• BCL2 and miR-181a transcriptional alterations in umbilical-cord blood cells can be putative biomarkers for obesity 

  Marcondes, João Paulo de Castro ; Andrade, Pablo Felipe Bertolini ; Sávio, André Luiz Ventura ; Silveira, Maruhen Amir Datsch ; Rudge, Marilza Vieira Cunha ; Salvadori, Daisy Maria Fávero (Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2018) [Artigo]

  Several findings suggest that in utero stressor stimuli can alter fetal development by promoting transcriptional changes, and predisposing the neonate to diseases later in life. This study aimed to investigate whether a ...

• Ficha de avaliação - Novas ações de aperfeiçoamento: Áreas de concentração e linhas de pesquisa/estrutura curricular/captação de recursos 

  Calderon, Iracema M. P. (Revista do Colegio Brasileiro de Cirurgioes, 2015) [Artigo]

  Objective: This review aims to develop a critical and current analysis of the basic structure of a Postgraduate program for proposing improvement actions and new evaluation criteria. Method: To examine the items that are ...

• Avaliação do qualis-periódicos da medicina III: Análise dos periódicos de anestesiologia e Ginecologia e obstetrícia 

  Calderon, Iracema de Mattos Paranhos (Revista do Colegio Brasileiro de Cirurgioes, 2015) [Artigo]

  Objective: To know the current publication of Anesthesiology and Obstetrics and Gynecology subareas, to support the updating of Qualis Journals criteria in these specific subareas. Method: Cross-sectional, descriptive study ...

• Novos rumos da pós-graduação estrito senso na área da cirurgia: Visão global e perspectivas de implementação na Medicina III/Capes 

  Lima, Wilma Terezinha Anselmo; Matias, Jorge Eduardo Fouto; Calderon, Iracema M.P. ; Malafaia, Osvaldo; Ribas-Filho, Jurandir Marcondes; Czeczko, Nicolau Gregori (Revista do Colegio Brasileiro de Cirurgioes, 2015) [Editorial]

• Use of metabolomics for the identification and validation of clinical biomarkers for preterm birth: Preterm SAMBA 

  Cecatti, Jose G.; Souza, Renato T.; Sulek, Karolina; Costa, Maria L.; Kenny, Louise C.; McCowan, Lesley M.; Pacagnella, Rodolfo C.; Villas-Boas, Silas G.; Mayrink, Jussara; Passini, Renato et al. (BMC Pregnancy and Childbirth, 2016) [Artigo]

  Background: Spontaneous preterm birth is a complex syndrome with multiple pathways interactions determining its occurrence, including genetic, immunological, physiologic, biochemical and environmental factors. Despite great ...

• Hyperglycemia differentially affects maternal and fetal DNA integrity and DNA damage response 

  Moreli, Jusciele B. ; Santos, Janine H.; Lorenzon-Ojea, Aline Rodrigues; Corrêa-Silva, Simone ; Fortunato, Rodrigo S.; Rocha, Clarissa Ribeiro; Rudge, Marilza V. ; Damasceno, Débora C. ; Bevilacqua, Estela; Calderon, Iracema M. (International Journal of Biological Sciences, 2016) [Artigo]

  Objective: Investigate the DNA damage and its cellular response in blood samples from both mother and the umbilical cord of pregnancies complicated by hyperglycemia. Methods: A total of 144 subjects were divided into 4 ...

• Maternal reproductive performance and fetal development of the Wistar Audiogenic Rat (WAR) strain 

  Umeoka, Eduardo H.; Eiras, Matheus C.; Viana, Iara G.; Giorgi, Vanessa S.; Bueno, Aline; Damasceno, Débora C.; Garcia-Cairasco, Norberto; Navarro, Paula A. (Systems Biology in Reproductive Medicine, 2018) [Artigo]

  Wistar Audiogenic Rat (WAR) strain is an animal model for epilepsy studies, the chronic multifactorial disease that affects millions of people worldwide. The animals of this strain are genetically predisposed to sound-induced ...

• C>T (rs17035945) polymorphism of TIMP-4 protects against preeclampsia 

  Sandrim, Valéria C.; Luizon, Marcelo R.; Machado, Jackeline S. R.; Cavalli, Ricardo C. (Journal of Obstetrics and Gynaecology, 2018) [Artigo]

• Detection and genotyping of human papillomavirus (HPV) in HIV-infected women and its relationship with HPV/HIV co-infection 

  Badial, Rodolfo Miglioli ; DIas, Marina Carrara ; Stuqui, Bruna ; Melli, Patrícia Pereira Dos Santos; Quintana, Silvana Maria; Bonfim, Caroline Measso Do ; Cordeiro, José Antônio; Rabachini, Tatiana; Calmon, Marilia De Freitas ; Provazzi, Paola Jocelan Scarin et al. (Medicine (United States), 2018) [Artigo]

  HPV have been identified as high-risk and low-risk, depending on their association with the development of cancer. HPV infections can be facilitated by co-infection with HIV. Here, we investigated HPV prevalence and genotypes ...

• Phenotypic characterization of regulatory T cells populations in maternal blood, cord blood and placenta from diabetic mothers 

  Queiroz, Adriele A.; França, Eduardo L.; Hara, Cristiane C. P.; Honorio, Mariana S.; Fagundes, Danny L. G.; Calderon, Iracema M. P.; Honorio-França, Adenilda C. (Journal of Maternal-Fetal and Neonatal Medicine, 2017) [Artigo]

  Purpose: Changes in regulatory T cells (Treg) in peripheral blood are associated with a number of pathologies, including diabetes. However, the immunological responses of pregnant diabetic women remain scarcely known, and ...

• Effects of estrogen status in osteocyte autophagy and its relation to osteocyte viability in alveolar process of ovariectomized rats 

  Florencio-Silva, Rinaldo; Sasso, Gisela R.S.; Sasso-Cerri, Estela ; Simões, Manuel J.; Cerri, Paulo S. (Biomedicine and Pharmacotherapy, 2018) [Artigo]

  Estrogen maintains osteocyte viability, whereas its deficiency induces osteocyte apoptosis. As autophagy is important for osteocyte viability, we hypothesized whether the anti-apoptotic effect of estrogen is related to ...

• Circulating microRNA expression profiles in pre-eclampsia: evidence of increased miR-885-5p levels 

  Sandrim, V. C.; Luizon, M. R.; Palei, A. C.; Tanus-Santos, J. E.; Cavalli, R. C. (BJOG : an international journal of obstetrics and gynaecology, 2016) [Artigo]

  OBJECTIVE: To validate and to compare the circulating microRNA (miR) expression profiles between pre-eclampsia and healthy pregnant women, to perform correlation analysis of the differently expressed miRs with clinical and ...

• Dataset on lipid profile of bovine oocytes exposed to Lα-phosphatidylcholine during in vitro maturation investigated by MALDI mass spectrometry and gas chromatography-flame ionization detection 

  Vireque, Alessandra A.; Ferreira, Christina R.; Hatanaka, Rafael R. ; Tata, Alessandra; Belaz, Katia Roberta A.; Santos, Vanessa G.; Eberlin, Marcos N.; Silva de Sá, Marcos Felipe; Ferriani, Rui A.; Rosa e Silva, Ana Carolina J.S. (Data in Brief, 2017) [Artigo]

  Data presented in this article are related with the research article entitled “Effect of soybean phosphatidylcholine on lipid profile of bovine oocytes matured in vitro” [1]. This article describes the differences in the ...

• Breast cancer screening in developing countries 

  da Costa Vieira, René Aloísio ; Biller, Gabriele; Uemura, Gilberto ; Ruiz, Carlos Alberto; Curado, Maria Paula (Clinics, 2017) [Resenha]

  Developing countries have limited healthcare resources and use different strategies to diagnose breast cancer. Most of the population depends on the public healthcare system, which affects the diagnosis of the tumor. Thus, ...

• Osteoporosis and autophagy: What is the relationship? 

  Florencio-Silva, Rinaldo; Da Silva Sasso, Gisela Rodrigues; De Jesus Simões, Manuel; Simões, Ricardo Santos; Baracat, Maria Cândida Pinheiro; Sasso-Cerri, Estela ; Sérgio Cerri, Paulo (Revista da Associacao Medica Brasileira, 2017) [Resenha]

  Autophagy is a survival pathway wherein non-functional proteins and organelles are degraded in lysosomes for recycling and energy production. Therefore, autophagy is fundamental for the maintenance of cell viability, acting ...

• Sperm morphometry and chromatin condensation in Nelore bulls of different ages and their effects on IVF 

  Kipper, B. H. ; Trevizan, J. T. ; Carreira, J. T.; Carvalho, I. R. ; Mingoti, G. Z. ; Beletti, M. E.; Perri, S. H.V. ; Franciscato, D. A. ; Pierucci, J. C. ; Koivisto, M. B. (Theriogenology, 2017) [Artigo]

  The aim of this study was to evaluate the chromatin packing and sperm head morphometry of cryopreserved semen of Nelore bulls (Bos taurus indicus) of different ages. Furthermore, the influence of the degree of chromatin ...

• Melatonin regulates angiogenic and inflammatory proteins in MDA-MB-231 cell line and in co-culture with cancer-associated fibroblasts 

  Maschio-Signorini, Larissa B. ; Gelaleti, Gabriela B.; Moschetta, Marina G.; Borin, Thaiz F.; Jardim-Perassi, Bruna V.; Lopes, Juliana R. ; Lacerda, Jessica Z. ; Roela, Rosimeire A.; Bordin, Newton A.; Corr�a, Lizandra A. et al. (Mini-Reviews in Medicinal Chemistry, 2016) [Artigo]

  Background: Cancer-associated fibroblast (CAFs) are the most abundant cells in the tumor microenvironment, able to secrete growth factors and act on tumor progression. Melatonin is associated with several mechanisms of ...

• Gene-gene interactions in the NAMPT pathway, plasma visfatin/NAMPT levels, and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy 

  Luizon, M. R.; Palei, A. C.T.; Belo, V. A.; Amaral, L. M.; Lacchini, R.; Duarte, G.; Cavalli, R. C.; Sandrim, V. C. ; Tanus-Santos, J. E. (Pharmacogenomics Journal, 2017) [Artigo]

  Nicotinamide phosphorybosil transferase (NAMPT) polymorphisms affect visfatin/NAMPT levels and may affect the responsiveness to therapy in hypertensive disorders of pregnancy. We examined whether NAMPT polymorphisms ...

• Plasma levels of increased miR-195-5p correlates with the sFLT-1 levels in preeclampsia 

  Sandrim, Valeria Cristina ; Eleuterio, Nibia ; Pilan, Eliane ; Tanus-Santos, Jose Eduardo; Fernandes, Karla; Cavalli, Ricardo (Hypertension in Pregnancy, 2016) [Artigo]

  Although the role of soluble fms-like tyrosine kinase 1 (sFLT-1) in preeclampsia is well-established, the mechanism related to its synthesis remains poorly understood. We evaluated the association among the circulating ...

• Invasive tests in pregnancy 

  Roscani, Meliza G.oi; Zanati, Silmeia G.; Salmazo, Pericles S.; Carvalho, Fabio C.; Magalhães, Claudia G.; Borges, Vera T.herezinha M; Matsubara, Beatriz B.; Hueb, João C (Clinics (São Paulo, Brazil), 2014) [Nota]

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