Pharmaceutical and biomedical applications of magnetic iron-oxide nanoparticles
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Data
2017-01-01
Autores
Dussán, Kelly J. [UNESP]
Giese, Ellen C.
Vieira, Gustavo N. A. [UNESP]
Lima, Lionete N.
Silva, Debora D. V. [UNESP]
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Resumo
In the past few years, due to the rapid development of the advances in the pharmaceutical and biomedical field, the magnetic iron-oxide nanoparticles have received considerable attention for their attractive properties. Magnetic nanoparticles are perfect candidates for use in diagnosis and disease treatment because they have properties as superparamagnetic behavior, a high superficial area that allows functionalizing, biocompatibility, nanometric size (10-100 nm), low toxicity, possibility of in vivo manipulation by a low external magnetic field, and placement in a specific place. The key point of magnetic iron-oxide nanomaterials is to develop effective synthesis techniques that allow particles to have with a uniform size, high magnetic saturation, and stability, preventing aggregation and oxidation with air since these result in the loss of its magnetic properties. This chapter presents a review of various strategies to synthesis of magnetic nanoparticles and their use in pharmaceutical and biomedical field.
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Biomedical application, Magnetic iron-oxide nanoparticles, Pharmacological activity, Synthesis techniques
Como citar
Metal Nanoparticles in Pharma, p. 77-99.