RSS 1.0Departamento de Fisiologia e Patologia
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Role of α2-adrenoceptors in the lateral parabrachial nucleus in the control of body fluid homeostasis
Andrade, Carina Aparecida Fabricio de
; Andrade-Franzé, Glaucia Maria Fabricio de ; De Paula, PatrÍcia M. ; Luca Júnior, Laurival Antonio De ; Menani, José V. (Brazilian Journal of Medical and Biological Research, 2014) [Artigo]
Central α2-adrenoceptors and the pontine lateral parabrachial nucleus (LPBN) are involved in the control of sodium and water intake. Bilateral injections of moxonidine (α2-adrenergic/imidazoline receptor agonist) or ... -
Orientações para o uso racional de medicamentos: experiência universitária de assistência farmacêutica em ambiente público em Araraquara-SP
Melo, Mariana del Rosso de; Cruz, Fabio Cardoso ; Miguel, Tarcisotadeu ; Moreira, Raquel Regina Duarte ; Almeida, Adelia Emilia de ; Silva, Marcia da (Congresso de Extensão Universitária, 2011) [Trabalho apresentado em evento]
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Effect of light-activation on the antibacterial activity of dentin bonding agents
; Negrini, Thaís de Cássia; Spolidorio, Denise Madalena Palomari ; Hebling, Josimeri (Brazilian Journal of Oral Sciences, 2010) [Artigo]
Aim: This study evaluated the effect of light-activation on the antibacterial activity of dentin bonding systems. Methods: Inocula of Streptococcus mutans and Lactobacillus casei cultures were spread on the surface of BHI ... -
Glial cells modulate the synaptic transmission of NTS neurons sending projections to ventral medulla of Wistar rats
; Zoccal, Daniel Breseghello; ; (Physiological Reports, 2013) [Artigo]
There is evidence that sympathoexcitatory and respiratory responses to chemoreflex activation involve ventrolateral medulla-projecting nucleus tractus solitarius (NTS) neurons (NTS-VLM neurons) and also that ATP modulates ... -
Coupling between respiratory and sympathetic activities as a novel mechanism underpinning neurogenic hypertension
; Zoccal, Daniel Breseghello (Current Hypertension Reports, 2011) [Artigo]
Enhanced sympathetic outflow to the heart and resistance vessels greatly contributes to the onset and maintenance of neurogenic hypertension. There is a consensus that the development of hypertension (clinical and experimental) ... -
Hydrogen peroxide centrally attenuates hyperosmolarity-induced thirst and natriuresis
Zanella, Regis C.; Melo, Mariana Rosso ; Furuya, Werner Issao ; Colombari, Eduardo ; Menani, José V. ; Colombari, Débora Simões Almeida (Neuroscience Letters, 2016) [Artigo]
Intragastric hypertonic NaCl that simulates the ingestion of osmotically active substances by food intake induces thirst, vasopressin and oxytocin release, diuresis and natriuresis. Reactive oxygen species (ROS) produced ... -
Sodium intake, brain c-Fos protein and gastric emptying in cell-dehydrated rats treated with methysergide into the lateral parabrachial nucleus
David, Richard B.; Roncari, Camila F. ; Lauar, Mariana R. ; Vendramini, Regina C. ; ; Menani, José V. ; Luca, Laurival A. de (Physiology & Behavior, 2015) [Artigo]
Previous studies from our laboratory have shown that methysergide, a serotonergic antagonist, injected into the lateral parabrachial nucleus (LPBN) combined with a pre-load of 2 M NaCl, given by gavage, induces 0.3 M NaCl ... -
Mapping brain Fos immunoreactivity in response to water deprivation and partial rehydration: influence of sodium intake
; ; ; De Luca, Laurival A. (Physiology & Behavior, 2015) [Artigo]
Water deprivation (WD) followed by water intake to satiety, produces satiation of thirst and partial rehydration (PR). Thus, WD-PR is a natural method to differentiate thirst from sodium appetite. WD-PR also produces Fos ... -
Catecholaminergic neurons in the comissural region of the nucleus of the solitary tract modulate hyperosmolality-induced responses
Freiria-Oliveira, André H.; Blanch, Graziela T. ; ; ; ; Menani, José V. ; Colombari, Débora S. A. (American Journal Of Physiology. Regulatory, Integrative And Comparative Physiology, 2015) [Artigo]
Noradrenergic A2 neurons of the nucleus of the solitary tract (NTS) have been suggested to contribute to body fluid homeostasis and cardiovascular regulation. In the present study, we investigated the effects of lesions ... -
Transdentinal cytotoxicity of resin-based luting cements to pulp cells
Garcia, Lucas da Fonseca Roberti; Pontes, Elaine Cristina Voltolini ; Basso, Fernanda Gonçalves ; Hebling, Josimeri ; Costa, Carlos Alberto de Souza ; Soares, Diana Gabriela (Clinical Oral Investigations, 2015) [Artigo]
The aim of this study was to evaluate the transdentinal cytotoxicity of components released from different resin-based luting cements to cultured MDPC-23 odontoblast-like cells and human dental pulp cells (HDPCs). Artificial ... -
Long-term evaluation of oral gavage with periodontopathogens or ligature induction of experimental periodontal disease in mice
Molon, Rafael Scaf de; Mascarenhas, Vinicius Ibiapina ; Avila, Erica Dorigatti de ; Finoti, Livia Sertori ; Toffoli, Gustavo Boze ; Spolidorio, Denise Madalena Palomari ; Scarel-Caminaga, Raquel Mantuaneli ; ; Cirelli, Joni Augusto (Clinical Oral Investigations, 2015) [Artigo]
To evaluate in long-term periods the destruction of periodontal tissues and bacterial colonization induced by oral gavage with periodontopathogens or ligature experimental periodontal disease models. Forty-eight C57BL/6 J ... -
Porphyromonas gingivalis stimulates bone resorption by enhancing RANKL (Receptor Activator of NF-κB Ligand) through activation of toll-like receptor 2 in osteoblasts
; ; ; Souza, Pedro Paulo Chaves de; ; (The Journal Of Biological Chemistry, 2015) [Artigo]
Periodontitis has been associated with rheumatoid arthritis. In experimental arthritis, concomitant periodontitis caused by oral infection with Porphyromonas gingivalis enhances articular bone loss. The aim of this study ... -
Osteoblast differentiation is enhanced by a nano-to-micro hybrid titanium surface created by Yb:YAG laser irradiation
Mariscal-Muñoz, Eduardo; Costa, Carlos A. S. ; Tavares, Hewerson S. ; Bianchi, Jonas ; Hebling, Josimeri ; ; ; (Clinical Oral Investigations, 2015) [Artigo]
The aim of this study was to analyze the capacity of a new modified laser surface to stimulate calvarial osteoblasts isolated from neonatal mouse bones to differentiate and form mineralized nodules. Titanium discs were ... -
The long-term administration of calcineurin inhibitors decreases antioxidant enzyme activity in the rat parotid and submandibular salivary glands
Spolidorio, Luís C.; Herrera, Bruno S. ; Coimbra, Leila S. ; de Andrade, Cleverton R. ; Spolidorio, Denise M P ; Rossa Junior, Carlos ; (Life Sciences, 2015) [Artigo]
Calcineurin inhibitors are widely used for prevention of graft rejection and treatment of autoimmune disorders, which result in increased longevity and enhanced quality of life for patients. Unfortunately, the toxic side ... -
Cytocompatibility of HEMA-free resin-based luting cements according to application protocols on dentine surfaces
Soares, D. G.; ; Silva, R. H. B. Tavares da ; ; Hebling, J. ; Costa, C. A. de Souza (International Endodontic Journal, 2015) [Artigo]
To evaluate the transdentinal cytotoxicity of resin-based luting cements (RBLCs), with no HEMA in their composition, to odontoblast-like cells. Human dentine discs 0.3 mm thick were adapted to artificial pulp chambers ... -
Androgen receptors and experimental bone loss - an in vivo and in vitro study
Steffens, João Paulo; Coimbra, Leila Santana ; Rossa, Carlos ; ; ; Spolidorio, Luis Carlos (Bone, 2015) [Artigo]
Testosterone is a sex hormone that exhibits many functions beyond reproduction; one such function is the regulation of bone metabolism. The role played by androgen receptors during testosterone-mediated biological processes ... -
Clopidogrel enhances mesenchymal stem cell proliferation following periodontitis
Coimbra, L. S.; Steffens, J. P. ; ; ; Rossa, C. ; ; Spolidorio, L. C. ; (Journal Of Dental Research, 2015) [Artigo]
Bone formation is dependent on the differentiation of osteoblasts from mesenchymal stem cells (MSCs). In addition to serving as progenitors, MSCs reduce inflammation and produce factors that stimulate tissue formation. ... -
Responses of human dental pulp cells after application of a low-concentration bleaching gel to enamel
Soares, Diana G.; Basso, Fernanda G. ; Scheffel, Débora Salles ; Hebling, Josimeri ; de Souza Costa, Carlos A. (Archives Of Oral Biology, 2015) [Artigo]
To evaluate the effect of a 17.5% H2O2 gel on the odontoblastic differentiation capability of human dental pulp cells (HDPCs). The bleaching gel was applied for 45, 15 or 5min to enamel/dentine discs adapted to transwells, ... -
Facilitation of breathing by leptin effects in the central nervous system
Bassi, Miriam; Furuya, Werner Issao ; Zoccal, Daniel Breseghello ; Menani, José Vanderlei ; Colombari, Débora Simões de Almeida ; ; Colombari, Eduardo (The Journal Of Physiology, 2015) [Artigo]
With the global epidemic of obesity, breathing disorders associated with excess body weight have markedly increased. Respiratory dysfunctions caused by obesity were originally attributed to mechanical factors; however, ... -
Participation of α2 -adrenoceptors in sodium appetite inhibition during sickness behaviour following administration of lipopolysaccharide
De Luca Junior, Laurival Antonio; ; David, Richard Boarato ; Paula, Patricia Maria de ; Andrade, Carina Aparecida Fabrício de ; Menani, José Vanderlei (The Journal Of Physiology, 2015) [Artigo]
Sickness behaviour, a syndrome characterized by a general reduction in animal activity, is part of the active-phase response to fight infection. Lipopolysaccharide (LPS), an effective endotoxin to model sickness behaviour, ...