RSS 1.0Departamento de Patologia
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Histopathological features of thrombotic microangiopathies in renal biopsies
Neto, Miguel Ernandes
; Soler, Lucas de Moraes ; Vasconcelos, Halita Vieira Gallindo ; Dos Santos, Daniela Cristina ; Viero, Rosa Marlene ; de Andrade, Luís Gustavo Modelli (Journal of Nephropathology, 2019) [Artigo]
Background: Thrombotic microangiopathy (TMA) is a morphologic lesion characterized by thrombi occluding microvasculature related to endothelial injury. Objectives: This study aimed to assess the association between ... -
Pyogenic granuloma secondary to a pterygium
(Journal Francais d'Ophtalmologie, 2022) [Carta] -
Neural Infection by Oropouche Virus in Adult Human Brain Slices Induces an Inflammatory and Toxic Response
(Frontiers in Neuroscience, 2021) [Artigo]Oropouche virus (OROV) is an emerging arbovirus in South and Central Americas with high spreading potential. OROV infection has been associated with neurological complications and OROV genomic RNA has been detected in ... -
Decreasing sperm quality in mice subjected to chronic cannabidiol exposure: New insights of cannabidiol-mediated male reproductive toxicity
(Chemico-Biological Interactions, 2022) [Artigo]Cannabidiol (CBD) is a natural cannabinoid present in the Cannabis sativa plant, widely prescribed as an anticonvulsant drug, especially for pediatric use. However, its effects on male reproduction are still little ... -
Pulmonary Neuroendocrine Neoplasms Overexpressing Epithelial-Mesenchymal Transition Mechanical Barriers Genes Lack Immune-Suppressive Response and Present an Increased Risk of Metastasis
; ; Machado-Rugolo, Juliana; ; ; ; ; ; ; et al. (Frontiers in Oncology, 2021) [Artigo]
Typical carcinoids (TC), atypical carcinoids (AC), large cell neuroendocrine carcinomas (LCNEC), and small cell lung carcinomas (SCLC) encompass a bimodal spectrum of metastatic tumors with morphological, histological and ... -
In Situ Overexpression of Matricellular Mechanical Proteins Demands Functional Immune Signature and Mitigates Non-Small Cell Lung Cancer Progression
; ; ; Machado-Rugolo, Juliana; ; ; ; ; ; et al. (Frontiers in Immunology, 2021) [Artigo]
Non-small cell lung carcinoma (NSCLC) is a complex cancer biome composed of malignant cells embedded in a sophisticated tumor microenvironment (TME) combined with different initiating cell types, including immune cells and ... -
Obesity-induced dysbiosis exacerbates ifn-γ production and pulmonary inflammation in the mycobacterium tuberculosis infection
(Cells, 2021) [Artigo]The microbiota of the gut–lung axis affects local and far-reaching immune responses and might also trigger chronic and inflammatory diseases. We hypothesized that gut dysbiosis induced by obesity, which coexists in countries ... -
Chromoblastomycosis evolving to sarcomatoid squamous cell carcinoma: A case report
; ; ; Passero, Luiz Felipe Domingues (Dermatology Reports, 2021) [Artigo]
Chromoblastomycosis (CMB) is a cutaneous fungal infection caused by dematiaceous fungi. According to the World Health Organization CMB has been elected as a tropical disease, and it is prevalent in tropical and subtropical ... -
Managing chromoblastomycosis with acitretin plus imiquimod: A case report on the improvement of cutaneous lesions and reduction of the treatment time
; ; ; Passero, Luiz Felipe Domingues (Journal of Dermatology, 2021) [Artigo]
Chromoblastomycosis (CBM) is an infectious disease caused by fungi that is prevalent in tropical and subtropical countries. Besides few therapeutic options, the classical treatment of CBM needs to be administrated for a ... -
The Fibrosis-Targeted Collagen/Integrins Gene Profile Predicts Risk of Metastasis in Pulmonary Neuroendocrine Neoplasms
; Machado-Rugolo, Juliana; ; ; ; ; (Frontiers in Oncology, 2021) [Artigo]
Recently, collagen/integrin genes have shown promise as predictors of metastasis mainly in non-small cell lung cancer and breast cancer. However, it is unknown if these gene expression profiling differ in metastatic potential ... -
A case of tuberculosis verrucosa cutis in Brazil undiagnosed for 15 years
; Passero, Luiz Felipe Domingues; ; (Brazilian Journal of Infectious Diseases, 2021) [Artigo]
Tuberculosis verrucosa cutis is a rare medical condition that is caused by the inoculation of Mycobacterium tuberculosis into the skin of a previously sensitized individual. This clinical form of tuberculosis corresponds ... -
Abnormal long non-coding rnas expression patterns have the potential ability for predicting survival and treatment response in breast cancer
; ; ; Machado-Rugolo, Juliana; ; (Genes, 2021) [Artigo]
Abnormal long non-coding RNAs (lncRNAs) expression has been documented to have oncogene or tumor suppressor functions in the development and progression of cancer, emerging as promising independent biomarkers for molecular ... -
Evaluation of the diaphragm muscle remodeling, inflammation, oxidative stress and vascularization in smokers: An autopsy study
; ; ; ; ; Anaruma, Carlos Alberto; ; ; ; (Cellular Physiology and Biochemistry, 2020) [Artigo]
Background/Aims: Cigarette smoking is a key factor in systemic inflammation and oxidative stress, and it has also been associated with the loss of muscle strength and an elevated risk of pulmonary diseases. Thus, this study ... -
Cigarette smoking impairs the diaphragm muscle structure of patients without respiratory pathologies: An autopsy study
; ; ; ; ; ; Anaruma, Carlos Alberto; (Cellular Physiology and Biochemistry, 2019) [Artigo]
Background/Aims: Smoking is a major risk factor for several cardiovascular and pulmonary diseases, and it has also been associated with the loss of skeletal muscle mass and strength leading to sarcopenia. The aim of this ... -
Expression signatures of DNA repair genes correlate with survival prognosis of astrocytoma patients
(Tumor Biology, 2017) [Artigo]Astrocytomas are the most common primary brain tumors. They are very resistant to therapies and usually progress rapidly to high-grade lesions. Here, we investigated the potential role of DNA repair genes in astrocytoma ... -
A comparative histopathological, immunological, and biochemical study of experimental intravenous paracoccidioidomycosis induced in mice by three paracoccidioides brasiliensis isolates
(Medical Mycology, 1986) [Artigo]We carried out a comparative study of the histopathology (lung, liver, spleen, kidney and adrenals) and the anti-P. brasiliensis humoral (immunodiffusion test) and cellular (footpad test) immune response of mice intravenously ... -
Expression of Ki-67 antigen and caspase-3 protein in benign lesions and esophageal carcinoma
Bellini, Marilanda Ferreira; ; Silva, Ana Elizabete (Anticancer Research, 2010) [Artigo]
Background: The present study aimed to evaluate apoptosis and cell proliferation alterations in esophageal benign lesions in comparison to esophageal carcinomas. Materials and Methods: Immunohistochemistry was performed ... -
Extraocular muscle fixation to porous polyethylene orbital implants using 2-octyl-cyanoacrylate
Ferraz, Lucieni Cristina Barbarini; Schellini, Silvana A. ; ; Padovani, Carlos R. ; ; Mueller, Sergio (European Journal of Ophthalmology, 2009) [Artigo]
Purpose. To evaluate the efficacy of bioadhesive in attaching the extraocular muscles to porous polyethylene spheres in rabbit enucleated cavities. Methods. A prospective, experimental study was performed. Eight adult New ... -
Bcl-2 and bax Expressions in pre-term, term and post-term placentas
; ; ; ; ; Bevilacqua, Estela B. (American Journal of Reproductive Immunology, 2008) [Artigo]
Problem: Placental apoptosis-associated protein imbalance might contribute to the pathogenesis of pre- and post-term birth. Therefore, we evaluated the expression and distribution of pro-apoptotic (Bax) and anti-apoptotic ...