Submissões recentes

  • Bisphenol a and mesenchymal stem cells: Recent insights

    Nunes, Helga Caputo Autor UNESP; Scarano, Wellerson Rodrigo Autor UNESP; Deffune, Elenice Autor UNESP; Felisbino, Sérgio Luis Autor UNESP; Porreca, Immacolata; Delella, Flávia Karina Autor UNESP (Life Sciences, 2018) [Resenha]
    Mesenchymal stem cells (MSCs) are found in all adult mesenchymal tissues. They play a role in the maintenance of tissue homeostasis and repair by allowing renewal of the cellular stock. MSCs can be isolated from both human ...
  • Multiple Tolerization Reduces Antibody Binding Against Tolerogen Cells: Implications for the Production of Monoclonal Antibodies

    De Almeida, Rodrigo Autor UNESP; Nakamura, Cecília Naomi Autor UNESP; De Lima Fontes, Marina Autor UNESP; Da Silva, Julia Paiola Autor UNESP; Bertanha, Matheus Autor UNESP; Deffune, Elenice Autor UNESP; Fusco-Almeida, Ana Marisa Autor UNESP; Moroz, Andrei Autor UNESP (Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2018) [Artigo]
    We report an immunization technique that can update the production of monoclonal antibodies (mAbs): the multiple tolerization subtractive immunization (MTSI). A total of 10 BALB/C mice were used. Animals in group 1 received ...
  • Association of UGT2B7, UGT1A9, ABCG2, and IL23R polymorphisms with rejection risk in kidney transplant patients

    Cilião, Heloísa Lizotti; Camargo-Godoy, Rossana Batista Oliveira; de Souza, Marilesia Ferreira; dos Reis, Mariana Bisarro Autor UNESP; Iastrenski, Lorena; Alvares Delfino, Vinicius Daher; Rogatto, Silvia Regina Autor UNESP; de Syllos Cólus, Ilce Mara (Journal of Toxicology and Environmental Health - Part A: Current Issues, 2017) [Artigo]
    Despite advances in testing compatibility between donor and recipient, graft rejection remains a current concern. Single-nucleotide polymorphisms (SNPs) that codify altered enzymes of metabolism, drug transport, and the ...
  • Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors

    Bisarro Dos Reis, Mariana; Barros-Filho, Mateus Camargo; Marchi, Fábio Albuquerque; Beltrami, Caroline Moraes; Kuasne, Hellen; Pinto, Clóvis Antônio Lopes; Ambatipudi, Srikant; Herceg, Zdenko; Kowalski, Luiz Paulo; Rogatto, Silvia Regina (The Journal of clinical endocrinology and metabolism, 2017) [Artigo]
    Context: Even though the majority of well-differentiated thyroid carcinoma (WDTC) is indolent, a number of cases display an aggressive behavior. Cumulative evidence suggests that the deregulation of DNA methylation has the ...
  • Nuclear loss and cytoplasmic expression of androgen receptor in penile carcinomas: role as a driver event and as a prognosis factor

    Kuasne, Hellen Autor UNESP; Barros-Filho, Mateus C.; Marchi, Fábio A.; Drigo, Sandra A. Autor UNESP; Scapulatempo-Neto, Cristovam; Faria, Eliney F.; Rogatto, Silvia R. (Virchows Archiv, 2018) [Artigo]
    Androgen receptor (AR) is a member of the steroid and nuclear family receptor that acts as transcription factor. AR signaling plays pivotal role in the development and progression of prostate cancer. However, the role of ...
  • Immunosensors made with layer-by-layer films on chitosan/gold nanoparticle matrices to detect d-dimer as biomarker for venous thromboembolism

    Rodrigues, Valquiria C.; Moraes, Marli L.; Soares, Juliana C.; Soares, Andrey C.; Sanfelice, Rafaela; Deffune, Elenice Autor UNESP; Oliveira, Osvaldo N. (Bulletin of the Chemical Society of Japan, 2018) [Artigo]
    We report on immunosensors to detect D-dimer, a biomarker of venous thromboembolism, which are made with layer-bylayer (LbL) films containing immobilized anti-D-dimer monoclonal antibody alternated with a layer of chitosan/gold ...
  • Culture of mesenchymal stem cells derived from equine synovial membrane in alginate hydrogel microcapsules

    Santos, Vitor Hugo Autor UNESP; Pfeifer, João Pedro Hübbe Autor UNESP; de Souza, Jaqueline Brandão Autor UNESP; Milani, Betsabéia Heloisa Gentilha Autor UNESP; de Oliveira, Rogério Antonio Autor UNESP; Assis, Marjorie Golim Autor UNESP; Deffune, Elenice Autor UNESP; Moroz, Andrei Autor UNESP; Alves, Ana Liz Garcia Autor UNESP (BMC Veterinary Research, 2018) [Artigo]
    Background: Mesenchymal stem cells derived from the synovial membrane (MSCSM) have a greater potential for joint regeneration, besides the capacity for chondrogenic differentiation, since they are a source closer to the ...
  • Ultrastructural analysis and residual DNA evaluation of rabbit vein scaffold

    Bertanha, Matheus Autor UNESP; Sobreira, Marcone Lima Autor UNESP; Bovolato, Ana Lívia de Carvalho Autor UNESP; Rinaldi, Jaqueline de Carvalho Autor UNESP; Reis, Patricia Pintor Autor UNESP; Moroz, Andrei Autor UNESP; de Moraes, Leonardo Nazario Autor UNESP; Deffune, Elenice Autor UNESP (Acta Cirurgica Brasileira, 2017) [Artigo]
    Purpose: To investigate the ultrastructural characteristics and analysis of residual DNA in scaffold models, produced with decellularized vena cava in an experimental model with rabbits. Methods: Three groups were created ...
  • Multidimensional integrative analysis uncovers driver candidates and biomarkers in penile carcinoma

    Marchi, Fabio Albuquerque; Martins, David Correa; Barros-Filho, Mateus Camargo; Kuasne, Hellen; Busso Lopes, Ariane Fidelis; Brentani, Helena; Trindade Filho, Jose Carlos Souza Autor UNESP; Guimarães, Gustavo Cardoso; Faria, Eliney F.; Scapulatempo-Neto, Cristovam et al. (Scientific Reports, 2017) [Artigo]
    Molecular data generation and their combination in penile carcinomas (PeCa), a significant public health problem in poor and underdeveloped countries, remain virtually unexplored. An integrativemethodology combin ing ...
  • Fibrin gel versus papain gel in the healing of chronic venous ulcers: A double-blind randomized controlled trial

    de Araújo, Illymack CF Autor UNESP; Defune, Elenice Autor UNESP; Abbade, Luciana PF Autor UNESP; Miot, Hélio A Autor UNESP; Bertanha, Matheus Autor UNESP; de Carvalho, Lídia R Autor UNESP; Ferreira, Rosana R Autor UNESP; Yoshida, Winston B Autor UNESP (Phlebology, 2017) [Artigo]
    Objectives: Compare the efficacy and safety of fibrin gel to 8% papain gel for wound dressing of venous ulcers. Method: Patients with chronic venous ulcers were randomly assigned to one in three groups: Group 1—fibrin gel; ...
  • HABP2 p. G534E variant in patients with family history of thyroid and breast cancer

    Pinheiro, Maisa Autor UNESP; Drigo, Sandra Aparecida Autor UNESP; Tonhosolo, Renata; Andrade, Sonia C.S.; Marchi, Fabio Albuquerque; Jurisica, Igor; Kowalski, Luiz Paulo; Achatz, Maria Isabel; Rogatto, Silvia Regina Autor UNESP (Oncotarget, 2017) [Artigo]
    Familial Papillary Thyroid Carcinoma (PTC) has been described as a hereditary predisposition cancer syndrome associated with mutations in candidate genes including HABP2. Two of 20 probands from families with history of ...
  • An Unexpectedly High Rate of Thrombophilia Disorders in Patients with Superficial Vein Thrombosis of the Lower Extremities

    Sobreira, Marcone Lima Autor UNESP; Rogatto, Silvia Regina Autor UNESP; dos Santos, Rodrigo Mattos Autor UNESP; Santos, Izolete Thomazini Autor UNESP; Ferrari, Iracema Carvalho Autor UNESP; Yoshida, Winston Bonetti Autor UNESP (Annals of Vascular Surgery, 2017) [Artigo]
    Background Superficial vein thrombosis (SVT) is a common venous condition. Recent studies have shown that SVT is associated with high frequency of thromboembolic complications: from 22–37% for deep venous thrombosis and ...
  • A case report of venous thrombosis after kidney transplantation – We can save the graft? Time is the success factor

    Kawano, Paulo Roberto Autor UNESP; Yamamoto, Hamilto Akihissa Autor UNESP; Gerra, Rodrigo Autor UNESP; Garcia, Paula Dalsoglio Autor UNESP; Contti, Mariana Moraes Autor UNESP; Nga, Hong Si Autor UNESP; Takase, Henrique Mochida Autor UNESP; Bravin, Ariane Moyses Autor UNESP; de Andrade, Luis Gustavo Modelli Autor UNESP (International Journal of Surgery Case Reports, 2017) [Artigo]
    Introduction Venous thrombosis is a serious surgical complication that frequently results in loss of kidney graft. Case presentation We report the case of a female patient recipient of a decease kidney transplant that in ...
  • Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

    Beltrami, Caroline Moraes; dos Reis, Mariana Bisarro Autor UNESP; Barros-Filho, Mateus Camargo; Marchi, Fabio Albuquerque; Kuasne, Hellen Autor UNESP; Pinto, Clóvis Antônio Lopes; Ambatipudi, Srikant; Herceg, Zdenko; Kowalski, Luiz Paulo; Rogatto, Silvia Regina Autor UNESP (Clinical Epigenetics, 2017) [Artigo]
    Background: Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a recent increase in incidence in many countries. Although PTC has been explored by gene expression and DNA methylation studies, the regulatory ...
  • Integrative miRNA and mRNA analysis in penile carcinomas reveals markers and pathways with potential clinical impact

    Kuasne, Hellen Autor UNESP; Barros-Filho, Mateus C.; Busso-Lopes, Ariane; Marchi, Fábio A.; Pinheiro, Maisa; Muñoz, Juan J.M.; Scapulatempo-Neto, Cristovam; Faria, Eliney F.; Guimarães, Gustavo C.; Lopes, Ademar et al. (Oncotarget, 2017) [Artigo]
    Penile carcinoma (PeCa) is an important public health issue in poor and developing countries, and has only recently been explored in terms of genetic and epigenetic studies. Integrative data analysis is a powerful method ...
  • Germline large genomic alterations on 7q in patients with multiple primary cancers

    Villacis, R. A.R.; Basso, T. R.; Canto, L. M.; Nóbrega, A. F.; Achatz, M. I.; Rogatto, S. R. Autor UNESP (Scientific Reports, 2017) [Artigo]
    Patients with multiple primary cancers (MPCs) are suspected to have a hereditary cancer syndrome. However, only a small proportion may be explained by mutations in high-penetrance genes. We investigate two unrelated MPC ...
  • Genomic profile in gestational and non-gestational choriocarcinomas

    Mello, Julia Bette Homem de; Ramos Cirilo, Priscila Daniele; Michelin, Odair Carlito Autor UNESP; Custódio Domingues, Maria Aparecida Autor UNESP; Cunha Rudge, Marilza Vieira Autor UNESP; Rogatto, Silvia Regina Autor UNESP; Maestá, Izildinha Autor UNESP (Placenta, 2017) [Artigo]
    Introduction Gestational (GC) (derived from the placenta) and non-gestational (NGC) choriocarcinomas are trophoblastic diseases originated from abnormal proliferation of trophoblastic cells. These rare tumors share similar ...
  • Electrical stimulation with non-implanted electrodes for overactive bladder in adults

    Stewart, Fiona; Gameiro, Luis F. Autor UNESP; El Dib, Regina Autor UNESP; Gameiro, Monica O. Autor UNESP; Kapoor, Anil; Amaro, Joao L. Autor UNESP (Cochrane Database of Systematic Reviews, 2016) [Resenha]
    Background: Several options exist for managing overactive bladder (OAB), including electrical stimulation (ES) with non-implanted devices, conservative treatment and drugs. Electrical stimulation with non-implanted devices ...
  • Genomic copy number variation associated with clinical outcome in canine cutaneous mast cell tumors

    Jark, Paulo C Autor UNESP; Mundin, Deborah B.P.; de Carvalho, Marcio Autor UNESP; Ferioli, Raquel B. Autor UNESP; Anai, Letícia A Autor UNESP; Marchi, Fabio A.; Rogatto, Silvia R. Autor UNESP; Laufer-Amorim, Renee Autor UNESP; Tinucci-Costa, Mirela Autor UNESP (Research in Veterinary Science, 2017) [Artigo]
    Mast cell tumors are the most common malignant cutaneous tumors in dogs. Although there are several prognostic factors involved, the clinical and biological behavior of this type of tumor varies greatly, making the best ...
  • Effect of Hibiscus sabdariffa supplementation on renal function and lipidic profile in obese rats

    Melchert, Alessandra Autor UNESP; Rosa, Andressa Canuto Autor UNESP; Genari, Vanessa Autor UNESP; Frontana, Marina Salvador Gonzales Autor UNESP; Da Costa Reis, Rodrigo Prandini Autor UNESP; Guimarães Okamoto, Priscylla Tatiana Chalfun Autor UNESP; Amaro, João Luiz Autor UNESP; Rahal, Sheila Canevese Autor UNESP (Asian Journal of Animal and Veterinary Advances, 2016) [Artigo]
    Background and Objective: Obesity has emerged as a major public health problem and may be associated with chronic kidney diseases. Thus, this study aimed to evaluate the Hibiscus sabdariffa effects in the renal function ...

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