Tomographic imaging of fragmented cortical bone heteroimplant and methylmethacrylate in segmental bone defect of rabbit tibia1

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2014-01-01

Autores

De Freitas, Silvio Henrique
Dória, Renata Gebara Sampaio
De Souza Mendonça, Fábio
Dos Santos, Marcelo Diniz
Filho, Jair Rodini EngráCia [UNESP]
Vidane, AtanáSio Serafim
Marques, Alessandro Tadeu Corrêa
Ambrósio, Carlos Eduardo

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Resumo

PURPOSE: To evaluate the performance of composites consisting of fragmented cortical bone heteroimplant in association with methylmethacrylate preserved in 98% glycerin, in segmental bone defect of rabbit tibia medial metaphysis. METHODS: In this study were used twelve adult New Zealand rabbits, divided into three groups of four animals each: G30 (30 days), G60 (60 days) and G90 (90 days). The bone defects previously created in the tibia were filled with composites and both were evaluated by cone-beam computed tomography, immediately after surgery and after 30, 60, and 90 days. RESULTS: The composites fulfilled and remained in the sites of bone defects in all cases and were not registered signals of infection, migration or rejection. CONCLUSIONS: The implanted composites promoted the bone defects repair without signals of infection and/or rejection. The composites are one more option for bone defects repair.

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Biocompatible Materials, Rabbits, Tibia, Tomography

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Acta Cirurgica Brasileira, v. 29, n. 12, p. 794-800, 2014.

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