RSS 1.0Departamento de Fisiologia e Patologia
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In vitro antibacterial and cytotoxic activities of carvacrol and terpinen-4-ol against biofilm formation on titanium implant surfaces
Maquera-Huacho, Patricia Milagros
; Tonon, Caroline Coradi ; Correia, Marilia Ferreira ; Francisconi, Renata Serignoli ; Bordini, Ester Alves Ferreira ; Marcantonio, Élcio ; Spolidorio, Denise Madalena Palomari (Biofouling, 2018) [Artigo]
This study evaluated the antibacterial properties of carvacrol and terpinen-4-ol against Porphyromonas gingivalis and Fusobacterium nucleatum and its cytotoxic effects on fibroblast cells. The minimum inhibitory concentration ... -
A soy-based probiotic drink modulates the microbiota and reduces body weight gain in diet-induced obese mice
de Carvalho Marchesin, Juliana; Celiberto, Larissa Sbaglia ; Orlando, Allan Botinhon ; de Medeiros, Alexandra Ivo ; Pinto, Roseli Aparecida ; Zuanon, José Antônio Sampaio ; Spolidorio, Luis Carlos ; ; ; Cavallini, Daniela Cardoso Umbelino (Journal of Functional Foods, 2018) [Artigo]
This work investigates the effect of a soy-based probiotic drink (Enterococcus faecium CRL 183 and Bifidobacterium longum ATCC 15707) on the fecal microbiota composition, body weight and inflammatory parameters in diet-induced ... -
Aldosterone infusion into the 4th ventricle produces sodium appetite with baroreflex attenuation independent of renal or blood pressure changes
Gasparini, S.; Melo, M. R. ; Andrade-Franzé, G. M.F. ; ; Menani, J. V. ; Colombari, E. (Brain Research, 2018) [Artigo]
Aldosterone infusion into the 4th ventricle (4th V), upstream the nucleus of the solitary tract (NTS), produces strong 0.3 M NaCl intake. In the present study, we investigated whether aldosterone infusion into the 4th V ... -
Opioid and α2 adrenergic mechanisms are activated by GABA agonists in the lateral parabrachial nucleus to induce sodium intake
De Oliveira, Lisandra B.; Andrade, Carina A.F. ; De Luca, Laurival A. ; Colombari, Débora S.A. ; Menani, José V. (Brain Research Bulletin, 2018) [Artigo]
The activation of GABA, opioid or α2 adrenergic mechanisms in the lateral parabrachial nucleus (LPBN) facilitates hypertonic NaCl intake in rats. In the present study, we combined opioid or α2 adrenergic antagonists with ... -
Enhanced angiotensin II induced sodium appetite in renovascular hypertensive rats
Roncari, Camila F.; Barbosa, Rafaela M. ; Vendramini, Regina C. ; De Luca, Laurival A. ; Menani, José V. ; Colombari, Eduardo ; Colombari, Débora S.A. (Peptides, 2018) [Artigo]
Renovascular hypertensive 2-kidney, 1-clip (2K1C) rats have an increased activity of the renin-angiotensin system and an initial transitory increase in daily water and NaCl intake. However, the dipsogenic and natriorexigenic ... -
Bond strength and cytotoxicity of a universal adhesive according to the hybridization strategies to dentin
Leite, Maria Luísa de Alencar e Silva; Costa, Carlos Alberto de Souza ; ; ; Soares, Diana Gabriela (Brazilian Dental Journal, 2018) [Artigo]
This study evaluated application protocol (etch-and-rinse/ER and self-etching/SE) and dentin wettability (wet and dry) on microtensile bond strength (µTBS) and transdentinal cytotoxicity of Scotchbond™ Universal (SU) ... -
Influence of obesity on experimental periodontitis in rats: histopathological, histometric and immunohistochemical study
; Garcia, Valdir Gouveia; Theodoro, Letícia Helena ; Ervolino, Edilson ; ; Longo, Mariéllen ; ; ; Spolidorio, Luís Carlos ; Zuanon, José Antônio Sampaio et al. (Clinical Oral Investigations, 2018) [Artigo]
Objectives: This study assessed the influence of obesity on the progression of ligature-induced periodontitis in rats. Materials and methods: Forty-eight adult Wistar rats were randomly divided into two groups: the HL group ... -
The lateral parabrachial nucleus and central angiotensinergic mechanisms in the control of sodium intake induced by different stimuli
Roncari, Camila F.; David, Richard B. ; De Paula, Patrícia M. ; Colombari, Débora S.A. ; De Luca, Laurival A. ; Colombari, Eduardo ; Menani, José V. (Behavioural Brain Research, 2017) [Artigo]
Angiotensin II (ANG II) is a typical facilitatory stimulus for sodium appetite. Surprisingly, hyperosmolarity and central cholinergic stimulation, two classical antinatriorexigenic stimuli, also facilitate NaCl intake when ... -
Assessment of biocompatibility of ureasil-polyether hybrid membranes for future use in implantodontology
Oshiro Junior, João Augusto; Mortari, Gabriel Riquieri ; de Freitas, Rubens Moreno ; Marcantonio-Junior, Elcio ; Lopes, Leandro ; Spolidorio, Luis Carlos ; Marcantonio, Rosemary Adriana ; Chiavacci, Leila Aparecida (International Journal of Polymeric Materials and Polymeric Biomaterials, 2016) [Artigo]
The biocompatibility of ureasil-polyether hybrid materials has been tested for future application as membrane barrier. The authors evaluated ureasil-polyether hybrids membranes with different swollen behaviors: more swellable ... -
Biostimulatory effects of simvastatin on MDPC-23 odontoblast-like cells
(Brazilian oral research, 2017) [Artigo]The aim of this study was to evaluate the bioactivity and cytocompatibility of simvastatin (SV) applied to MDPC-23 odontoblast-like cells. For this purpose, MDPC-23 cells were seeded in 96-well plates and submitted to ... -
Is there correlation between polymerization shrinkage, gap formation, and void in bulk fill composites? A μCT study
(Brazilian oral research, 2017) [Artigo]This in vitro study aimed to evaluate the volume of polymerization shrinkage (VS), gap (VG), and void (VV) using computerized microtomography (μCT) in bulk fill resin composites and conventional class I restorations, and ... -
Suppressor of cytokine signaling 1 expression during LPS-induced inflammation and bone loss in rats
(Brazilian oral research, 2017) [Artigo]This study aimed to characterize the dynamics of suppressor of cytokine signaling (SOCS1) expression in a rat model of lipopolysaccharide-induced periodontitis. Wistar rats in the experimental groups were injected three ... -
Experimental osteonecrosis: development of a model in rodents administered alendronate
(Brazilian oral research, 2016) [Artigo]The main objective of this study was to cause bisphosphonate-related osteonecrosis of the jaws to develop in a rodent model. Adult male Holtzman rats were assigned to one of two experimental groups to receive alendronate ... -
A method for retrieving endodontic or atypical nonendodontic separated instruments from the root canal: a report of two cases
(The journal of contemporary dental practice, 2014) [Artigo]AIM: This clinical report presents a new method for retrieving separated instruments from the root canal with minimally invasive procedures. BACKGROUND: The presence of separated instrument in root canal may interfere in ... -
Evaluation of bone turnover after bisphosphonate withdrawal and its influence on implant osseointegration: an in vivo study in rats
; Verzola, Mario Henrique Arruda; de Molon, Rafael Scaf ; de Oliveira, Guilherme Jose Pimentel Lopes ; ; Spolidorio, Luis Carlos ; ; ; Cirelli, Joni Augusto ; Orrico, Silvana Regina Peres (Clinical Oral Investigations, 2018) [Artigo]
Objectives: The aim of this study was to investigate bone turnover alterations after alendronate (ALD) withdrawal and its influence on dental implants osseointegration. Materials and methods: Seventy female Wistar rats ... -
Polymerization shrinkage of bulk fill composites and its correlation with bond strength
; ; ; ; Magalhães, Fernando Augusto Cintra; ; (Brazilian Dental Journal, 2018) [Artigo]
The present study aimed to evaluates polymerization shrinkage (PS) using microcomputed tomography (μCT) and microtensile bond strength (μTBS) in bulk fill composites (BFC) and conventional class I restorations as well as ... -
Antimicrobial peptide-loaded liquid crystalline precursor bioadhesive system for the prevention of dental caries
Aida, Kelly Limi; Kreling, Paula Fernanda ; Caiaffa, Karina Sampaio ; Calixto, Giovana Maria Fioramonti ; Chorilli, Marlus ; Spolidorio, Denise M. P. ; Santos-Filho, Norival Alves ; Cilli, Eduardo Maffud ; Duque, Cristiane (International Journal of Nanomedicine, 2018) [Artigo]
Background: Anticaries agents must interfere with the adhesion of Streptococcus mutans and its proliferation in dental biofilm, without causing host toxicity and bacterial resistance. Natural substances, including cationic ... -
Biological Analysis of Simvastatin-releasing Chitosan Scaffold as a Cell-free System for Pulp-dentin Regeneration
; Anovazzi, Giovanna; Bordini, Ester Alves F. ; Zuta, Uxua O. ; Silva Leite, Maria Luísa A. ; Basso, Fernanda G. ; Hebling, Josimeri ; de Souza Costa, Carlos A. (Journal of Endodontics, 2018) [Artigo]
Introduction: The improvement of biomaterials capable of driving the regeneration of the pulp-dentin complex mediated by resident cells is the goal of regenerative dentistry. In the present investigation, a chitosan scaffold ... -
GABAergic contribution to the muscle mechanoreflex-mediated heart rate responses at the onset of exercise in humans
; ; ; ; ; Colombari, Eduardo; (American Journal of Physiology - Heart and Circulatory Physiology, 2018) [Artigo]
Previous studies have indicated that central GABAergic mechanisms are involved in the heart rate (HR) responses at the onset of exercise. On the basis of previous research that showed similar increases in HR during passive ... -
Photobiomodulation in the Metabolism of Lipopolysaccharides-exposed Epithelial Cells and Gingival Fibroblasts
Pansani, Taisa Nogueira; Basso, Fernanda Gonçalves ; Soares, Diana Gabriela ; ; Hebling, Josimeri ; de Souza Costa, Carlos Alberto (Photochemistry and Photobiology, 2018) [Artigo]
This study assessed the effects of photobiomodulation (PBM) to cells previously exposed to lipopolysaccharides (LPS). Human gingival fibroblasts (HGF) and epithelial cells (HaCaT) were seeded in wells of 24-well plates ...