• Outcomes in the management of high-risk gestational trophoblastic neoplasia in trophoblastic disease centers in South America 

  Maestá, Izildinha ; De Freitas Segalla Moreira, Marjory ; Rezende-Filho, Jorge; Bianconi, Maria Inés; Jankilevich, Gustavo; Otero, Silvina; Correa Ramirez, Luz Angela ; Sun, Sue Yazaki; Elias, Kevin; Horowitz, Neil et al. (International Journal of Gynecological Cancer, 2020) [Artigo]

  Background South America has a higher incidence of gestational trophoblastic disease than North America or Europe, but whether this impacts chemotherapy outcomes is unclear. The purpose of this study was to evaluate outcomes ...

• The involvement of annexin A1 in human placental response to maternal Zika virus infection 

  Molás, Rafaela Batista ; Ribeiro, Milene Rocha ; Ramalho dos Santos, Maria Juliana C; Borbely, Alexandre Urban; Oliani, Denise Vaz; Oliani, Antonio Hélio; Nadkarni, Suchita; Nogueira, Maurício Lacerda; Moreli, Jusciele Brogin; Oliani, Sonia Maria (Antiviral Research, 2020) [Artigo]

  The association of Zika virus infection (ZIKV) with congenital malformation and neurological sequelae brought a significant global concern. Recent studies have shown that maternal viral infection leads to inflammation in ...

• Prior exercise training and experimental myocardial infarction: A systematic review and meta-analysis 

  Veiga, Eduardo Carvalho de Arruda; de Melo, Brunno Lemes; Vieira, Stella de Souza; Simões, Ricardo S.; Valenti, Vitor E. ; Campos, Marcelo Ferraz; Do Vale, Joseane Elza Tonussi Mendez Rossetti; Rica, Roberta Lukesvicius; Soares-Júnior, José Maria; Baracat, Edmund Chada et al. (Clinics, 2020) [Resenha]

  Exercising prior to experimental infarction may have beneficial effects on the heart. The objective of this study was to analyze studies on animals that had exercised prior to myocardial infarction and to examine any ...

• Heart rate variability helps to distinguish the intensity of menopausal symptoms: A prospective, observational and transversal study 

  Martinelli, Patrícia Merly; Sorpreso, Isabel Cristina Esposito; Raimundo, Rodrigo Daminello; de Souza Leal, Osvaldo; Zangirolami-Raimundo, Juliana; de Lima, Marcos Venicius Malveira; Pérez-Riera, Andrés; Pereira, Valdelias Xavier; Elmusharaf, Khalifa; Valenti, Vitor E. et al. (PLoS ONE, 2020) [Artigo]

  Heart Rate Variability (HRV) represents cardiac autonomic behavior and have been related to menopausal symptoms, mainly vasomotor symptoms and their imbalance to cardiovascular risk. It is not clear in the literature which ...

• A Brazilian multicentre study evaluating pregnancies induced by cabergoline in patients harboring prolactinomas 

  Sant’ Anna, B. G.; Musolino, N. R.C.; Gadelha, M. R.; Marques, C.; Castro, M.; Elias, P. C.L.; Vilar, L.; Lyra, R.; Martins, M. R.A.; Quidute, A. R.P. et al. (Pituitary, 2020) [Artigo]

  Objective: To evaluate the maternal–fetal outcomes of CAB-induced pregnancies in patients with prolactinoma in a large cohort. Methods: The prevalence of tumor growth, miscarriage, preterm, low birth weight, congenital ...

• NAMPT levels are inversely related to nitric oxide formation and positively related to soluble fms-like tyrosine kinase-1 levels in preeclampsia 

  Pereira, Daniela A.; Sandrim, Valéria C. ; Palei, Ana C.T.; Tanus-Santos, Jose E.; Belo, Vanessa A.; Cavalli, Ricardo C.; Luizon, Marcelo R. (Pregnancy Hypertension, 2019) [Artigo]

  NAMPT is a biomarker for endothelial dysfunction, but its relationship with nitrite (marker of NO formation) and soluble fms-like tyrosine kinase-1 (sFLT-1) has not been previously evaluated in preeclampsia. Therefore, we ...

• Clinical characteristics and risk factors for mortality in obstetric patients with severe COVID-19 in Brazil: a surveillance database analysis 

  Takemoto, M. L.S. ; Menezes, M. O. ; Andreucci, C. B.; Knobel, R.; Sousa, L.; Katz, L.; Fonseca, E. B.; Nakamura-Pereira, M.; Magalhães, C. G. ; Diniz, C. S.G. et al. (BJOG: An International Journal of Obstetrics and Gynaecology, 2020) [Artigo]

  Objective: To describe clinical characteristics of pregnant and postpartum women with severe COVID-19 in Brazil and to examine risk factors for mortality. Design: Cross-sectional study based on secondary surveillance ...

• Infraphysiological 17β-estradiol (E2) concentration compromises osteoblast differentiation through Src stimulation of cell proliferation and ECM remodeling stimulus 

  Barneze Costa, Sarah Maria ; da Silva Feltran, Georgia ; Namba, Vickeline ; Silva, Tabata Marilda ; Shetty Hallur, Raghavendra Lakshmana ; Saraiva, Patrícia Pinto ; Zambuzzi, Willian Fernando ; Nogueira, Celia Regina (Molecular and Cellular Endocrinology, 2020) [Artigo]

  It has been shown that 17β-estradiol (E2) helps to prevent bone loss. This study was undertaken to verify whether E2 action in human osteoblasts involves changes in the transcriptional profile of the TNF-α, IFN-γ, NF-κB, ...

• Mitochondrial dysfunction in the fetoplacental unit in gestational diabetes mellitus 

  Sobrevia, Luis; Valero, Paola; Grismaldo, Adriana; Villalobos-Labra, Roberto; Pardo, Fabián; Subiabre, Mario; Armstrong, Gael; Toledo, Fernando; Vega, Sofía ; Cornejo, Marcelo et al. (Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020) [Resenha]

  Gestational diabetes mellitus (GDM) is a disease of pregnancy that is associated with D-glucose intolerance and foeto-placental vascular dysfunction. GMD causes mitochondrial dysfunction in the placental endothelium and ...

• Pelvic floor muscle training for women with lumbopelvic pain: A systematic review and meta-analysis 

  Vesentini, Giovana ; Prior, Joanna; Ferreira, Paulo H.; Hodges, Paul W.; Rudge, Marilza ; Ferreira, Manuela L. (European Journal of Pain (United Kingdom), 2020) [Resenha]

  Background and Objective: It has been suggested that pelvic floor dysfunction may contribute to the development of lumbopelvic pain as a result of changes in trunk muscle control. However, there is limited evidence that ...

• Impact of Gestational Diabetes Mellitus on Sexual Function: A Case-Control Study 

  Nunes, Sthefanie K. ; Rudge, Cibele V C ; Quiroz, Sofia C B V ; Hallur, Raghavendra L. ; Prudencio, Caroline B. ; Pinheiro, Fabiane A. ; Filho, Carlos I Sartorão ; Odland, Jon; Calderon, Iracema M P ; Barbosa, Angélica M P et al. (Journal of women's health (2002), 2020) [Artigo]

  Background: The prevalence of gestational diabetes mellitus (GDM) is increasing worldwide, and this condition may be compromising female sexual function. However, there are controversial findings regarding the impact of ...

• Impact of gestational diabetes on pelvic floor: A prospective cohort study with three-dimensional ultrasound during two-time points in pregnancy 

  Sartorão Filho, Carlos I. ; Pinheiro, Fabiane A. ; Prudencio, Caroline B. ; Nunes, Sthefanie K. ; Takano, Luiz ; Enriquez, Eusebio M. A. ; Orlandi, Maiara I. G. ; Junginger, Baerbel; Hallur, Raghavendra L. S. ; Rudge, Marilza V. C. et al. (Neurourology and Urodynamics, 2020) [Artigo]

  Aim: To evaluate the pelvic floor (PF) biometry using three-dimensional ultrasound (US) at two-time points of gestational in pregnant women with gestational diabetes mellitus (GDM). Methods: A prospective cohort study ...

• Worldwide maternal deaths due to COVID-19: A brief review 

  Nakamura-Pereira, Marcos; Betina Andreucci, Carla; de Oliveira Menezes, Mariane ; Knobel, Roxana; Takemoto, Maíra Libertad Soligo (International Journal of Gynecology and Obstetrics, 2020) [Artigo]

• Deleterious effects of gestational diabetes mellitus on the characteristics of the rectus abdominis muscle associated with pregnancy-specific urinary incontinence 

  Vesentini, Giovana ; Barbosa, Angélica M.P. ; Floriano, Juliana F. ; Felisbino, Sérgio L. ; Costa, Sarah M.B. ; Piculo, Fernanda ; Marini, Gabriela ; Nunes, Sthefanie K. ; Reyes, David R.A. ; Marcondes, João P.C. et al. (Diabetes Research and Clinical Practice, 2020) [Artigo]

  Aims: To evaluate the effects of gestational diabetes mellitus (GDM) on the structural characteristics of the rectus abdominis muscle (RAM) and its indirect effects on pregnancy-specific urinary incontinence (PSUI). Methods: ...

• Pregnancy-specific urinary incontinence in women with gestational hyperglycaemia worsens the occurrence and severity of urinary incontinence and quality of life over the first year post partum 

  Piculo, Fernanda ; Marini, Gabriela ; Vesentini, Giovana ; Morceli, Glilciane ; Damasceno, Débora C. ; Sobrevia, Luis; Barbosa, Angélica M.P. ; Rudge, Marilza V.C. (European Journal of Obstetrics and Gynecology and Reproductive Biology, 2020) [Artigo]

  Objective: To determine the occurrence and severity of pregnancy-specific urinary incontinence (PSUI) in women with gestational hyperglycaemia, and its impact on quality of life (QoL) over the first year post partum. Study ...

• Evaluation of Maternal Reproductive Outcomes and Biochemical Analysis from Wistar Audiogenic Rats (WAR) and Repercussions in Their Offspring 

  Moraes-Souza, Rafaianne Q. ; Sinzato, Yuri K. ; Antunes, Beatriz T. ; Umeoka, Eduardo H. L.; Oliveira, José Antônio C.; Garcia-Cairasco, Norberto; Karki, Barshana; Volpato, Gustavo T.; Damasceno, Débora Cristina (Reproductive Sciences, 2020) [Artigo]

  The objective of the present study was to evaluate maternal reproductive performance, body weight, and frequency of external and internal anomalies of newborns of Wistar Audiogenic Rat (WAR) females as compared with Wistar ...

• Oxidative stress biomarkers in newborn calves: Comparison among artificial insemination, in vitro fertilization and cloning 

  Dantas, Gabriela N. ; Santarosa, Bianca P. ; Santos, Vitor H.; Hooper, Henrique B.; Micai, Ricardo A.; Sinzato, Yuri K. ; Damasceno, Débora C. ; da Silva, Andreza A.; Benesi, Fernando J.; Gonçalves, Roberto C. (Animal Reproduction Science, 2020) [Artigo]

  Oxidative stress occurs when there is greater than optimal production of reactive oxygen species (ROS) or an antioxidant system failure. Calves produced using in vitro fertilization (IVF) or cloning (CA) have greater ...

• The impact of letrozole administration on oocyte morphology in breast cancer patients undergoing fertility preservation 

  Bercaire, Ludmila M.N. ; Cavagna, Mario; Donadio, Nilka F.; Rocha, Andressa R.; Portela, Rafael; Alves, Vanessa R.; Santos, Thamara B.B.; Cavagna, Felipe; Dzik, Artur; Gebrim, Luiz H. et al. (Jornal Brasileiro de Reproducao Assistida, 2020) [Artigo]

  Objective: Patients submitted to oncological fertility preservation with letrozole and gonadotropins seem to present a higher rate of immature oocytes and lower fertilization rates in comparison to infertile patients ...

• Heat Shock Protein 60 Antibodies Are Associated With a Risk Factor for Cardiovascular Disease in Bedridden Elderly Patients 

  de Lima Filho, Jonas Bernardes; Freire, Letícia; Nahas, Eliana Aguiar Petri ; Orsatti, Fábio Lera; Orsatti, Claudio Lera (Frontiers in Molecular Biosciences, 2020) [Artigo]

  Frailty, in elderly people, represents multiple deficiencies in different organs and is characterized by decreased physiological reserves and greater vulnerability to stressors. Bedridden elderly, with cardiovascular disease ...

• Maternal factors associated with hyperglycemia in pregnancy and perinatal outcomes: A Brazilian reference center cohort study 

  Nicolosi, Bianca F. ; Vernini, Joice M. ; Costa, Roberto A. ; Magalhães, Claudia G. ; Rudge, Marilza V. C. ; Corrente, José E. ; Cecatti, Jose G.; Calderon, Iracema M. P. (Diabetology and Metabolic Syndrome, 2020) [Artigo]

  Background: While sufficient evidence supporting universal screening is not available, it is justifiable to look for specific risk factors for gestational diabetes mellitus (GDM) or hyperglycemia in pregnancy (HIP). The ...

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