• Thimet Oligopeptidase (EC 3.4.24.15) Key Functions Suggested by Knockout Mice Phenotype Characterization 

  Santos, Nilton B Dos; Franco, Roseane D.; Camarini, Rosana; Munhoz, Carolina D.; Eichler, Rosangela A S; Gewehr, Mayara C F; Reckziegel, Patricia; Llanos, Ricardo P.; Dale, Camila S.; Silva, Victoria R O da et al. (Biomolecules, 2019) [Artigo]

  Thimet oligopeptidase (THOP1) is thought to be involved in neuropeptide metabolism, antigen presentation, neurodegeneration, and cancer. Herein, the generation of THOP1 C57BL/6 knockout mice (THOP1-/-) is described showing ...

• Canine neutrophils cooperate with macrophages in the early stages of Leishmania infantum in vitro infection 

  Pereira, Maria A.; Alexandre-Pires, Graça; Câmara, Margarida; Santos, Marcos; Martins, Catarina; Rodrigues, Armanda; Adriana, Jéssica; Passero, Luiz Felipe D. ; Pereira da Fonseca, Isabel; Santos-Gomes, Gabriela (Parasite Immunology, 2019) [Artigo]

  Leishmania infantum is the aetiological agent of human visceral leishmaniasis and canine leishmaniasis, both systemic and potentially fatal diseases. Polymorphonuclear neutrophils (PMN) are the first cells to phagocyte ...

• Hierarchical assessment of host factors influencing the spontaneous resolution of hepatitis C infection 

  Provazzi, Paola Jocelan Scarin ; Rossi, Livia Maria Gonçalves ; Carneiro, Bruno Moreira ; Miura, Valeria Chamas ; Rosa, Plinio Cesar Rodrigues ; de Carvalho, Lucas Rodrigues ; de Andrade, Stephane Tereza Queiroz ; Fachini, Roberta Maria; Grotto, Rejane Maria Tommasini ; Silva, Giovanni Faria et al. (Brazilian Journal of Microbiology, 2019) [Artigo]

  Background: Hepatitis C virus (HCV) infection is associated with chronic liver disease, resulting in cirrhosis and hepatocellular carcinoma. Approximately 20% of HCV infections are spontaneously resolved. Here, we assessed ...

• Adipogenic differentiation of murine bone marrow mesenchymal stem cells induced by visible light via photo- induced biomodulation 

  Castilho-Fernandes, Andrielle; Lopes, Tácila G.; Ferreira, Fernanda U.; Rezende, Nayara; Silva, Valéria F.; Primo, Fernando L. ; Fontes, Aparecida Maria; Ribeiro-Silva, Alfredo; Tedesco, Antonio Claudio (Photodiagnosis and Photodynamic Therapy, 2019) [Artigo]

  Background: Bone marrow mesenchymal stem cells (BM-MSCs) are undifferentiated cells that can proliferate and differentiate into specialized cells for tissue self-repair. Low-level laser (LLL) can induce biomodulatory effects ...

• Flexor tendon injury: Avascular or vascularized region suture? Biomechanical and histopathological study in rabbits 

  Sardenberg, Trajano ; Muller, Sergio Swain ; Coelho, Kunie Iabuk Rabello ; Varanda, Denis ; Cortopassi, Andrea Christina ; Pereira, Gilberto José Cação (Revista Brasileira de Ortopedia, 2019) [Artigo]

  Objectives To analyze the mechanical and histopathological aspects of flexor tendon healing with interest on the site of the placement of the suture, either in the vascular or in the avascular region. Methods A total of ...

• Impact of gestational low protein diet and postnatal bisphenol A exposure on chemically induced mammary carcinogenesis in female offspring rats 

  Varuzza, Muriele B. ; Zapaterini, Joyce R. ; Colombelli, Ketlin T. ; Barquilha, Caroline N. ; Justulin, Luis A. ; Muñoz-de-Toro, Monica; Kass, Laura; Barbisan, Luis F. (Environmental Toxicology, 2019) [Artigo]

  This study evaluated the effect of gestational low protein diet (LPD) and/or postnatal bisphenol A (BPA) exposure on mammary gland development and carcinogenesis in female offspring. Pregnant Sprague-Dawley rats were fed ...

• Dexamethasone induces primary amnion epithelial cell senescence through telomere-P21 associated pathway† 

  Martin, Laura F. ; Richardson, Lauren S.; da Silva, Márcia Guimarães ; Sheller-Miller, Samantha; Menon, Ramkumar (Biology of reproduction, 2019) [Artigo]

  Dexamethasone (Dex), a corticosteroid hormone, is used during the perinatal period to help fetal lung and other organ development. Conversely, Dex-induced cell proliferation has been associated with accelerated aging. Using ...

• Is breath testing without 13C-labelled external urea able to detect Helicobacter pylori infection? 

  Carlos, Ana Beatriz Marques ; de Oliveira, Cássio Vieira ; Rodrigues, Maria Aparecida Marchesan ; Costa, Vladimir Eliodoro (Analytical and Bioanalytical Chemistry, 2019) [Artigo]

  Helicobacter pylori (H. pylori) infection is the main cause of gastric inflammation and peptic ulcer disease. Diagnosis and treatment are important to prevent these outcomes. The diagnosis of H. pylori infection can be ...

• The comet assay in Ceraeochrysa claveri (Neuroptera: Chrysopidae): A suitable approach for detecting somatic and germ cell genotoxicity induced by agrochemicals 

  Gastelbondo-Pastrana, Bertha Irina ; Fernandes, Fábio Henrique ; Salvadori, Daisy Maria Fávero ; Santos, Daniela Carvalho dos (Chemosphere, 2019) [Artigo]

  Some agrochemicals are genotoxic to several organisms. Nevertheless, few protocols are currently available for measuring the toxicogenetic effects of these compounds in target and non-target field-collected species of ...

• Isolation and molecular characterization of spermatogonia from male Sprague-Dawley rats exposed in utero and postnatally to dibutyl phthalate or acrylamide 

  Souza, Nathália P. ; Arnold, Lora L.; Pennington, Karen L.; Nascimento e Pontes, Merielen G. ; Miot, Helio A. ; de Camargo, João Lauro V. ; Cohen, Samuel M. (Toxicology Mechanisms and Methods, 2019) [Artigo]

  The increased incidence of testicular disorders in young men and the possible influence of environmental chemicals, such as dibutyl phthalate (DBP) and acrylamide (AA), requires experimental models for identifying modes ...

• Altered maternal metabolism during mild gestational hyperglycemia as a predictor of adverse perinatal outcomes: A comprehensive analysis 

  Rudge, Marilza Vieira Cunha ; Barbosa, Angélica Mercia Pascon ; Sobrevia, Luis ; Gelaleti, Rafael Bottaro ; Hallur, Raghavendra Lakshmana Shetty ; Marcondes, João Paulo Castro ; Salvadori, Daisy Maria Fávero ; Prudêncio, Caroline Baldini ; Magalhães, Claudia Garcia ; Costa, Roberto et al. (Biochimica et Biophysica Acta - Molecular Basis of Disease, 2019) [Resenha]

  Mild gestational hyperglycemia (MGH), as assessed using the normal oral glucose tolerance test (OGTT) and detection of an altered glycemic profile, is associated with adverse perinatal outcome. This study described the ...

• Drinking for protection? Epidemiological and experimental evidence on the beneficial effects of coffee or major coffee compounds against gastrointestinal and liver carcinogenesis 

  Romualdo, Guilherme Ribeiro ; Rocha, Ariane Bartolomeu ; Vinken, Mathieu; Cogliati, Bruno; Moreno, Fernando Salvador; Chaves, María Angel García; Barbisan, Luis Fernando (Food Research International, 2019) [Resenha]

  Recent meta-analyses indicate that coffee consumption reduces the risk for digestive tract (oral, esophageal, gastric and colorectal)and, especially, liver cancer. Coffee bean-derived beverages, as the widely-consumed ...

• Isolation, cultivation and immunofluorescence characterization of lamellar keratinocytes from equine hoof by using explants 

  Pfeifer, João P.H. ; Santos, Vitor H. ; Rosa, Gustavo ; Souza, Jaqueline B. ; Watanabe, Marcos Jun ; Fonseca-Alves, Carlos E. ; Deffune, Elenice ; Alves, Ana L.G. (Pesquisa Veterinaria Brasileira, 2019) [Artigo]

  The importance of the hoof to the horse health is clear, and the current knowledge regarding the cellular aspects of hoof keratinocytes is poor. Studies on equine keratinocyte culture are scarce. Developing keratinocyte ...

• Fragmented Fat: A new method for harvesting and processing of lipograft 

  Mendes, Flavio Henrique ; Viterbo, Fausto ; Deffunne, Elenice ; Domingues, Maria Aparecida Custódio ; Golim, Marjorie Assis ; Gabas, José Marcos ; Rossoni, Renan ; Nunes, Helga Caputo (Journal of Plastic, Reconstructive and Aesthetic Surgery, 2019) [Carta]

• Elevated prevalence of high-risk HPV in healthy oral mucosa of users and nonusers of drugs in Northeastern Brazil 

  Ribeiro, Mariana Goveia Melo; Marcolino, Larissa Doddi ; Ramos, Bruna Ribeiro de Andrade ; Trento, Cleverson Luciano; Araujo, Karina Conceição Gomes Machado de; Silva, José Rodrigo Santos; Jain, Sona; Gurgel, Ricardo Queiroz; Silva, Márcia Guimarães ; Dolabella, Silvio Santana (Brazilian oral research, 2019) [Artigo]

  Variable rates of HPV infection have been reported in healthy oral mucosa worldwide. The main objective of this study was to detect and genotype HPV infection in users and nonusers of drugs with clinically healthy mucosa ...

• Experimental cryptorchidism enhances testicular susceptibility to dibutyl phthalate or acrylamide in Sprague-Dawley rats 

  de Souza, N. P. ; Cardoso, AP Ferragut ; Gomide, L. M.M. ; Lima, T. R.R. ; Miot, H. A. ; Martino-Andrade, A. J.; Arnold, L. L.; Pennington, K. L.; Cohen, S. M.; de Camargo, J. L.V. et al. (Human and Experimental Toxicology, 2019) [Artigo]

  Cryptorchidism (CPT), the most common male congenital abnormality, is variably associated with other male reproductive tract problems. We evaluated if cryptorchid rats develop enhanced testicular susceptibility to dibutyl ...

• Barium Enema Revisited in the Workup for the Diagnosis of Hirschsprung's Disease 

  Lourenção, Pedro Luiz Toledo de Arruda; Valerini, Felipe Gilberto; Cataneo, Antonio Jose Maria; Ortolan, Erika Veruska Paiva; Silveira, Guilherme Lopes da ; Piva, Mariana Floriano Luiza; Cucco, Lucas da Matta; Rodrigues, Maria Aparecida Marchesan (Journal of pediatric gastroenterology and nutrition, 2019) [Artigo]

  OBJECTIVE: To analyse the diagnostic capacity of barium enema (BE) in the diagnostic investigation for Hirschsprung's disease (HD) was analyzed for transition zone (TZ) identification and rectosigmoid index (RSI) ≤1.0 ...

• Paracoccidioidomycosis 

  Franco, Marcello ; da Silva Lacaz, Carlos; Restrepo-Moreno, Angela; Del Negro, Gildo (Paracoccidioidomycosis, 2018) [Livro]

  Paracoccidioidomycosis continues to be a serious health problem among rural workers in many Latin American countries. This deep mycosis has many similarities to other deep mycoses that affect the developed world. Furthermore, ...

• Experimental paracoccidioidomycosis 

  Coelho, Kunie Iabuki Rabello ; Defaveri, Julio ; Rezkallah-Iwasso, Maria Thereza ; Peraçoli, Maria Terezinha S. (Paracoccidioidomycosis, 2018) [Capítulo de livro]

  Paracoccidioidomycosis seems to be primarily a disease of man, in whom it runs a variable course and often with prolonged periods of incubation. Hamsters were introduced as experimental animals for the study of ...

• Preface 

  Franco, Marcello ; Da Silva Lacaz, Carlos; Restrepo-Moreno, Angela; Del Negro, Gildo (Paracoccidioidomycosis, 2018) [Editorial]

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