; de Pontes, Leticia Gomes ; dos Santos, Lucilene Delazari et al. (Journal of Proteomics, 2020) [Artigo]

  Biological properties of natural products are an important research target and essential oils (EO) from aromatic plants with antimicrobial properties are well documented. However, their uses are limited, and the mechanisms ...

• Dynamics of plasma micronutrient concentrations and their correlation with serum proteins and thyroid hormones in patients with paracoccidioidomycosis 

  De Oliveira Custódio, Jeniffer Michelline; Enokida, Iasmim Mayumi; Gonçalves, Daniel Araujo; De Oliveira, Sandra Maria Do Valle Leone; Venturini, James; Carvalho, Lidia Raquel ; Mendes, Rinaldo Poncio ; Paniago, Anamaria Mello Miranda (PLoS ONE, 2019) [Artigo]

  Minerals, such as zinc, copper, and iron are reported to play roles in chronic infectious diseases; however, their role in paracoccidioidomycosis (PCM) remains unknown. This study aimed to examine the micronutrient dynamics ...

• Depression and coping are associated with failure of adherence to antiretroviral therapy among people living with HIV/aids 

  Camargo, Caio C. ; Cavassan, Nayara R. V. ; Tasca, Karen I. ; Meneguin, Silmara ; Miot, Hélio A. ; Souza, Lenice R. (AIDS Research and Human Retroviruses, 2019) [Artigo]

  Sustained adherence to antiretroviral therapy (ART) is critical in the prevention of drug resistance, disease progression, and death. We aimed to assess the level of ART adherence among 112 people living with HIV/AIDS ...

• Diversity of Blastocystis subtypes in wild mammals from a zoo and two conservation units in southeastern Brazil 

  Oliveira-Arbex, Ana Paula ; David, Érica Boarato ; Tenório, Michely da Silva ; Cicchi, Paulo José Pyles ; Patti, Mariella; Coradi, Silvana Torossian; Lucheis, Simone Baldini; Jim, Jorge ; Guimarães, Semíramis (Infection, Genetics and Evolution, 2020) [Artigo]

  The enteric protist Blastocystis is one of the most commonly parasite reported in humans and a variety of animal hosts worldwide. Regarding genetic diversity, at least 17 subtypes (STs) have been identified in mammals and ...

• Impact of laryngeal sequelae on voice-and swallowing-related outcomes in paracoccidioidomycosis 

  Carvalho Alves Pissurno, Neisa Santos; Esteves, Lucas da Motta; Benedito, Juliana Marques; Giglio, Vanessa Ponsano; Carvalho, Lidia Raquel de ; Mendes, Rinaldo Poncio ; Miranda Paniago, Anamaria Mello (Journal Of Venomous Animals And Toxins Including Tropical Diseases, 2020) [Artigo]

  Background: The present study was carried out aiming to evaluate the impact of laryngeal sequelae on the quality of life of treated paracoccidioidomycosis (PCM) patients. Methods: This cross-sectional study was conducted ...

• Domingos Alves Meira (star 1932 dagger 2012) Obituary 

  Machado, Jussara Marcondes (Revista Da Sociedade Brasileira De Medicina Tropical, 2012) [Biography]

• HUMAN BLOOD VENOM LEVELS AFTER AFRICANIZED HONEY BEE (APIS MELLIFERA) MASSIVE ATTACK AND ITS DEGRADOMIC ASPECTS 

  Tavares, Francilene Capel ; De Oliveira, Laudiceia Alves ; Barbosa, Alexandre Naime ; Mendes, Monica Bannwart ; Pimenta, Daniel Carvalho; Medolago, Natalia ; Oliveira, Ana Paula ; Carneiro, Marcia ; Ribeiro Da Cunha, Luis Eduardo; Carvalho, Edimilson R. M. et al. (Toxicon, 2019) [Resumo]

• Chronic venous ulcers: a review on treatment with fibrin sealant and prognostic advances using proteomic strategies 

  Fernandes Abbade, Luciana Patricia ; Ferreira, Rui Seabra ; Santos, Lucilene Delazari dos ; Barraviera, Benedito (Journal Of Venomous Animals And Toxins Including Tropical Diseases, 2020) [Resenha]

  Venous ulcers are the main causes of chronic lower-limb ulcers. The healing difficulties encourage the research and development of new products in order to achieve better therapeutic results. Fibrin sealant is one of these ...

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