• Virulence factors os Escherichia coli: An overview of human and animal infections with emphasis in bovine mastitis 

  Guerra, Simony Trevizan ; De Paula, Carolina Lechinski ; Bolaños, Carmen Alicia Daza; Hernandes, Rodrigo Tavanelli ; Ribeiro, Márcio Garcia (Semina:Ciencias Agrarias, 2019) [Resenha]

  Escherichia coli (E. coli) is a normal inhabitant of the enteric microflora of human and animal. Intestinal and extra-intestinal infections caused by E. coli in mammals are characterized by the presence of diversity of ...

• Silibinin downregulates the NF-κB pathway and NLRP1/NLRP3 inflammasomes in monocytes from pregnant women with preeclampsia 

  Matias, Mariana Leticia ; Gomes, Virginia Juliani ; Romao-Veiga, Mariana ; Ribeiro, Vanessa Rocha ; Nunes, Priscila Rezeck ; Romagnoli, Graziela Gorete ; Peracoli, Jose Carlos ; Peracoli, Maria Terezinha Serrao (Molecules, 2019) [Artigo]

  Preeclampsia (PE) is a human pregnancy-specific syndrome with abnormal activation of cells from the innate immune system. The present study evaluated whether silibinin (SB) treatment of monocytes from preeclamptic women ...

• Differential behavior of non-albicans Candida species in the central nervous system of immunocompetent and immunosuppressed mice 

  Sanches, Marcelo D'Alessandre ; Mimura, Luiza A.N. ; Oliveira, Larissa R.C. ; Ishikawa, Larissa L.W. ; Garces, Hans G. ; Bagagli, Eduardo ; Sartori, Alexandrina ; Kurokawa, Cilmery Suemi ; Fraga-Silva, Thais F.C. (Frontiers in Microbiology, 2019) [Artigo]

  The genus Candida includes commensal fungi that can cause local and systemic infections, frequently involving vital organs as the central nervous system (CNS). Candida spp. occupy the fourth place among infections that ...

• Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus 

  Oliveira, Ilanna Vanessa Pristo de Medeiros; Freire, Débora Alves de Carvalho; Ferreira, Heider Irinaldo Pereira; Moura, Gabriela Hemylin Ferreira; da Rocha, Célio Souza; Calabuig, Cecilia Irene Pérez; Kurissio, Jacqueline Kazue ; Junior, João Pessoa Araújo ; Antunes, João Marcelo Azevedo de Paula (Veterinary and Animal Science, 2018) [Artigo]

  Although reproductive failures (RF) such as abortion, stillbirth and neonatal mortality in cats are still under researched, it is known that many RF are caused by viral agents. This research surveyed the viral agent ...

• A new chemotherapeutic approach using doxorubicin simultaneously with geopropolis favoring monocyte functions 

  Oliveira, Lucas Pires Garcia ; Conte, Fernanda Lopes ; de Oliveira Cardoso, Eliza ; Conti, Bruno José ; Santiago, Karina Basso ; de Assis Golim, Marjorie ; da Silva Feltran, Geórgia ; Zambuzzi, Willian Fernando ; Sforcin, José Maurício (Life Sciences, 2019) [Artigo]

  Aims: Chemotherapy has been widely used to treat cancer although it may affect non-target cells involved in the immune response. This work aimed at elucidating whether the chemotherapeutic agent doxorubicin in combination ...

• The chemical composition and events related to the cytotoxic effects of propolis on osteosarcoma cells: A comparative assessment of Colombian samples 

  Mora, Dolly Patricia Pardo; Santiago, Karina Basso ; Conti, Bruno José ; de Oliveira Cardoso, Eliza ; Conte, Fernanda Lopes ; Oliveira, Lucas Pires Garcia ; de Assis Golim, Marjorie ; Uribe, Jaime Fabian Cruz; Gutiérrez, Rafael María; Buitrago, Mauricio Rey et al. (Phytotherapy Research, 2019) [Artigo]

  Osteosarcoma (OSA) is a type of bone cancer showing an aggressive biological behavior with metastatic progression. Because propolis potential for the development of new antitumoral drugs has been indicated, we evaluated ...

• CD4+CD69+ T cells and CD4+CD25+FoxP3+ Treg cells imbalance in peripheral blood, spleen and peritoneal lavage from pristane-induced systemic lupus erythematosus (SLE) mice 

  Peixoto, Tatiana Vasconcelos; Carrasco, Solange; Botte, Domingos Alexandre Ciccone; Catanozi, Sergio; Parra, Edwin Roger; Lima, Thaís Martins; Ugriumov, Natasha; Soriano, Francisco Garcia; de Mello, Suzana Beatriz Verissímo; Rodrigues, Caio Manzano et al. (Advances in rheumatology (London, England), 2019) [Artigo]

  BACKGROUND: Adaptive immune cells, including CD4+CD69+ and CD4+CD25+FoxP3+ regulatory T (Treg) cells, are important for maintaining immunological tolerance. In human systemic lupus erythematosus (SLE), CD4+CD25+FoxP3+ Treg ...

• Applicability of the SNPforID 52-plex panel for human identification and ancestry evaluation in a Brazilian population sample by next-generation sequencing 

  Valle-Silva, Guilherme do; Souza, Flávia Djenane Nunes de; Marcorin, Letícia; Pereira, Alison Luis Eburneo; Carratto, Thássia Mayra Telles; Debortoli, Guilherme; Oliveira, Maria Luiza Guimarães de; Fracasso, Nádia Carolina de Aguiar; Andrade, Edilene Santos de; Donadi, Eduardo Antônio et al. (Forensic Science International: Genetics, 2019) [Artigo]

  SNP analysis is of paramount importance in forensic genetics. The development of new technologies in next-generation sequencing allowed processing a large number of markers in various samples simultaneously. Although SNPs ...

• Autologous hematopoietic stem cell transplantation for autoimmune diseases: From mechanistic insights to biomarkers 

  Malmegrim, Kelen Cristina Ribeiro; Lima-Júnior, João Rodrigues; Arruda, Lucas Coelho Marlière; De Azevedo, Júlia Teixeira Cottas; De Oliveira, Gislane Lelis Vilela ; Oliveira, Maria Carolina (Frontiers in Immunology, 2018) [Resenha]

  Phase I/II clinical trials of autologous hematopoietic stem cell transplantation (AHSCT) have led to increased safety and efficacy of this therapy for severe and refractory autoimmune diseases (AD). Recent phase III ...

• HLA-G, -E and -F regulatory and coding region variability and haplotypes in the Beninese Toffin population sample 

  Sonon, Paulin; Sadissou, Ibrahim; Tokplonou, Léonidas; M'po, Kuumaaté K.G.; Glitho, Sonya S.C.; Agniwo, Privat; Ibikounlé, Moudachirou; Massaro, Juliana Doblas; Massougbodji, Achille; Moreau, Philippe et al. (Molecular Immunology, 2018) [Artigo]

  HLA-G/E/F genes exhibit immunomodulatory properties and are expressed in placenta. Little attention has been devoted to the study of these genes in sub-Saharan African populations, which are yet the most diverse. To fill ...

• Exercise rescues the immune response fine-tuned impaired by peroxisome proliferator-activated receptors γ deletion in macrophages 

  Silveira, Loreana Sanches ; Batatinha, Helena Angélica Pereira; Castoldi, Angela; Câmara, Niels Olsen Saraiva; Festuccia, Willian T.; Souza, Camila Oliveira; Rosa Neto, José Cesar; Lira, Fábio Santos (Journal of Cellular Physiology, 2019) [Artigo]

  Background: Exercise is a powerful tool for prevention and treatment of many conditions related to the cardiovascular system and also chronic low-grade inflammation. Peroxisome proliferator-activated receptors γ (PPARγ) ...

• Calming Down Mast Cells with Ketotifen: A Potential Strategy for Multiple Sclerosis Therapy? 

  Pinke, Karen Henriette ; Zorzella-Pezavento, Sofia Fernanda Gonçalves ; de Campos Fraga-Silva, Thais Fernanda ; Mimura, Luiza Ayumi Nishiyama ; de Oliveira, Larissa Ragozo Cardoso ; Ishikawa, Larissa Lumi Watanabe ; Fernandes, Ana Angélica Henrique ; Lara, Vanessa Soares; Sartori, Alexandrina (Neurotherapeutics, 2019) [Artigo]

  Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterized by extensive inflammation, demyelination, axonal loss and gliosis. Evidence indicates that mast cells contribute to ...

• Characterization of Escherichia coli obtained from patients undergoing peritoneal dialysis and diagnosed with peritonitis in a Brazilian centre 

  Dias, Regiane C B ; Vieira, Melissa A. ; Moro, Ana C. ; Ribolli, Danilo F M ; Monteiro, Aydir C M ; Camargo, Carlos H.; Tiba-Casas, Monique R.; Soares, Flávia B; Dos Santos, Luis F.; Montelli, Augusto C. et al. (Journal of medical microbiology, 2019) [Artigo]

  Purpose. This study aimed to characterize 27 Escherichia coli isolates obtained from peritoneal dialysis (PD)-related peritonitis that occurred at the University Hospital of Botucatu Medical School, Brazil, between 1997 ...

• Biofilm production under different atmospheres and growth media by Streptococcus agalactiae isolated from milk of cows with subclinical mastitis 

  Bonsaglia, Erika C. R. ; Latosinski, Giulia S. ; Rossi, Rodolfo S. ; Rossi, Bruna F. ; Possebon, Fábio S. ; Pantoja, José Carlos F. ; Fernandes Júnior, Ary ; Rall, Vera L. M. (Archives of Microbiology, 2019) [Artigo]

  Different methods to analyze Streptococcus agalactiae biofilm formation have been investigated, but standardized protocols have not been developed. We compared S. agalactiae biofilm production among different atmospheres ...

• First Microbiological and Molecular Identification of Rhodococcus equi in Feces of Nondiarrheic Cats 

  Lechinski de Paula, Carolina ; Silveira Silva, Rodrigo Otávio; Tavanelli Hernandes, Rodrigo ; de Nardi Júnior, Geraldo; Babboni, Selene Daniela; Trevizan Guerra, Simony ; Paganini Listoni, Fernando José ; Giuffrida, Rogério; Takai, Shinji; Sasaki, Yukako et al. (BioMed research international, 2019) [Artigo]

  Rhodococcus equi is responsible for infections in multiple-host animals. In humans, the prevalence of rhodococcus has increased worldwide and represents an emergent risk. R. equi is a soil-borne opportunistic bacterium ...

• Gliotoxin aggravates experimental autoimmune encephalomyelitis by triggering neuroinflammation 

  Fraga-Silva, Thais Fernanda de Campos ; Mimura, Luiza Ayumi Nishiyama ; Leite, Laysla de Campos Toledo ; Borim, Patrícia Aparecida ; Ishikawa, Larissa Lumi Watanabe ; Venturini, James ; de Arruda, Maria Sueli Parreira ; Sartori, Alexandrina (Toxins, 2019) [Artigo]

  Gliotoxin (GTX) is the major and the most potent mycotoxin that is secreted by Aspergillus fumigatus, which is capable of injuring and killing microglial cells, astrocytes, and oligodendrocytes. During the last years, ...

• First Microbiological and Molecular Identification of Rhodococcus equi in Feces of Nondiarrheic Cats 

  De Paula, Carolina Lechinski ; Silva, Rodrigo Otávio Silveira; Hernandes, Rodrigo Tavanelli ; Júnior, Geraldo De Nardi; Babboni, Selene Daniela; Guerra, Simony Trevizan ; Listoni, Fernando José Paganini ; Giuffrida, Rogério; Takai, Shinji; Sasaki, Yukako et al. (BioMed Research International, 2019) [Artigo]

  Rhodococcus equi is responsible for infections in multiple-host animals. In humans, the prevalence of rhodococcus has increased worldwide and represents an emergent risk. R. equi is a soil-borne opportunistic bacterium ...

• PRP8 Intein in Onygenales: Distribution and Phylogenetic Aspects 

  Garcia Garces, Hans ; Hamae Yamauchi, Danielle ; Theodoro, Raquel Cordeiro; Bagagli, Eduardo (Mycopathologia, 2019) [Artigo]

  Inteins (internal proteins) are mobile genetic elements, inserted in housekeeping proteins, with self-splicing properties. Some of these elements have been recently pointed out as modulators of genetic expression or protein ...

• Downregulation of CD163 in monocytes and its soluble form in the plasma is associated with a pro-inflammatory profile in pregnant women with preeclampsia 

  Nunes, Priscila R. ; Romão-Veiga, Mariana ; Peraçoli, José C. ; Araujo Costa, Roberto A. ; de Oliveira, Leandro G. ; Borges, Vera Therezinha M. ; Peraçoli, Maria Terezinha (Immunologic Research, 2019) [Artigo]

  Preeclampsia (PE) is a pregnancy-specific syndrome characterized by a systemic inflammatory response that polarizes peripheral blood monocytes to the M1 phenotype. The classically activated M1 monocytes comprise immune ...

• Identification and characterization of atypical enteropathogenic and Shiga toxin-producing Escherichia coli isolated from ground beef and poultry breast purchased in Botucatu, Brazil 

  Tanabe, Rodrigo H. S. ; Vieira, Melissa A. ; Mariano, Noelle A. B. ; Dias, Regiane C. B. ; da Silva, Rafael Ventin; Castro, Caroline M. ; dos Santos, Luis F.; Camargo, Carlos H.; Yamatogi, Ricardo S. ; Rall, Vera L. M. et al. (Brazilian Journal of Microbiology, 2019) [Artigo]

  Atypical enteropathogenic (serotypes O4:H16, O8:H25, O68:H2, O105:H7, and OR:H25) and Shigatoxigenic (ONT:H46) Escherichia coli were isolated from samples of ground beef and poultry breast purchased in Botucatu, Brazil. ...

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