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dc.contributor.authorGuinsburg, Ruth
dc.contributor.authorBranco de Almeida, Maria Fernanda
dc.contributor.authorCastro, Junia Sampel de
dc.contributor.authorSilveira, Rita C.
dc.contributor.authorSiqueira Caldas, Jamil Pedro de
dc.contributor.authorFiori, Humberto Holmer
dc.contributor.authorVale, Marynea Silva do
dc.contributor.authorSteffen Abdallah, Vania Olivetti
dc.contributor.authorMonteiro Bigelli Cardoso, Laura Emilia
dc.contributor.authorAlves Filho, Navantino
dc.contributor.authorMoreira, Maria Elisabeth
dc.contributor.authorAcquesta, Ana Lucia
dc.contributor.authorLopes Ferrari, Ligia S.
dc.contributor.authorBentlin, Maria Regina [UNESP]
dc.contributor.authorVenzon, Paulyne Stadler
dc.contributor.authorGoncalves Ferri, Walusa Assad
dc.contributor.authorMeneses, Jucille do Amaral
dc.contributor.authorDe Albuquerque Diniz, Edna Maria
dc.contributor.authorToledo Zanardi, Dulce Maria
dc.contributor.authorDos Santos, Cristina Nunes
dc.contributor.authorBandeira Duarte, Jose Luiz
dc.contributor.authorSantiago Rego, Maria Albertina
dc.identifier.citationJournal Of Maternal-fetal & Neonatal Medicine. Abingdon: Taylor & Francis Ltd, v. 29, n. 6, p. 1005-1009, 2016.
dc.description.abstractObjective: To analyze unfavorable outcomes at hospital discharge of preterm infants born at Brazilian public university centers.Methods: Prospective cohort of 2646 inborn infants with gestational age 23-33 weeks and birth weight 400-1499g, without malformations, born at 20 centers in 2012-2013. Unfavorable outcome was defined as in-hospital death or survival at hospital discharge with 1 major morbidities: bronchopulmonary dysplasia (BPD) at 36 corrected weeks, intraventricular hemorrhage (IVH) grades 3-4, periventricular leukomalacia (PVL) or surgically treated retinopathy of prematurity (ROP).Results: Among 2646 infants, 1390 (53%) either died or survived with major morbidities: 793 (30%) died; 497 (19%) had BPD; 358 (13%) had IVH 3-4 or PVL; and 84 (3%) had ROP. Logistic regression adjusted by center showed association of unfavorable outcome with: antenatal steroids (OR 0.70; 95%CI 0.55-0.88), C-section (0.72; 0.58-0.90), gestational age <30 (4.00; 3.16-5.07), being male (1.44; 1.19-1.75), small for gestational age (2.19; 1.72-2.78), 5th-min Apgar <7 (3.89; 2.88-5.26), temperature at NICU admission <36.0 degrees C (1.42; 1.15-1.76), respiratory distress syndrome (3.87; 2.99-5.01), proven late sepsis (1.33; 1.05-1.69), necrotizing enterocolitis (3.10; 2.09-4.60) and patent ductus arteriosus (1.69; 1.37-2.09).Conclusions: More than half of the VLBW infants born at public university level 3 Brazilian hospitals either die or survive with major morbidities.en
dc.description.sponsorshipHealth Ministry of Brazil (Ministerio da Saude do Brasil)
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofJournal Of Maternal-fetal & Neonatal Medicine
dc.sourceWeb of Science
dc.subjectBronchopulmonary dysplasia
dc.subjectintraventricular hemorrhage
dc.subjectneonatal mortality
dc.subjectperiventricular leukomalacia
dc.subjectpreterm newborn infant
dc.subjectretinopathy of prematurity
dc.subjectvery low birth weight newborn infant
dc.titleDeath or survival with major morbidity in VLBW infants born at Brazilian neonatal research network centersen
dcterms.rightsHolderTaylor & Francis Ltd
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Fed Rio Grande do Sul
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionPontificia Univ Catolica Rio Grande do Sul
dc.contributor.institutionUniv Fed Maranhao
dc.contributor.institutionUniversidade Federal de Uberlândia (UFU)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionFac Ciencias Med Minas Gerais
dc.contributor.institutionFundacao Oswaldo Cruz
dc.contributor.institutionHosp Geral Pirajussara
dc.contributor.institutionUniversidade Estadual de Londrina (UEL)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniv Fed Parana
dc.contributor.institutionInst Med Integral Prof Fernando Figueira
dc.contributor.institutionHosp Estadual Sumare
dc.contributor.institutionHosp Estadual Diadema
dc.contributor.institutionUniversidade do Estado do Rio de Janeiro (UERJ)
dc.contributor.institutionUniversidade Federal de Minas Gerais (UFMG)
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, BR-01410 Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil
dc.description.affiliationUniv Estadual Campinas, Ctr Atencao Integral Saude Mulher, Hosp Mulher Prof Jose Aristodemo Pinotti, Campinas, SP, Brazil
dc.description.affiliationPontificia Univ Catolica Rio Grande do Sul, Dept Pediat, Porto Alegre, RS, Brazil
dc.description.affiliationUniv Fed Maranhao, Univ Hosp, Sao Luis, MA, Brazil
dc.description.affiliationUniv Fed Uberlandia, Fac Med, Hosp Clin, BR-38400 Uberlandia, MG, Brazil
dc.description.affiliationUniv Sao Paulo, Fac Med, Hosp Clin, Sao Paulo, SP, Brazil
dc.description.affiliationFac Ciencias Med Minas Gerais, Belo Horizonte, MG, Brazil
dc.description.affiliationFundacao Oswaldo Cruz, Inst Fernandes Figueira, Rio De Janeiro, RJ, Brazil
dc.description.affiliationHosp Geral Pirajussara, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Estadual Londrina, Univ Hosp, Londrina, PR, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Med Botucatu, Botucatu, SP, Brazil
dc.description.affiliationUniv Fed Parana, Dept Pediat, BR-80060000 Curitiba, Parana, Brazil
dc.description.affiliationUniv Sao Paulo, Fac Med Ribeirao Preto, Sao Paulo, SP, Brazil
dc.description.affiliationInst Med Integral Prof Fernando Figueira, Recife, PE, Brazil
dc.description.affiliationUniv Sao Paulo, Fac Med, Univ Hosp, Sao Paulo, SP, Brazil
dc.description.affiliationHosp Estadual Sumare, Sumare, SP, Brazil
dc.description.affiliationHosp Estadual Diadema, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Estado Rio de Janeiro, BR-20550011 Rio De Janeiro, RJ, Brazil
dc.description.affiliationUniv Fed Minas Gerais, Hosp Clin, Belo Horizonte, MG, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Med Botucatu, Botucatu, SP, Brazil
dc.rights.accessRightsAcesso aberto
dc.description.sponsorshipIdHealth Ministry of Brazil (Ministerio da Saude do Brasil): MS/VIGISUS 1755/2000
dc.description.sponsorshipIdHealth Ministry of Brazil (Ministerio da Saude do Brasil): MS/FNS 274
dc.description.sponsorshipIdHealth Ministry of Brazil (Ministerio da Saude do Brasil): FIOCRUZ/PDTSP
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