Hemoglobin (Hb) Val de Marne (Hb Footscray) in Brazil: the first case report
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Data
2016-01-01
Autores
Okumura, J. V. [UNESP]
Shimauti, E. L. T.
Silva, D. G. H. [UNESP]
Torres, L. S. [UNESP]
Belini-Junior, E. [UNESP]
Oliveira, R. G. [UNESP]
Patussi, E. V.
Herrero, J. C. M.
Bonini-Domingos, C. R. [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Funpec-editora
Resumo
Hemoglobin (Hb) variants involving alpha-chains are less common in the global population than Hb variants resulting from beta-chain alterations. Generally, alpha-chain Hb variants are caused by point mutations affecting alpha-1 and/or alpha-2 genes of the alpha-globin cluster (HBA1 and HBA2). In Brazil, the most prevalent alpha-chain Hb variant is Hb Hasharon. In this study, we present the first case of an Hb Val de Marne variant in the Americas, specifically in Brazil.
Descrição
Palavras-chave
Hemoglobin variants, Alpha-globin, HPLC
Como citar
Genetics And Molecular Research. Ribeirao Preto: Funpec-editora, v. 15, n. 2, 8 p., 2016.