Phenolic isomers from plantago catharinea leaves: Isolation, identification, quantification and in vitro antioxidant activity
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Data
2017-01-01
Autores
De Souza Mesquita, Leonardo Mendes [UNESP]
Da Rocha, Claudia Quintino [UNESP]
Affonso, Luiz Henrique Lima [UNESP]
Cerulli, Antonietta
Piacente, Sonia
Tangerina, Marcelo Marucci Pereira [UNESP]
Martins, Maria Bernadete Gonçalves [UNESP]
Vilegas, Wagner [UNESP]
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Resumo
In this study we isolated two polyphenolic acids of m/z 639, called catharinol A and catharinol B, from Plantago catharinea L. (Plantaginaceae) leaves. Although presenting very similar structures, catharinol A showed higher antioxidant activity when compared with gallic acid and quercetin standards. These compounds are position isomers and present in their chemical structure the rare sugar D-allose. Molecules with similar constitution are known to have important biological activities such as antitumor and immunosuppressive. These compounds were isolated by high-performance liquid chromatography (HPLC) and characterized by mass spectrometry (FIA-ESI-IT-MS/MS) and nuclear magnetic resonance (NMR). This work is the first study on the chemical composition of P. catharinea and encourages the production of Plantago species as a good source of bioactive molecules.
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Antioxidant activity, D-allose, Plantago, Polyphenolic acids
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Natural Product Communications, v. 12, n. 3, p. 409-412, 2017.