Recent Submissions

  • Cylindrospermopsin Disrupts Estrous Cycle and Increases Spermatogenesis in Mice

    de Moraes, Adriana Carvalho Natal; Caires, Fernanda Oliveira; Imperio, Guinever Eustaquio; Nóbrega, Rafael Henrique Autor UNESP; Ortiga-Carvalho, Tania Maria; de Magalhães, Valéria Freitas (Reproductive Sciences, 2022) [Artigo]
    Cylindrospermopsin (CYN) is a water-soluble cyanotoxin that has been linked to several cases of poisoning in the world. In vitro studies have shown that CYN acts as an endocrine disruptor by inhibiting progesterone synthesis ...
  • Toxicological analysis and efficacy of 2-phenylchromone on mycobacteria viability and inflammatory response induced by Mycobacterium bovis

    Moreira, Flora Martinez Figueira; Radai, Joyce Alencar Santos; de Souza, Vanessa Vilamaior; Berno, Claudia Rodrigues; de Araújo, Flavio Henrique Souza; Andrade-Silva, Magaiver; Oliveira, Rodrigo Juliano; Arena, Arielle Cristina Autor UNESP; Henriques, Maria das Graças Müller de Oliveira; Kassuya, Candida Aparecida Leite et al. (Phytomedicine Plus, 2021) [Artigo]
    Background: Studies have reported that compounds similar to flavone present antimicrobial and anti-inflammatory properties; however these effects are poorly described in the context of mycobacterium infection. Purpose: ...
  • Beta-caryophyllene as an antioxidant, anti-inflammatory and re-epithelialization activities in a rat skin wound excision model

    Gushiken, Lucas Fernando Sérgio Autor UNESP; Beserra, Fernando Pereira Autor UNESP; Hussni, Maria Fernanda Autor UNESP; Gonzaga, Murilo Tireli Autor UNESP; Ribeiro, Victor Pena; De Souza, Patrícia Fernanda; Campos, Jacqueline Costa Lima; Massaro, Taís Nader Chrysostomo; Hussni, Carlos Alberto Autor UNESP; Takahira, Regina Kiomi Autor UNESP et al. (Oxidative Medicine and Cellular Longevity, 2022) [Artigo]
    The skin is a critical organ for the maintenance of the integrity and protection of the organism. When a wound occurs, a sequence of healing mechanisms is triggered to reconstruct the wounded area. β-caryophyllene is a ...
  • Mucinous metaplasia in Pten conditional knockout mice and mucin family genes as prognostic markers for prostate cancer

    Santos, Nilton J. Autor UNESP; Ximenes, Pedro Pol Autor UNESP; Constantino, Flávia Bessi Autor UNESP; Carvalho, Hernandes F.; Felisbino, Sérgio Luis Autor UNESP (Life Sciences, 2022) [Artigo]
    Aims: This study evaluated the association of mucinous metaplasia (MM) with tumor cell proliferation, androgen receptor (AR) expression and invasiveness in Pten conditional knockout mice and the prognostic value of MM ...
  • Natural Products as Sources of New Analgesic Drugs

    Arena, Arielle Cristina Autor UNESP; Leite Kassuya, Candida Aparecida; Konkiewitz, Elisabete Castelon; Ziff, Edward Benjamin (Evidence-based Complementary and Alternative Medicine, 2022) [Editorial]
  • Genetic markers indicate that hybrids of Pseudoplatystoma (Siluriformes, Pimelodidae) are reproducing in natural environments in southeastern Brazil

    Freitas-Souza, Diogo Autor UNESP; Nobile, André Batista Autor UNESP; do Prado, Fernanda Dotti Autor UNESP; Serrano, Érica Alves Autor UNESP; Lima, Felipe Pontieri Autor UNESP; Foresti, Fausto Autor UNESP; Porto-Foresti, Fábio Autor UNESP; Oliveira, Claudio Autor UNESP (Biological Invasions, 2022) [Artigo]
    Due to the constant propagule pressure of invasive species, aquaculture is considered to be one of the principal mechanisms for the introduction of non-native fish species into wild habitats in Brazil. The ongoing expansion ...
  • Evaluation of the safety of ethanolic extract from Piper amalago L. (Piperaceae) leaves in vivo: Subacute toxicity and genotoxicity studies

    Stein, Julia Autor UNESP; Jorge, Bárbara Campos Autor UNESP; Casali Reis, Ana Carolina Autor UNESP; Santos Radai, Joyce Alencar; da Silva Moreira, Suyane Autor UNESP; Fraga, Thiago Leite; da Silva Mota, Jonas; Oliveira, Rodrigo Juliano; Kassuya, Cândida Aparecida Leite; Arena, Arielle Cristina Autor UNESP (Regulatory Toxicology and Pharmacology, 2022) [Artigo]
    Piper amalago L. (Piperaceae) is traditionally used due to its anti-inflammatory, analgesic, diuretic, and antiparasitic properties. However, few studies have focused on its adverse effects, compromising its safe use. This ...
  • Shedding light on the impacts of gestational exposure to polystyrene nanoplastics on the reproductive performance of Poecilia reticulata female and on the biochemical response of embryos

    Malafaia, Guilherme Autor UNESP; Nóbrega, Rafael Henrique Autor UNESP; Luz, Thiarlen Marinho da; Araújo, Amanda Pereira da Costa (Journal of Hazardous Materials, 2022) [Artigo]
    Although the toxicity of nanoplastics (NPs) has already been reported in experimental aquatic models, their possible effects on the reproductive performance of viviparous freshwater fish and their consequences for embryos, ...
  • What do environmental advertisers Say and how does the public understand them? Contributions to education for sustainability

    Campos, Natália Aparecida; Malafaia, Guilherme; Doretto, Lucas Benites Autor UNESP; Rosa, Ivana Felipe Autor UNESP; Nóbrega, Rafael Henrique Autor UNESP; Sueli de Lima Rodrigues, Aline (Case Studies in Chemical and Environmental Engineering, 2021) [Artigo]
    Different strategies focused on mitigating, remedying, or preventing the intensification of environmental issues have been adopted by several institutions, organizations, governments, media, among others. One of these ...
  • Prediction of Non-canonical Routes for SARS-CoV-2 Infection in Human Placenta Cells

    Constantino, Flávia Bessi Autor UNESP; Cury, Sarah Santiloni Autor UNESP; Nogueira, Celia Regina Autor UNESP; Carvalho, Robson Francisco Autor UNESP; Justulin, Luis Antonio Autor UNESP (Frontiers in Molecular Biosciences, 2021) [Artigo]
    The SARS-CoV-2 is the causative agent of the COVID-19 pandemic. The data available about COVID-19 during pregnancy have demonstrated placental infection; however, the mechanisms associated with intrauterine transmission ...
  • Multidimensional single-nuclei rna-seq reconstruction of adipose tissue reveals adipocyte plasticity underlying thermogenic response

    Biagi, Carlos Alberto Oliveira de; Cury, Sarah Santiloni Autor UNESP; Alves, Cleidson Pádua; Rabhi, Nabil; Silva, Wilson Araujo; Farmer, Stephen R.; Carvalho, Robson Francisco Autor UNESP; Batista, Miguel Luiz (Cells, 2021) [Artigo]
    Adipose tissue has been classified based on its morphology and function as white, brown, or beige/brite. It plays an essential role as a regulator of systemic metabolism through paracrine and endocrine signals. Recently, ...
  • Drug repositioning based on the reversal of gene expression signatures identifies top2a as a therapeutic target for rectal cancer

    Carvalho, Robson Francisco Autor UNESP; Canto, Luisa Matos Do; Cury, Sarah Santiloni Autor UNESP; Hansen, Torben Frøstrup; Jensen, Lars Henrik; Rogatto, Silvia Regina (Cancers, 2021) [Artigo]
    Rectal cancer is a common disease with high mortality rates and limited therapeutic options. Here we combined the gene expression signatures of rectal cancer patients with the reverse drug-induced gene-expression profiles ...
  • Fish genomics and its impact on fundamental and applied research of vertebrate biology

    Ahmad, Syed Farhan Autor UNESP; Jehangir, Maryam Autor UNESP; Srikulnath, Kornsorn; Martins, Cesar Autor UNESP (Reviews in Fish Biology and Fisheries, 2021) [Resenha]
    The living fishes span a unique and interesting set of animals because of their vast diversity, morphology, ecology, genetics and genomics, and higher importance to biology, economy and culture. During the past decade, the ...
  • Maternal protein restriction changes structural and metabolic gene expression in the skeletal muscle of aging offspring rats

    Valente, Jéssica Silvino Autor UNESP; Perez, Érika Stefani Autor UNESP; Zanella, Bruna Tereza Thomazini Autor UNESP; de Paula, Tassiana Gutierrez Autor UNESP; Dos Santos, Sérgio Alexandre Alcantara Autor UNESP; Duran, Bruno Oliveira da Silva; Carvalho, Robson Francisco Autor UNESP; Justulin, Luis Antonio Autor UNESP; Fantinatti, Bruno Evaristo de Almeida Autor UNESP; Dal-Pai-silva, Maeli Autor UNESP (Histology and Histopathology, 2021) [Artigo]
    Maternal protein restriction affects postnatal skeletal muscle physiology with impacts that last through senility. To investigate the morphological and molecular characteristics of skeletal muscle in aging rats subjected ...
  • Accelerated Diversification Explains the Exceptional Species Richness of Tropical Characoid Fishes

    Melo, Bruno F. Autor UNESP; Sidlauskas, Brian L.; Near, Thomas J.; Roxo, Fabio F. Autor UNESP; Ghezelayagh, Ava; Ochoa, Luz E. Autor UNESP; Stiassny, Melanie L. J.; Arroyave, Jairo; Chang, Jonathan; Faircloth, Brant C. et al. (Systematic Biology, 2022) [Artigo]
    The Neotropics harbor the most species-rich freshwater fish fauna on the planet, but the timing of that exceptional diversification remains unclear. Did the Neotropics accumulate species steadily throughout their long ...
  • Toxicological evaluation of ethanolic extract of leaves from Doliocarpus dentatus in Swiss mice

    Branquinho, Lidiane Schultz; Verdan, Maria Helena; dos Santos, Elisangela; Macorini, Luis Fernando Benitez; Maris, Rafael Souza; Kuraoka-Oliveira, Angela Midori; Bacha, Flávia Barbieri; Cardoso, Claudia Andrea Lima; Arena, Arielle Cristina Autor UNESP; Silva-Filho, Saulo Euclides et al. (Drug and Chemical Toxicology, 2021) [Artigo]
    Doliocarpus dentatus (Dilleniaceae) has been used in folk medicine to treat inflammation and pain; however, studies evaluating its toxicity potential, as well as its effects on anxiety and depression, are scarce. This study ...
  • Exposure to bacteriophages t4 and m13 increases integrin gene expression and impairs migration of human pc-3 prostate cancer cells

    Sanmukh, Swapnil Ganesh Autor UNESP; Santos, Nilton J. Autor UNESP; Barquilha, Caroline Nascimento Autor UNESP; Dos Santos, Sérgio Alexandre Alcantara Autor UNESP; Duran, Bruno Oliveira Silva; Delella, Flávia Karina Autor UNESP; Moroz, Andrei Autor UNESP; Justulin, Luis Antonio Autor UNESP; Carvalho, Hernandes F.; Felisbino, Sérgio Luis Autor UNESP (Antibiotics, 2021) [Artigo]
    The interaction between bacteriophages and integrins has been reported in different cancer cell lines, and efforts have been undertaken to understand these interactions in tumor cells along with their possible role in gene ...
  • Magnetic 3D cell culture: State of the art and current advances

    Caleffi, Juliana Trindade Autor UNESP; Aal, Mirian Carolini Esgoti Autor UNESP; Gallindo, Helena de Oliveira Manacorda Autor UNESP; Caxali, Gabriel Henrique Autor UNESP; Crulhas, Bruno Pereira; Ribeiro, Amanda Oliveira Autor UNESP; Souza, Glauco R.; Delella, Flávia Karina Autor UNESP (Life Sciences, 2021) [Resenha]
    Cell culture is an important tool for the understanding of cell biology and behavior. In vitro cultivation has been increasingly indispensable for biomedical, pharmaceutical, and biotechnology research. Nevertheless, with ...
  • Exposure of pregnant rats to stress and/or sertraline: Side effects on maternal health and neurobehavioral development of male offspring

    Lozano, Ana Flávia Quiarato Autor UNESP; Moura, Mayara Silva Autor UNESP; Tavares, Bruna Marques Autor UNESP; Kempinas, Wilma De Grava Autor UNESP (Life Sciences, 2021) [Artigo]
    Aims: Sertraline (SE) is one of the most prescribed medications for treating gestational depression, anxiety and stress. However, little is known about its effects on nervous-system development in offspring. Therefore, ...
  • MicroRNA roles in regeneration: Multiple lessons from zebrafish

    Ribeiro, Amanda Oliveira Autor UNESP; de Oliveira, Arthur Casulli Autor UNESP; Costa, Juliana Mara Autor UNESP; Nachtigall, Pedro Gabriel Autor UNESP; Herkenhoff, Marcos Edgar Autor UNESP; Campos, Vinicius Farias; Delella, Flávia Karina Autor UNESP; Pinhal, Danillo Autor UNESP (Developmental Dynamics, 2022) [Resenha]
    MicroRNAs (miRNAs) are small noncoding RNAs with pivotal roles in the control of gene expression. By comparing the miRNA profiles of uninjured vs. regenerating tissues and structures, several studies have found that miRNAs ...

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