Cancer Progression Goes Viral: The Role of Oncoviruses in Aggressiveness of Malignancies
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Data
2018-07-01
Autores
Müller-Coan, Barbara Grasiele [UNESP]
Caetano, Brunno Felipe Ramos [UNESP]
Pagano, Joseph Stephen
Elgui de Oliveira, Deilson [UNESP]
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Resumo
Cancer progression is the most relevant phase of carcinogenesis due to the development of malignant tumors in the host. Some viruses participate in malignant cell transformation, with recent compelling evidence suggesting that oncoviruses also have a role in cancer progression. The human hepatitis B (HBV) and C (HCV) viruses, human papillomaviruses (HPV), Epstein–Barr virus (EBV), and Kaposi sarcoma herpesvirus (KSHV) are the most important human oncoviruses currently known. Here, we discuss how oncoviruses can modulate cancer progression, such as tumor growth, invasion, and cancer metastasis.
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aggressive behavior, cancer progression, human oncoviruses, malignant invasion, metastasis
Como citar
Trends in Cancer, v. 4, n. 7, p. 485-498, 2018.