• Effects of different alcohol concentrations on the development of apical periodontitis in rats 

  Dal-Fabbro, Renan ; Marques-de-Almeida, Melyna ; Cosme-Silva, Leopoldo ; Capalbo, Letícia Cabrera ; Ervolino, Edilson ; Cintra, Luciano Tavares Angelo ; Gomes-Filho, João Eduardo (Archives of Oral Biology, 2019) [Artigo]

  Aim: To investigate the effect of different alcohol concentrations on the development of apical periodontitis (AP) in rats. Methods: Forty Wistar rats were arranged into five groups: (C) – control rats receiving sterile ...

• Targeting a ceramide double bond improves insulin resistance and hepatic steatosis 

  Chaurasia, Bhagirath; Tippetts, Trevor S.; Monibas, Rafael Mayoral; Liu, Jinqi; Li, Ying; Wang, Liping; Wilkerson, Joseph L.; Rufus Sweeney, C.; Pereira, Renato Felipe ; Sumida, Doris Hissako et al. (Science, 2019) [Artigo]

  Ceramides contribute to the lipotoxicity that underlies diabetes, hepatic steatosis, and heart disease. By genetically engineering mice, we deleted the enzyme dihydroceramide desaturase 1 (DES1), which normally inserts a ...

• Medication-related osteonecrosis of the jaws after tooth extraction in senescent female mice treated with zoledronic acid: Microtomographic, histological and immunohistochemical characterization 

  Biguetti, Claudia Cristina ; De Oliva, André Hergesel ; Healy, Kent; Mahmoud, Ramez Hassan ; Custódio, Isabela Do Carmo; Constantino, Dulce Helena; Ervolino, Edilson ; Duarte, Marco Antonio Hungaro; Fakhouri, Walid D.; Matsumoto, Mariza Akemi (PLoS ONE, 2019) [Artigo]

  Treatment with cumulative dosages of zoledronic acid (ZA) in elderly patients is a risk factor for the development of medication-related osteonecrosis of the jaws (MRONJ), mainly related to surgical triggers such as tooth ...

• Th1/Th2/Th17/Treg Balance in Apical Periodontitis of Normoglycemic and Diabetic Rats 

  Samuel, Renata Oliveira ; Ervolino, Edilson ; de Azevedo Queiroz, Índia Olinta ; Azuma, Mariane Maffei ; Ferreira, Gabriela Tiago; Cintra, Luciano Tavares Angelo (Journal of Endodontics, 2019) [Artigo]

  Introduction: The aim of this study was to evaluate the inflammatory profile of T helper (Th) cells in normoglycemic (N) and diabetic rats with apical periodontitis (AP). Methods: Twenty male Wistar rats were divided in 2 ...

• Antineoplastic agents exacerbate periodontal inflammation and aggravate experimental periodontitis 

  Gusman, David Jonathan Rodrigues ; Ervolino, Edilson ; Theodoro, Letícia Helena ; Garcia, Valdir Gouveia ; Nagata, Maria José Hitomi ; Alves, Breno Edson Sendão ; de Araujo, Nathalia Januario ; Matheus, Henrique Rinaldi ; de Almeida, Juliano Milanezi (Journal of Clinical Periodontology, 2019) [Artigo]

  Aim: This study evaluated the effects of 5-fluorouracil (5-FU) and cisplatin (CIS) in healthy periodontal tissues and in the early stages of experimental periodontitis (EP) in rats. Methods: One hundred and eighty male ...

• Influence of adjuvant therapy with green tea extract in the treatment of experimental periodontitis 

  de Almeida, Juliano Milanezi ; Marques, Bianca Mayara ; Novaes, Vivian Cristina Noronha ; de Oliveira, Fred Lucas Pinto ; Matheus, Henrique Rinaldi ; Fiorin, Luiz Guilherme ; Ervolino, Edilson (Archives of Oral Biology, 2019) [Artigo]

  Aim: This study evaluated the effects of topical green tea extract solution (GTE) as adjuvant therapy to mechanical debridement for the treatment of experimental periodontitis (EP). Material and methods: We used 120 male ...

• Bone formed after maxillary sinus floor augmentation by bone autografting with hydroxyapatite and low-level laser therapy: A randomized controlled trial with histomorphometrical and immunohistochemical analyses 

  Theodoro, Leticia Helena ; Rocha, Gustavo Spina; Ribeiro, Valmir Lucas; Sakakura, Celso Eduardo; De Mello Neto, João Martins ; Garcia, Valdir Gouveia ; Ervolino, Edilson ; Marcantonio, Elcio (Implant Dentistry, 2018) [Artigo]

  Purpose: The aim of this study was to evaluate the bone formed after maxillary sinus floor augmentation (MSFA) by bone autografting combined with hydroxyapatite (HA) that had been either treated with low-level laser therapy ...

• Influence of antimicrobial photodynamic therapy as an adjunctive to scaling and root planing on alveolar bone loss: A systematic review and meta-analysis of animal studies 

  Alberton Nuernberg, Marta Aparecida ; Janjacomo Miessi, Daniela Maria ; Ivanaga, Camila Ayumi ; Bocalon Olivo, Mariane ; Ervolino, Edilson ; Gouveia Garcia, Valdir ; Wainwright, Mark; Theodoro, Letícia Helena (Photodiagnosis and Photodynamic Therapy, 2019) [Resenha]

  Background: The study aimed to evaluate the effect of antimicrobial photodynamic therapy (aPDT) as adjunctive therapy to scaling and root planing in experimental periodontitis in rats, with or without systemic involvement, ...

• Application of Autologous Platelet-Rich Plasma on Tooth Extraction Site Prevents Occurence of Medication-Related Osteonecrosis of the Jaws in Rats 

  Toro, Luan Felipe ; de Mello-Neto, João Martins ; Santos, Fernanda Furuse Ventura dos ; Ferreira, Letícia Chaves ; Statkievicz, Cristian ; Cintra, Luciano Tavares Ângelo ; Issa, João Paulo Mardegan; Dornelles, Rita Cássia Menegati ; de Almeida, Juliano Milanezi ; Nagata, Maria José Hitomi et al. (Scientific Reports, 2019) [Artigo]

  This study evaluated the effects of local application of autologous platelet-rich plasma (PRP) on the tooth extraction site of rats presenting the main risk factors for medication-related osteonecrosis of the jaw (MRONJ). ...

• Comparative evaluation of cell viability immediately after osteotomy for implants with drills and piezosurgery: Immunohistochemistry analysis 

  Pereira, Cassiano Costa Silva ; De Souza Batista, Fábio Roberto ; Jacob, Ricardo Garcia Mureb ; Nogueira, Lamis Meorin ; De Souza Carvalho, Abrahão Cavalcante Gomes ; Gealh, Walter Cristiano ; Garcia-Júnior, Idelmo Rangel ; Okamoto, Roberta (Journal of Craniofacial Surgery, 2018) [Artigo]

  Objective: To evaluate the effect of reusing drills and piezosurgery tips during implant osteotomy on immediate bone cell viability through immunohistochemical analysis. Materials and Methods: Six male rabbits were divided ...

• Antimicrobial photodynamic therapy improves the alveolar repair process and prevents the occurrence of osteonecrosis of the jaws after tooth extraction in senile rats treated with zoledronate 

  Ervolino, Edilson ; Statkievicz, Cristian ; Toro, Luan Felipe ; de Mello-Neto, João Martins ; Cavazana, Thamires Priscila ; Issa, João Paulo Mardegan; Dornelles, Rita Cássia Menegati ; de Almeida, Juliano Milanezi ; Nagata, Maria José Hitomi ; Okamoto, Roberta et al. (Bone, 2019) [Artigo]

  This study evaluated the effects of antimicrobial photodynamic therapy (aPDT) in the alveolar repair of rats with major risk factors for bisphosphonate-related osteonecrosis of the jaws (BRONJ). Senile rats received 0.45 ...

• Oxytocin effects on osteoblastic differentiation of Bone Marrow Mesenchymal Stem Cells from adult and aging female Wistar rats 

  Santos, Leandro Figueiredo ; Singulani, Monique Patricio ; Stringhetta-Garcia, Camila Tami ; Oliveira, Sandra Helena Penha ; Chaves-Neto, Antonio Hernandes ; Dornelles, Rita Cássia Menegati (Experimental Gerontology, 2018) [Artigo]

  Recently, it has been suggested that oxytocin (OT) might play a role in the control of bone remodeling and in bone health of young and adult females. The purpose of this study was to evaluate the effect of osteogenic medium ...

• Effect of maternal periodontitis on GLUT4 and inflammatory pathway in adult offspring 

  Mattera, Maria Sara de Lima Coutinho ; Chiba, Fernando Yamamoto ; Lopes, Flávia Lombardi ; Tsosura, Thaís Verônica Saori ; Peres, Maria Angelica; Brito, Victor Gustavo Balera ; de Oliveira, Sandra Helena Penha ; Pereira, Renato Felipe ; Marani, Fernando ; Dos Santos, Rodrigo Martins et al. (Journal of periodontology, 2019) [Artigo]

  BACKGROUND: Maternal periodontal disease leads to low birth weight (LBW), insulin resistance (IR), increased TNF-α levels, and alterations in insulin signaling in adult offspring. TNF-α has been associated with the stimulation ...

• Improvement of bone repair with l-PRF and bovine bone in calvaria of rats. histometric and immunohistochemical study 

  do Lago, Eliel Scarpioni; Ferreira, Sabrina ; Garcia, Idelmo Rangel ; Okamoto, Roberta ; Mariano, Ronaldo Célio (Clinical Oral Investigations, 2019) [Artigo]

  Objectives: The effect of leucocyte- and platelet-rich fibrin (L-PRF), associated with DBBM (deproteinized bovine bone mineral; Bio-Oss®) was investigated and compared with autogenous bone graft as a standard material for ...

• Sexual maturity and fertility-related measures in young Nellore bulls receiving long-term dietary supplementation with rumen-protected polyunsaturated fatty acids 

  Rossi, Guilherme Fazan ; Ribeiro Dias, Erika Aline; Bastos, Natália Marins ; Vrisman, Dayane Priscila ; Rodrigues, Naiara Nantes ; Vantini, Roberta ; Garcia, Joaquim Mansano ; Simili, Flávia Fernanda; Ribeiro, Enilson Geraldo; Canesin, Roberta Carrilho et al. (Theriogenology, 2019) [Artigo]

  The objective of this study was to evaluate the effects of long-term supplementation with rumen-protected fatty acids (FA) on growth and reproductive parameters of young Nellore bulls in a grazing regime. Forty-eight young ...

• A putative role of teneurin-2 and its related proteins in astrocytes 

  Tessarin, Gestter W.L. ; Michalec, Ola M.; Torres-Da-Silva, Kelly R. ; Da Silva, André V. ; Cruz-Rizzolo, Roelf J. ; Gonçalves, Alaide ; Gasparini, Daniele C. ; Horta-Júnior, José A.C. ; Ervolino, Edilson ; Bittencourt, Jackson C. et al. (Frontiers in Neuroscience, 2019) [Artigo]

  Teneurins are type II transmembrane proteins comprised of four phylogenetically conserved homologs (Ten-1-4) that are highly expressed during neurogenesis. An additional bioactive peptide named teneurin C-terminal-associated ...

• Use of calcium phosphate cement for repairing bone defects: Histomorphometric and immunohistochemical analyses 

  Gulinelli, Jéssica Lemos; Queiroz, Thallita Pereira; Hochuli-Vieira, Eduardo ; Okamoto, Roberta ; Mattos, João Marcos Borges; Calcagnotto, Thiago; Dos Santos, Pâmela Leticia (Journal of Craniofacial Surgery, 2019) [Artigo]

  This study aimed to assess the repair of surgically created bone defects filled with blood clot, autogenous bone, and calcium phosphate cement, by histomorphometric and immunohistochemical analyses. Ten adult male rabbits ...

• Electroacupuncture increases immunoexpression of CB1 and CB2 receptors in experimental model of inflammatory bone loss 

  Alves, Luiza Clertiani Vieira; Lisboa, Mario Roberto Pontes; da Silveira, Helson Freitas; de Sousa, Luane Macêdo; Gusmão, Jonas Nogueira Ferreira Maciel; Dias, Diego Bernarde Souza; Ervolino, Edilson ; Furlaneto, Flávia Aparecida Chaves; Vale, Mariana Lima; Gondim, Delane Viana (Bone, 2019) [Artigo]

  This study evaluated the participation of CB1 and CB2 receptors in the antiresorptive effect of electroacupuncture (EA) on an experimental model of inflammatory bone loss in rats. 30 rats were divided into five groups: C ...

• Hyperglycemic condition influence on mineral trioxide aggregate biocompatibility and biomineralization 

  de Azevedo Queiroz, Índia O. ; Gonçalves, Luanna O. ; Takamiya, Aline S. ; Rezende, Gabriely C. ; Machado, Thiago ; Siveiri-Araujo, Gustavo ; Ervolino, Edilson ; Oliveira, Sandra H. P. ; Gomes-Filho, João E. (Journal of Biomedical Materials Research - Part B Applied Biomaterials, 2019) [Artigo]

  This study aimed to investigate in vitro and in vivo the influence of hyperglycemic condition on biocompatibility and biomineralization of gray mineral trioxide aggregate (GMTA) and white mineral trioxide aggregate (WMTA). ...

• Sitagliptin's effects on bone tissue and osseointegration in diabetic rats 

  Bautista, Cristhian Reynaldo Gomez ; Santos, Ingrid Valadares dos ; Moraes, Renata Mendonça ; Chiba, Fernando Yamamoto ; Sumida, Doris Hissako ; de Moraes, Michele Bianchi ; de Vasconcellos, Luana Marotta Reis ; Anbinder, Ana Lia (Archives of Oral Biology, 2019) [Artigo]

  Objective: To investigate the effects of sitagliptin, a dipeptidyl peptidase 4 inhibitor used to treat type II diabetes, on bone tissue and on implant osseointegration in diabetic rats. Design: Thirty-two male rats were ...

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