RSS 1.0Artigos - Ginecologia e Obstetrícia - FMB
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Silibinin downregulates the NF-κB pathway and NLRP1/NLRP3 inflammasomes in monocytes from pregnant women with preeclampsia
Matias, Mariana Leticia
; Gomes, Virginia Juliani ; Romao-Veiga, Mariana ; Ribeiro, Vanessa Rocha ; Nunes, Priscila Rezeck ; Romagnoli, Graziela Gorete ; Peracoli, Jose Carlos ; Peracoli, Maria Terezinha Serrao (Molecules, 2019) [Artigo]
Preeclampsia (PE) is a human pregnancy-specific syndrome with abnormal activation of cells from the innate immune system. The present study evaluated whether silibinin (SB) treatment of monocytes from preeclamptic women ... -
Role of plasma PlGF, PDGF-AA, ANG-1, ANG-2, and the ANG-1/ANG-2 ratio as predictors of preeclampsia in a cohort of pregnant women
; ; ; ; ; ; Sandrim, V. C.; ; ; et al. (Pregnancy Hypertension, 2019) [Artigo]
Introduction: Preeclampsia affects 3–5% of pregnancies worldwide and is the primary cause of maternal-fetal and neonatal mortality. Previous studies show that alterations in maternal concentrations of angiogenic factors, ... -
Metabolomics for predicting hyperglycemia in pregnancy: A protocol for a systematic review and potential meta-analysis
Nicolosi, Bianca Fioravanti; ; ; ; ; Calderon, Iracema De Mattos Paranhos (Systematic Reviews, 2019) [Resenha]
Background: Hyperglycemia in pregnancy (HIP) has been recently differentiated between diabetes in pregnancy (DIP) and gestational diabetes mellitus (GDM). The proposed protocol is relevant, and clinical concern is due to ... -
High risk for cardiovascular disease in postmenopausal breast cancer survivors
Buttros, Daniel De Araujo Brito; Branco, Mauro Terra ; Orsatti, Claudio Lera ; Almeida-Filho, Benedito De Sousa ; Nahas-Neto, Jorge ; Nahas, Eliana A.P. (Menopause, 2019) [Artigo]
Objective:Breast cancer patients have a higher mortality risk of cardiovascular disease (CVD) than women from the general population. CVD risk may increase significantly in postmenopausal women with early-stage breast ... -
Incidence and risk factors for Preeclampsia in a cohort of healthy nulliparous pregnant women: a nested case-control study
; ; ; ; ; ; Calderon, Iracema M.; ; ; et al. (Scientific reports, 2019) [Artigo]
The objective of this study is to determine the incidence, socio-demographic and clinical risk factors for preeclampsia and associated maternal and perinatal adverse outcomes. This is a nested case-control derived from the ... -
Carpal tunnel syndrome during the third trimester of pregnancy: prevalence and risk factors
Oliveira, Gladys Alexandra Dias de; Bernardes, João Marcos ; Santos, Elisiane de Souza ; Dias, Adriano (Archives of Gynecology and Obstetrics, 2019) [Artigo]
Purpose: To estimate the prevalence of indicative signs and symptoms of carpal tunnel syndrome (CTS) during the third trimester of pregnancy; assess the severity of symptoms and functional impairment; evaluate associated ... -
Downregulation of CD163 in monocytes and its soluble form in the plasma is associated with a pro-inflammatory profile in pregnant women with preeclampsia
Nunes, Priscila R.; Romão-Veiga, Mariana ; Peraçoli, José C. ; Araujo Costa, Roberto A. ; de Oliveira, Leandro G. ; Borges, Vera Therezinha M. ; Peraçoli, Maria Terezinha (Immunologic Research, 2019) [Artigo]
Preeclampsia (PE) is a pregnancy-specific syndrome characterized by a systemic inflammatory response that polarizes peripheral blood monocytes to the M1 phenotype. The classically activated M1 monocytes comprise immune ... -
Quality of life in patients who undergo conventional or robotic-assisted total laparoscopic hysterectomy: Protocol for a systematic review of randomized controlled trials
; Rodrigues, Meline Rossetto Kron; ; Rudge, Marilza Vieira Cunha ; Lima, Silvana Andréa Molina (Medicine (United States), 2019) [Resenha]
Background:Hysterectomy for benign gynecologic diseases, especially dysfunctional uterine bleeding, is one of the most common gynecologic interventions. The uterus can be removed using abdominal, vaginal, laparoscopic, or ... -
Altered maternal metabolism during mild gestational hyperglycemia as a predictor of adverse perinatal outcomes: A comprehensive analysis
Rudge, Marilza Vieira Cunha; Barbosa, Angélica Mercia Pascon ; Sobrevia, Luis ; Gelaleti, Rafael Bottaro ; Hallur, Raghavendra Lakshmana Shetty ; Marcondes, João Paulo Castro ; Salvadori, Daisy Maria Fávero ; Prudêncio, Caroline Baldini ; Magalhães, Claudia Garcia ; Costa, Roberto et al. (Biochimica et Biophysica Acta - Molecular Basis of Disease, 2019) [Resenha]
Mild gestational hyperglycemia (MGH), as assessed using the normal oral glucose tolerance test (OGTT) and detection of an altered glycemic profile, is associated with adverse perinatal outcome. This study described the ... -
Reply: ITADE flap after mastectomy for locally advanced breast cancer: A good choice for mid-sized defects of the chest wall based on a systematic review of thoracoabdominal flaps
Vieira, R. A.C.; ; (Journal of Surgical Oncology, 2019) [Carta]
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Temporal analysis of distribution pattern of islet cells and antioxidant enzymes for diabetes onset in postnatal critical development window in rats
Gallego, Franciane Quintanilha; Miranda, Carolina Abreu ; Sinzato, Yuri Karen ; Iessi, Isabela Lovizutto ; ; ; Rocha, Noeme Sousa ; ; Damasceno, Débora Cristina (Life Sciences, 2019) [Artigo]
Aim: At performing a temporal analysis of the distribution pattern of islet endocrine cells and antioxidant enzymes in diabetic rats during the post-natal critical development window. Main methods: The newborns received ... -
Metabolomics applied to maternal and perinatal health: A review of new frontiers with a translation potential
; ; ; ; Calderon, Iracema Mattos; ; ; ; ; et al. (Clinics, 2019) [Artigo]
The prediction or early diagnosis of maternal complications is challenging mostly because the main conditions, such as preeclampsia, preterm birth, fetal growth restriction, and gestational diabetes mellitus, are complex ... -
Efficacy of Vitamin D supplementation in gestational diabetes mellitus: Systematic review and meta-analysis of randomized trials
Rodrigues, Meline Rossetto Kron; Lima, Silvana Andréa Molina ; da Silvia Mazeto, Glaucia Maria Ferreira ; Calderon, Iracema Mattos Paranhos ; Magalhães, Claudia Garcia ; Ferraz, Guilherme Augusto Rago ; ; de Araújo Costa, Roberto Antônio ; Nogueira, Vania dos Santos Nunes ; Rudge, Marilza Vieira Cunha (PLoS ONE, 2019) [Resenha]
Background Trials have examined on the benefits of vitamin D supplementation in pregnant women. Objective This review aimed to evaluate whether oral vitamin D supplements, when given to pregnant women with gestational ... -
Prenatal exposure to gestational diabetes mellitus increases developmental defects in the enamel of offspring
Pascon, Tawana; Barbosa, Angélica M.P. ; Cordeiro, Rita C.L. ; Bussaneli, Diego G. ; Prudencio, Caroline B. ; Nunes, Sthefanie K. ; Pinheiro, Fabiane A. ; Bossolan, Grasiela ; Oliveira, Leandro G. ; Calderon, Iracema M.P. et al. (PLoS ONE, 2019) [Artigo]
Background and objective Gestational diabetes mellitus (GDM) is associated with short- and long-term maternal and perinatal repercussions. Our objective was to evaluate the long-term consequences of intrauterine exposure ... -
Low pretreatment serum concentration of vitamin D at breast cancer diagnosis in postmenopausal women
Machado, Murilo Renato Matos; ; ; ; ; (Menopause (New York, N.Y.), 2019) [Artigo]
OBJECTIVE: The aim of the study was to evaluate the rate of and risk factors for low pretreatment vitamin D (VitD) levels in postmenopausal breast cancer (BC) women, compared with postmenopausal women without BC. METHODS: ... -
Mitochondrial-related gene associated to obesity can be modulated by in utero hyperglycemic environment
Silveira, Maruhen A.D.; Marcondes, João Paulo C. ; Lara, Juliana R. ; Scarano, Wellerson R. ; Calderón, Iracema M.P. ; Rudge, Marilza V.C. ; Salvadori, Daisy M.F. (Reproductive Toxicology, 2019) [Artigo]
We investigated whether mitochondrial-related genes and proteins are modulated by hyperglycemia promoted by gestational diabetes (GDM), thereby increasing neonate obesity predisposition. 19 healthy pregnant women, 16 ... -
Is there an association between diabetes and neck and back pain? A systematic review with meta-analyses
; ; ; ; Vesentini, Giovana; ; (PLoS ONE, 2019) [Artigo]
Background and objective Approximately half of the population will experience either low back pain or neck pain, at some point in their lives. Previous studies suggest that people with diabetes are more likely to present ... -
Repercussions of low fructose-drinking water in male rats
; ; ; Sinzato, Yuri K.; Volpato, Gustavo T. ; Damasceno, Débora C. ; (Anais da Academia Brasileira de Ciencias, 2019) [Artigo]
Fructose consumption has increased worldwide, and it has been associated with the development of metabolic diseases such as insulin resistance (IR) and steatosis. The aim was to evaluate if lower fructose concentrations ... -
The role of laparoscopy in the propaedeutics of gynecological diagnosis
Argentino, Gislaine Laperuta Serafim; Bueloni-Dias, Flávia Neves ; Leite, Nilton José ; Peres, Gustavo Filipov ; Elias, Leonardo Vieira ; Bortolani, Vitória Cristina ; Padovani, Carlos Roberto ; Spadoto-Dias, Daniel ; Dias, Rogério (Acta Cirurgica Brasileira, 2019) [Artigo]
Purpose: To evaluate agreement between pre-and post-laparoscopy gynecological diagnosis in order to demonstrate the rationality of this minimally invasive technique use in gynecological propaedeutics. Methods: Retrospective ... -
Adolescent use of combined hormonal contraception and peak bone mineral density accrual: A meta-analysis of international prospective controlled studies
; ; ; Beres Lederer Goldberg, Tamara; ; (Clinical Endocrinology, 2019) [Resenha]
Objective: Many women use combined hormonal contraceptives (CHC) during adolescence during which they are accruing peak areal bone mineral density (BMD) that relates to lifetime fracture risk. To build BMD requires formation ...