RSS 1.0Departamento de Patologia
Browse by
Recent Submissions
-
In vitro toxicogenomic activity of an MTA/salicylate-based endodontic sealer
Leme, Kamila Sauer Veiga
; Salvadori, Daisy Maria Fávero (Toxicology Reports, 2022) [Artigo]
This study was designed to investigate whether mineral trioxide aggregate (MTA) Fillapex®, an MTA/salicylate-based endodontic sealer, exerts cytotoxic and toxicogenomic effects on human gingival fibroblasts (HGFs). HGFs ... -
Dissecting and Reconstructing Matrix in Malignant Mesothelioma Through Histocell-Histochemistry Gradients for Clinical Applications
; ; ; Machado-Rugolo, Juliana; ; ; ; ; ; et al. (Frontiers in Medicine, 2022) [Artigo]
Background: Malignant pleural mesotheliomas (MM) are known for their heterogenous histology and clinical behavior. MM histology reveals three major tumor cell populations: epithelioid, sarcomatoid, and biphasic. Using a ... -
Glibenclamide Increases Nitric Oxide Levels and Decreases Oxidative Stress in an In Vitro Model of Preeclampsia
Nunes, Priscila Rezeck; Bueno Pereira, Thaina Omia ; Bertozzi Matheus, Mariana ; Grandini, Nubia Alves ; Siqueira, Juliana Silva ; Correa, Camila Renata ; Abbade, Joelcio Francisco ; Sandrim, Valeria Cristina (Antioxidants, 2022) [Artigo]
(1) Background: The bioavailability of nitric oxide (NO) and oxidative stress are important events related to the pathophysiology of preeclampsia (PE). In this present study, we aimed to evaluate the antioxidant effect of ... -
EGFL7 expression profile in IDH-wildtype glioblastomas is associated with poor patient outcome
; ; ; Goncalves, Paola Gyuliane; De Oliveira, Cristiane ; ; ; ; ; Bidinotto, Lucas Tadeu (Journal of Pathology and Translational Medicine, 2022) [Artigo]
Background: Despite the advances in glioblastoma (GBM) treatment, the average life span of patients is 14 months. Therefore, it is urgent to identity biomarkers of prognosis, treatment response, or development of novel ... -
Doxycycline Attenuates Doxorubicin-Induced Cardiotoxicity by Improving Myocardial Energy Metabolism in Rats
Dantas, Danielle; Pereira, Amanda Gomes ; Fujimori, Anderson Seiji Soares ; Ribeiro, Ana Paula Dantas ; de Almeida Silva, Carol Cristina Vágula ; Monte, Marina Gaiato ; Corrêa, Camila Renata ; Fernandes, Ana Angélica ; Bazan, Silmeia Garcia Zanati ; Azevedo, Paula Schmidt et al. (Journal of Cardiovascular Development and Disease, 2022) [Artigo]
Aim: Evaluate the influence of doxycycline, an anti-inflammatory and matrix metalloproteinase (MMP) inhibitor, on the attenuation of chronic doxorubicin-induced cardiotoxicity in rats. Methods: We allocated male Wistar ... -
Effect of probiotic supplementation on plasma metabolite profile after Roux-Y gastric bypass: a prospective, randomized, double-blind, placebo-controlled clinical trial
; Felicidade, Ingrid; ; ; ; ; Ribeiro, Lúcia Regina ; ; ; et al. (International Journal of Obesity, 2022) [Artigo]
Background/objective: There is evidence that metabolic profile changes after Roux-Y gastric bypass (RYGB), especially due to modifications in the gastrointestinal tract. In addition, previous studies have suggested that ... -
Agreement between histopathological and intraoperative classifications for pediatric appendicitis and its relationship with the post-operative clinical outcome
Silva, Camila de Paula; Ortolan, Erika Veruska Paiva ; Ribeiro, Sergio Marrone ; Tedesco, Bruna Aliotto Nalin ; Terra, Simone Antunes ; Rodrigues, Maria Aparecida Marchesan ; Lourenção, Pedro Luiz Toledo de Arruda (Frontiers in Pediatrics, 2022) [Artigo]
Introduction: Some studies have shown poor agreement between intraoperative and histopathological classifications for appendicitis, despite their routine use in clinical practice. Objective: To investigate the agreement ... -
Are isothiocyanates and polyphenols from Brassicaceae vegetables emerging as preventive/therapeutic strategies for NAFLD? The landscape of recent preclinical findings
Bacil, Gabriel P.; ; ; Barbisan, Luís Fernando ; Romualdo, Guilherme R. (Food and Function, 2022) [Resenha]
Nonalcoholic fatty liver disease (NAFLD) is a lipid impairment-related chronic metabolic disease that affects almost 25% of the worldwide population and has become the leading cause of liver transplantation in the United ... -
Is micronucleus assay in oral exfoliated cells a useful biomarker for biomonitoring populations exposed to pesticides? A systematic review with meta-analysis
; ; ; ; ; ; Salvadori, Daisy Maria Favero; (Environmental Science and Pollution Research, 2022) [Resenha]
The systematic review (SR) with meta-analysis aimed to infer if micronucleus assay using oral mucosal cells a useful biomarker for biomonitoring populations continuously exposed to pesticides (EP). The SR has been made in ... -
Comparison of two microscopic interpretations of vaginal microbiota with molecular profiling
; ; ; ; Silva, Márcia G.; Marconi, Camila (Diagnostic Microbiology and Infectious Disease, 2022) [Artigo]
Objective: To compare the diagnosis of bacterial vaginosis (BV) by Nugent scoring criteria (Nugent-BV) and the diagnosis of BV and/or aerobic vaginitis (AV) using Donders criteria (Donders-BV/AV) for identifying Molecular-BV ... -
Testicular alterations in cryptorchid/orchiopexic rats chronically exposed to acrylamide or di-butyl-phthalate
Lima, Thania R. R.; Souza, Nathália P. ; Cardoso, Ana P. Ferragut ; Gomide, Lígia M. M. ; Pontes, Merielen G. Nascimento E. ; Miot, Hélio A. ; ; ; De Camargo, João Lauro V. (Journal of Toxicologic Pathology, 2022) [Artigo]
Exposure of Sprague-Dawley (SD) rats to acrylamide (AA) or di-butyl-phthalate (DBP) from the 12th gestational day to the 16th postnatal week (PNW) has been shown to reduce the effectiveness of orchiopexy in recovering the ... -
Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p
Bartolomeu, Ariane Rocha; Romualdo, Guilherme Ribeiro ; ; ; ; ; Barbisan, Luís Fernando (International Journal of Molecular Sciences, 2022) [Artigo]
Colorectal cancer (CRC) is one of most common cancers worldwide, with high rates of mortality. Epidemiological findings demonstrate that coffee consumption reduces the risk of developing CRC by ~13%. In general, in vivo ... -
Arthrospira (Spirulina) platensis feeding reduces the early stage of chemically-induced rat colon carcinogenesis
Amadeu, Simone Oliveira; Sarmiento-Machado, Luis Manuel ; Bartolomeu, Ariane Rocha ; ; Romualdo, Guilherme Ribeiro ; Moura, Nelci Antunes de ; Barbisan, Luis Fernando (British Journal of Nutrition, 2022) [Artigo]
Colorectal cancer is the third most diagnosed cancer worldwide and linked to dietary/lifestyle factors. Arthrospira (Spirulina) platensis (AP) contains bioactive compounds with beneficial effects in vivo/in vitro. Thus, ... -
Effects of the SGLT2 Inhibition on Cardiac Remodeling in Streptozotocin-Induced Diabetic Rats, a Model of Type 1 Diabetes Mellitus
Rosa, Camila Moreno; Campos, Dijon Henrique Salome ; Reyes, David Rafael Abreu ; Damatto, Felipe Cesar ; Kurosaki, Lucas Yamada ; Pagan, Luana Urbano ; ; Corrêa, Camila Renata ; Fernandes, Ana Angelica Henrique ; Okoshi, Marina Politi et al. (Antioxidants, 2022) [Artigo]
Clinical trials have shown that sodium glucose co-transporter 2 (SGLT2) inhibitors improve clinical outcomes in diabetes mellitus (DM) patients. As most studies were performed in Type 2 DM, the cardiovascular effects of ... -
Cervicovaginal loads of Gardnerella spp. are increased in immunocompetent women with persistent high-risk human papillomavirus infection
Belleti, Rafael; Marcolino, Larissa Doddi ; Novak, Juliano ; Ferreira, Carolina Sanitá Tafner ; Bolpetti, Aline do Nascimento ; Pinto, Gabriel Vitor da Silva ; ; Silva, Márcia Guimarães da ; Marconi, Camila (Journal of medical microbiology, 2022) [Artigo]
Introduction. Two high-oncogenic-risk human papilomavirus (hrHPV) genotypes - HPV16 and HPV18 - cause most of the cases of cervical cancer worldwide. Bacterial vaginosis is associated with increased hrHPV persistence, ... -
Septic embolism by Candida albicans
Oliveira, Cristiano Claudino; Camolese, Viviane Hellmeister ; Marques, Mariangela Esther Alencar (Revista Cubana de Medicina Tropical, 2021) [Carta]
-
Is there a relationship between preoperative cytological diagnosis and evolution in patients with differentiated thyroid carcinoma? A retrospective study
Colenci, Renato; Minicucci, Marcos Ferreira ; Soares, Carlos Segundo Paiva ; Oliveira, Cristiano Claudino de ; Marques, Mariângela Esther de Alencar ; Tagliarini, José Vicente ; Mazeto, Gláucia Maria Ferreira da Silva (Archives of Endocrinology and Metabolism, 2022) [Artigo]
Objective: Cytological analysis and Bethesda classification of thyroid nodules is the standard method of diagnosing differentiated thyroid carcinoma (DTC). However, even for nodules with a non-malignant cytological diagnosis, ... -
What enzyme-modified proteins are able to do
Fleuri, Luciana Francisco; Zanutto-Elgui, Mirella Rossitto ; Barros, Margarida Maria ; Carvalho, Pedro Luiz Pucci Figueiredo de ; Koike, Meliane Akemi ; ; Oliveira, Deilson Elgui de ; Santos, Andressa Genezini dos ; Novelli, Paula Kern (Value-Addition in Food Products and Processing Through Enzyme Technology, 2021) [Capítulo de livro]
Enzymes are proteins specialized in the catalysis of chemical reactions, and they are applied in a wide variety of industrial sectors. In this scenario, proteases hydrolyze proteins, one of the first classes of enzymes ... -
Vascular mimicry: A potential therapeutic target in breast cancer
; ; Vahedian, Vahid; ; ; ; ; ; ; et al. (Pathology Research and Practice, 2022) [Resenha]
Treating breast cancer, especially in the invasive state, is one of the challenges in treating cancer. Invasion and metastasis are factors in the failure of breast cancer treatments. One of the causes of this failure is ... -
Genital Mycoplasmas and Biomarkers of Inflammation and Their Association With Spontaneous Preterm Birth and Preterm Prelabor Rupture of Membranes: A Systematic Review and Meta-Analysis
Noda-Nicolau, Nathalia M.; ; ; Silva, Mariana C. ; Bento, Giovana F. C. ; Cursino, Geovanna C. ; ; ; ; Silva, Márcia G. et al. (Frontiers in Microbiology, 2022) [Resenha]
Genital mycoplasmas (GM), such as Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma parvum, and Ureaplasma urealyticum are commonly associated with spontaneous preterm labor (SPTL), spontaneous preterm birth (PTB), and ...