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dc.contributor.authorFong, Angelina Y.
dc.contributor.authorCorcoran, Andrea E.
dc.contributor.authorZimmer, M. Beth
dc.contributor.authorAndrade, Denis V. [UNESP]
dc.contributor.authorMilsom, William K.
dc.identifier.citationRespiratory Physiology & Neurobiology. Amsterdam: Elsevier B.V., v. 164, n. 3, p. 429-440, 2008.
dc.description.abstractWe examined the effect of age, mass and the presence of the pons on the longevity (length of time spontaneous respiratory-related activity is produced) of brainstem-spinal cord preparations of neonatal rodents (rats and hamsters) and the level of oxygenation in the medulla respiratory network in these preparations. We found the longevity of the preparations from both species decreased with increasing postnatal age. Physical removal of the Pons increased respiratory frequency and the longevity of the preparation. However, tissue oxygenation at the level of the medullary respiratory network was not affected by removal of the Pons or increasing postnatal age (up to postnatal day 4). Taken together, these data suggest that the effect of removing the Pons on respiratory frequency and the longevity of brainstem-spinal cord preparations with increasing postnatal age are primarily due to postnatal development and appear to be unrelated to mass or changes in levels of tissue oxygenation. (C) 2008 Elsevier B.V. All rights reserved.en
dc.description.sponsorshipNatural Sciences and Engineering Research Council of Canada (NSERC)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.publisherElsevier B.V.
dc.relation.ispartofRespiratory Physiology & Neurobiology
dc.sourceWeb of Science
dc.subjectRespiratory rhythmogenesisen
dc.subjectPostnatal developmenten
dc.titleRespiratory rhythm of brainstem-spinal cord preparations: Effects of maturation, age, mass and oxygenationen
dcterms.rightsHolderElsevier B.V.
dc.contributor.institutionUniv British Columbia
dc.contributor.institutionFerris State Univ
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.description.affiliationUniv British Columbia, Dept Zool, Vancouver, BC V6T 1Z4, Canada
dc.description.affiliationFerris State Univ, Dept Biol Sci, Big Rapids, MI USA
dc.description.affiliationUniv Estadual Paulista, Dept Zool, Rio Claro, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Dept Zool, Rio Claro, SP, Brazil
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Rio Claropt[1][4]
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