• Leptin: Master regulator of biological functions that affects breathing 

  Gauda, Estelle B.; Conde, Silvia; Bassi, Mirian ; Zoccal, Daniel B. ; Colombari, Debora Simoes Almeida ; Colombari, Eduardo ; Despotovic, Nikola (Comprehensive Physiology, 2020) [Artigo]

  Obesity is a global epidemic in developed countries accounting for many of the metabolic and cardiorespiratory morbidities that occur in adults. These morbidities include type 2 diabetes, sleepdisordered breathing (SDB), ...

• Reciprocal interactions between sodium appetite and need-free sugar intake 

  Santos, B. M. ; David, R. B.; Andrade, C. A.F. ; Vendramini, R. ; Hurley, S.; Menani, J. V. ; Johnson, A. K.; De Luca, L. A. (Appetite, 2020) [Artigo]

  Behavioral sensitization occurs during sodium appetite (expressed as sodium intake to compensate for depleted sodium) and need-free sodium intake (expressed as daily overnight sodium intake in excess of dietary sodium ...

• Influence of bisphosphonates on the behavior of osteoblasts seeded onto titanium discs 

  Basso, Fernanda G.; Pansani, Taisa N. ; Cardoso, Lais M. ; Hebling, Josimeri ; Real, Rodrigo Paes Vila; Costa, Carlos Alberto de Souza (Brazilian Dental Journal, 2020) [Artigo]

  Among other factors, types of bisphosphonates and treatment regimens seem to be strongly associated with the success or failure of installation of osseointegrated implants. This study investigated the influence of two ...

• Anti-hypertensive effect of hydrogen peroxide acting centrally 

  Lauar, Mariana R. ; Blanch, Graziela T.; Colombari, Débora S. A. ; Colombari, Eduardo ; De Paula, Patrícia M. ; De Luca, Laurival A. ; Menani, José V. (Hypertension Research, 2020) [Artigo]

  Intracerebroventricular (icv) injection of hydrogen peroxide (H2O2) or the increase of endogenous H2O2 centrally produced by catalase inhibition with 3-amino-1,2,4-triazole (ATZ) injected icv reduces the pressor responses ...

• Mineral preference in rats treated with muscimol into the lateral parabrachial nucleus 

  Callera, João Carlos ; De Luca, Laurival Antonio ; Menani, José Vanderlei (Neuroscience Letters, 2020) [Artigo]

  Injection of muscimol, a GABAA receptor agonist, into the lateral parabrachial nucleus (LPBN) induces 0.3 M NaCl intake in rats. In the present work, we investigated whether such an effect applies to hypertonic (0.3 M) ...

• Renovascular hypertension elevates pulmonary ventilation in rats by carotid body-dependent mechanisms 

  Melo, Mariana Rosso ; Gasparini, Silvia ; Silva, Elaine F. ; Karlen-Amarante, Marlusa ; Speretta, Guilherme F. ; Lauar, Mariana R. ; Pedrino, Gustavo R.; Menani, Jose V. ; Colombari, Debora S.A. ; Zoccal, Daniel B. et al. (American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 2020) [Artigo]

  The two kidney-one clip (2K1C) renovascular hypertension depends on the renin-angiotensin system and sympathetic overactivity. The maintenance of 2K1C hypertension also depends on inputs from the carotid bodies (CB), which ...

• Proteolytic activity, degradation, and dissolution of primary and permanent teeth 

  Scheffel, Debora Lopes Salles ; Cury, Jaime Aparecido; Tenuta, Livia Maria Andaló; Scheffel, Régis Henke; Perez, Cristina; Soares, Diana Gabriela ; Basso, Fernanda Gonçalves ; Costa, Carlos Alberto de Souza ; Pashley, David Henry; Hebling, Josimeri (International Journal of Paediatric Dentistry, 2020) [Artigo]

  Background: Primary and permanent teeth composition may influence dissolution and degradation rates. Aim: To compare the dissolution and degradation of primary and permanent teeth. Design: Enamel and dentin powders were ...

• Topical application of lectin Artin M improves wound healing in defects created in the palatal mucosa: an in vivo study in dogs 

  Kim, Yeon Jung ; de Molon, Rafael Scaf ; da Silva, Vanessa Camila; da Veiga Conrado, Marina Cavalcanti Albuquerque; Spolidório, Luis Carlos ; Roque-Barreira, Maria Cristina Antunes; Cirelli, Joni Augusto (Odontology, 2020) [Artigo]

  Previous studies have shown that topical application of lectin Artin-M accelerates wound healing in the rat oral mucosa. The aim of this study was to evaluate, by means of histology and immunohistochemistry (IHC) the effects ...

• Streptococcus mutans and actinomyces naeslundii interaction in dual-species biofilm 

  de Oliveira, Rosa Virginia Dutra ; Bonafé, Fernanda Salloume Sampaio ; Spolidorio, Denise Madalena Palomari ; Koga-ito, Cristiane Yumi ; de Farias, Aline Leite ; Kirker, Kelly R.; James, Garth A.; Brighenti, Fernanda Lourenção (Microorganisms, 2020) [Artigo]

  The study of bacterial interaction between Streptococcus mutans and Actinomyces naeslundii may disclose important features of biofilm interspecies relationships. The aim of this study was to characterize—with an emphasis ...

• Modulation of hypercapnic respiratory response by cholinergic transmission in the commissural nucleus of the solitary tract 

  Furuya, Werner I. ; Bassi, Mirian ; Menani, José V. ; Colombari, Eduardo ; Zoccal, Daniel B. ; Colombari, Débora S. A. (Pflugers Archiv European Journal of Physiology, 2020) [Artigo]

  The nucleus of the solitary tract (NTS) is an important area of the brainstem that receives and integrates afferent cardiorespiratory sensorial information, including those from arterial chemoreceptors and baroreceptors. ...

• Catalase blockade reduces the pressor response to central cholinergic activation 

  Lauar, Mariana R. ; Colombari, Débora S.A. ; Colombari, Eduardo ; De Paula, Patrícia M. ; De Luca, Laurival A. ; Menani, José V. (Brain Research Bulletin, 2019) [Artigo]

  Intracerebroventricular (icv) injection of hydrogen peroxide (H2O2), a reactive oxygen species, or the blockade of catalase (enzyme that degrades H2O2 into H2O and O2) with icv injection of 3-amino-1,2,4-triazole (ATZ) ...

• Simvastatin-Enriched Macro-Porous Chitosan-Calcium-Aluminate Scaffold for Mineralized Tissue Regeneration 

  Cassiano, Fernanda Balestrero ; Soares, Diana Gabriela; Bordini, Ester Alves Ferreira ; Anovazzi, Giovana ; Hebling, Josimeri ; Costa, Carlos Alberto de Souza (Brazilian dental journal, 2020) [Artigo]

  The present study evaluated the odontogenic potential of human dental pulp cells (HDPCs) exposed to chitosan scaffolds containing calcium aluminate (CHAlCa) associated or not with low doses of simvastatin (SV). Chitosan ...

• Biomonitoring of workers occupationally exposed to hazardous condition: the importance of genotoxicity studies 

  Cristina de Moraes Malinverni, Andrea; Maximo Prado, Carla; Roberto de Andrade, Cleverton ; Araki Ribeiro, Daniel (International Journal of Pharmacy Practice, 2020) [Carta]

• Pentoxifylline mitigates renal glycoxidative stress in obese mice by inhibiting AGE/RAGE signaling and increasing glyoxalase levels 

  Inacio, Maiara Destro ; Costa, Mariana Campos ; Lima, Tayra Ferreira Oliveira ; Figueiredo, Ingrid Delbone ; Motta, Bruno Pereira ; Spolidorio, Luís Carlos ; Assis, Renata Pires ; Brunetti, Iguatemy Lourenço ; Baviera, Amanda Martins (Life Sciences, 2020) [Artigo]

  Aim: The pharmacological properties of pentoxifylline have been re-evaluated, particularly in chronic kidney disease in diabetes, favored by its anti-inflammatory action. Definitive evidences of renal outcomes are lacking, ...

• Terpinen-4-ol and nystatin co-loaded precursor of liquid crystalline system for topical treatment of oral candidiasis 

  Francisconi, Renata Serignoli ; Maquera-Huacho, Patricia Milagros ; Tonon, Caroline Coradi ; Calixto, Giovana Maria Fioramonti ; de Cássia Orlandi Sardi, Janaína; Chorilli, Marlus ; Spolidorio, Denise Madalena Palomari (Scientific Reports, 2020) [Artigo]

  This study was performed to develop a liquid crystalline system (LCS) incorporated with terpinen-4-ol and nystatin to evaluate its antifungal, antibiofilm, and synergistic/modulatory activity against Candida albicans. The ...

• Effects of Artemisia annua alcohol extract on physiological and innate immunity of Nile tilapia (Oreochromis niloticus) to improve health status 

  Soares, Michelly Pereira ; Cardoso, Israel Luz ; Ishikawa, Márcia Mayumi; de Oliveira, Adriana da Silva Santos; Sartoratto, Adilson; Jonsson, Claudio Martin; de Queiroz, Sonia Claudia do Nascimento; Duarte, Marta Cristina Teixeira; Rantin, Francisco Tadeu ; Sampaio, Fernanda Garcia (Fish and Shellfish Immunology, 2020) [Artigo]

  Plants are a potential source of active molecules and are environmentally safer and cheaper than synthetic antibiotics. Bioactive compounds of Artemisia annua have shown pharmacological activities and are used globally as ...

• Inhibitory control of active expiration by the Bötzinger complex in rats 

  Flor, Karine C. ; Barnett, William H.; Karlen-Amarante, Marlusa ; Molkov, Yaroslav I.; Zoccal, Daniel B. (Journal of Physiology, 2020) [Artigo]

  Key points: Contraction of abdominal muscles at the end of expiration during metabolic challenges (such as hypercapnia and hypoxia) improves pulmonary ventilation. The emergence of this active expiratory pattern requires ...

• Antibiofilm efficacy of tea tree oil and of its main component terpinen-4-ol against Candida albicans 

  Francisconi, Renata Serignoli ; Huacho, Patricia Milagros Maquera ; Tonon, Caroline Coradi ; Bordini, Ester Alves Ferreira ; Correia, Marília Ferreira ; Sardi, Janaína de Cássia Orlandi; Spolidorio, Denise Madalena Palomari (Brazilian Oral Research, 2020) [Artigo]

  Candida infection is an important cause of morbidity and mortality in immunocompromised patients. The increase in its incidence has been associated with resistance to antimicrobial therapy and biofilm formation. The aim ...

• In vitro effects of photobiomodulation applied to gingival fibroblasts cultured on titanium and zirconia surfaces and exposed to LPS from Escherichia coli 

  Pansani, Taisa Nogueira ; Basso, Fernanda Gonçalves; de Souza Costa, Carlos Alberto (Lasers in Medical Science, 2020) [Artigo]

  Photobiomodulation (PBM) therapy is used to stimulate cell proliferation and metabolism, as well as reduce inflammatory cytokine synthesis, which plays a main role in the long-term stability of implants. This study assessed ...

• Antimicrobial potential, phytochemical profile, cytotoxic and genotoxic screening of sedum praealtum a. DC. (balsam) 

  Gomes Boriollo, Marcelo Fabiano; Marques, Milene Bueno; Da Silva, Thaísla Andrielle; Da Silva, Jeferson Júnior; Dias, Reigson Alves; Silva Filho, Thyago Henrique Neves; Ribeiro Melo, Isadora Letícia; Dos Santos Dias, Carlos Tadeu; De Carvalho Bernardo, Wagner Luís ; De Mello Silva Oliveira, Nelma et al. (BMC Complementary Medicine and Therapies, 2020) [Artigo]

  Background: Sedum praealtum has been used for a long time in traditional medicine as an analgesic and antiinflammatory agent. Its beneficial effects have been known since ancient times, when Latinos used it to treat sore ...

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