Model-based control of enzyme yield in solid-state fermentation
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Solid-state fermentation is gaining increasing importance for the production of high-added value products, for instance enzymes, from agro-industrial by-products. The main difficulty in operating this process in packed-bed bioreactors is the development of temperature and moisture gradients along the reactor length which decrease the overall productivity. In this work a practically relevant feedback control scheme is developed that allows influencing and equalizing the moisture and temperature distributions along the packed-bed bioreactor during solid-state fermentation. This prevents locally critical process conditions which may necessitate the shutdown of the operation of the bioreactor.
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distributed parameter system, drying, feedback control, heat and mass transfer, solid-state fermentation
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Procedia Engineering, v. 102, p. 362-371.
