Departamento de Doenças Tropicais e Diagnósticos por Imagem
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Translation, cultural adaptation and validation of the Somatic Symptom Scale-8 (SSS-8) for the Brazilian Portuguese language
(BMC Primary Care, 2022) [Artigo]Background: Assessment tools are commonly used in different fields of health to assist in the diagnosis, the evaluation of the response to treatment, the measurement of quality of life and the establishment of the prognosis. ... -
Transitions in frailty state 12 months after kidney transplantation: a prospective cohort study
(Journal of Nephrology, 2022) [Artigo]Background: Frailty is associated with several unfavorable outcomes after kidney transplantation (KTx). However, limited information is available regarding the transitions in frailty state and its components after KTx. ... -
Agreement between histopathological and intraoperative classifications for pediatric appendicitis and its relationship with the post-operative clinical outcome
(Frontiers in Pediatrics, 2022) [Artigo]Introduction: Some studies have shown poor agreement between intraoperative and histopathological classifications for appendicitis, despite their routine use in clinical practice. Objective: To investigate the agreement ... -
Frequency, spatial distribution, and genetic diversity of Blastocystis among referred individuals to a clinical laboratory: First report of subtype 9 in Brazil
(Acta Tropica, 2022) [Artigo]The enteric protist Blastocystis has a worldwide distribution, however its prevalence in the human population is still underestimated, especially in developing countries where proper diagnosis is not performed in the routine ... -
Cutaneous tuberculosis chancre: case description in a child
(Anais Brasileiros de Dermatologia, 2022) [Artigo] -
Launching a CDMO in Brazil aiming to develop biopharmaceuticals for clinical trials
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2022) [Artigo]The innovation timeline is expensive, risky, competitive, time-consuming, and laborintensive. In order to overcome such challenges and optimize financial resources, pharmaceutical companies nowadays hire contract development ... -
Tuberculosis
(Role of Oxidative Stress in Chronic Diseases, 2014) [Capítulo de livro]Tuberculosis (TB) has been present in man since pre-historic times. More than 100 yr after Robert Koch identified its causative agent in 1882, TB is still a chronic infection with one of the highest morbidity and mortality ... -
Using the internet to obtain dermatological information on patients from the public health network: a cross-sectional study
(Anais Brasileiros de Dermatologia, 2022) [Artigo] -
Association of CD209 (DC-SIGN) rs735240 SNV with paucibacillary leprosy in the Brazilian population and its functional effects
(Memorias do Instituto Oswaldo Cruz, 2022) [Artigo]BACKGROUND Leprosy, caused by Mycobacterium leprae, is a public health problem in Brazil that affects peripheral nerves, resulting in physical disabilities. During host-pathogen interactions, the immune response determines ... -
Effects of a Biocomplex Formed by Two Scaffold Biomaterials, Hydroxyapatite/Tricalcium Phosphate Ceramic and Fibrin Biopolymer, with Photobiomodulation, on Bone Repair
(Polymers, 2022) [Artigo]There are several treatment methods available for bone repair, although the effectiveness becomes limited in cases of large defects. The objective of this pre-clinical protocol was to evalu-ate the grafting of hydroxyapa ... -
Effect of Rapamycin on MOG-Reactive Immune Cells and Lipopolysaccharide-Activated Microglia: An in Vitro Approach for Screening New Therapies for Multiple Sclerosis
(Journal of Interferon and Cytokine Research, 2022) [Artigo]Rapamycin is an immunomodulatory drug that has been evaluated in preclinical and clinical trials as a disease-modifying therapy for multiple sclerosis (MS). In this study, we evaluated the in vitro effect of rapamycin on ... -
Bothrops leucurus snake venom protein profile, isolation and biological characterization of its major toxin PLA2s-like
(Toxicon, 2022) [Artigo]Bothrops leucurus is considered as a snake of medical interest in the State of Bahia, Brazil. However, so far, there are no studies that provide a refined mapping of the composition of this venom. The aim of this work was ... -
Factors associated with COVID-19 mortality in municipalities in the state of São Paulo (Brazil): an ecological study
(Revista da Sociedade Brasileira de Medicina Tropical, 2022) [Artigo]Background: The mortality rate of coronavirus disease (COVID-19) in the state of São Paulo is highly heterogeneous. This study investigated geographic, economic, social, and health-related factors associated with this ... -
SEQUENCE SLIDER: integration of structural and genetic data to characterize isoforms from natural sources
(Nucleic acids research, 2022) [Artigo]Proteins isolated from natural sources can be composed of a mixture of isoforms with similar physicochemical properties that coexist in the final steps of purification. Yet, even where unverified, the assumed sequence is ... -
Isolation, social stress, low socioeconomic status and its relationship to immune response in Covid-19 pandemic context
(Brain, Behavior, and Immunity - Health, 2020) [Resenha]The coronavirus disease 2019 (COVID-19) outbreak was first reported December 2019, in Wuhan, China, and has since spread worldwide. Social distancing or isolation measures were taken to mitigate the pandemic. Furthermore, ... -
Antifungal activity of liriodenine on clinical strains of Cryptococcus neoformans and Cryptococcus gattii species complexes
(Journal of Venomous Animals and Toxins including Tropical Diseases, 2022) [Artigo] -
Safety of the effective radiation dose received during stroke hospitalization
(Jornal Vascular Brasileiro, 2021) [Artigo]Background: Neuroimaging is widely used for diagnosis and treatment of stroke. However, little is known about whether the radiation doses received by patients comply with international safety guidelines. Objectives: The ... -
Proteomic analysis of serum samples of paracoccidioidomycosis patients with severe pulmonary sequel
(PLoS Neglected Tropical Diseases, 2021) [Artigo]Background Pulmonary sequelae (PS) in patients with chronic paracoccidioidomycosis (PCM) typically include pulmonary fibrosis and emphysema. Knowledge of the molecular pathways involved in PS of PCM is required for treatment ... -
Identification of Leishmania infantum and Leishmania braziliensis in captive primates from a zoo in Brazil
(American Journal of Primatology, 2022) [Artigo]Wild nonhuman primates (NHP) are considered natural hosts of a protozoan parasite from the genus Leishmania, the etiological agent of leishmaniasis. It is important to study the population of this infectious agent in zoo ... -
Quality and dose optimization in canine chest radiography using a digital radiography system
(Radiation Physics and Chemistry, 2022) [Artigo]Radiography is becoming increasingly popular as a diagnostic tool in veterinary radiology services. During radiological procedures, containment of the animal is often necessary to ensure a safe examination. This work aimed ...