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dc.contributor.authorCabrera-Martinez, Lucia V. [UNESP]
dc.contributor.authorHerrera M, L. Gerardo
dc.contributor.authorCruz-Neto, Ariovaldo P. [UNESP]
dc.date.accessioned2018-11-26T17:51:58Z
dc.date.available2018-11-26T17:51:58Z
dc.date.issued2018-06-05
dc.identifierhttp://dx.doi.org/10.7717/peerj.4627
dc.identifier.citationPeerj. London: Peerj Inc, v. 6, 13 p., 2018.
dc.identifier.issn2167-8359
dc.identifier.urihttp://hdl.handle.net/11449/164279
dc.description.abstractThe acute phase response (APR) is the first line of defense of the vertebrate immune system against pathogens. Mounting an immune response is believed to be energetically costly but direct measures of metabolic rate during immune challenges contradict this assumption. The energetic cost of APR for birds is higher than for rodents, suggesting that this response is less expensive for mammals. However, the particularly large increase in metabolic rate after APR activation for a piscivorous bat (Myotis vivesi) suggests that immune response might be unusually costly for bats. Here we quantified the energetic cost and body mass change associated with APR for the nectarivorous Pallas's long-tongued bat (Glossophaga soricina). Activation of the APR resulted in a short-term decrease in body mass and an increase in resting metabolic rate (RMR) with a total energy cost of only 2% of the total energy expenditure estimated for G. soricina. This increase in RMR was far from the large increase measured for piscivorous bats; rather, it was similar to the highest values reported for birds. Overall, our results suggest that the costs of APR for bats may vary interspecifically. Measurement of the energy cost of vertebrate immune response is limited to a few species and further work is warranted to evaluate its significance for an animal's energy budget.en
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipConselho Nacional de Pesquisa e Desenvolvimento Tecnologico
dc.description.sponsorshipDireccion General de Asuntos del Personal Academico (DGAPA)
dc.description.sponsorshipPASPA-DGAPA program of the Universidad Nacional Autonoma de Mexico
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent13
dc.language.isoeng
dc.publisherPeerj Inc
dc.relation.ispartofPeerj
dc.sourceWeb of Science
dc.subjectImmune response
dc.subjectMetabolic rate
dc.subjectCaloric cost
dc.subjectPhytohaemagglutinin
dc.subjectPhyllostomidae
dc.subjectAcute phase response
dc.subjectLipopolysacharide
dc.titleThe energetic cost of mounting an immune response for Pallas's long-tongued bat (Glossophaga soricina)en
dc.typeArtigo
dcterms.rightsHolderPeerj Inc
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniv Nacl Autonoma Mexico
dc.description.affiliationUniv Estadual Paulista, Inst Biociencias, Dept Zool, Rio Claro, SP, Brazil
dc.description.affiliationUniv Nacl Autonoma Mexico, Inst Biol, Estn Biol Chamela, San Patricio, Jalisco, Mexico
dc.description.affiliationUnespUniv Estadual Paulista, Inst Biociencias, Dept Zool, Rio Claro, SP, Brazil
dc.identifier.doi10.7717/peerj.4627
dc.identifier.wosWOS:000434235500001
dc.rights.accessRightsAcesso aberto
dc.description.sponsorshipIdCNPq: 490586/2013-9
dc.description.sponsorshipIdConselho Nacional de Pesquisa e Desenvolvimento Tecnologico: 161027/2014-8
dc.description.sponsorshipIdDireccion General de Asuntos del Personal Academico (DGAPA): IN202113
dc.description.sponsorshipIdPASPA-DGAPA program of the Universidad Nacional Autonoma de Mexico: 062-2014
dc.description.sponsorshipIdFAPESP: 2008/57687-0
dc.identifier.fileWOS000434235500001.pdf
dc.relation.ispartofsjr1,087
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