RSS 1.0Artigos - Biologia - IBILCE
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Structural and physicochemical characteristics of taioba starch in comparison with cassava starch and its potential for ethanol production
; Moretti, Márcia Maria de Souza
; Costa, Mariana Souza ; BordignonJunior, Sidnei Emílio ; ; Boscolo, Mauricio ; Gomes, Eleni ; Franco, Célia Maria Landi ; Silva, Roberto da (Industrial Crops and Products, 2020) [Artigo]
Starch is an important raw material in the fermentation industry for producing ethanol, which can then be used as renewable biofuel or as a basis for food, drink and pharmaceutical uses. Many tropical starch-producing ... -
Methoxychalcones: Effect of methoxyl group on the antifungal, antibac-terial and antiproliferative activities
Marques, Beatriz C.; Santos, Mariana B. ; Anselmo, Daiane B. ; Monteiro, Diego A. ; Gomes, Eleni ; Saiki, Marilia F. C. ; Rahal, Paula ; ; ; Regasini, Luis O. (Medicinal Chemistry, 2020) [Artigo]
Background: Chalcones substituted by methoxyl groups have presented a broad spec-trum of bioactivities, including antifungal, antibacterial and antiproliferative effects. However, a clear and unambiguous investigation about ... -
Association of HMIP1 C-893A polymorphism and disease severity in patients with sickle cell anemia
; ; Belini-Junior, Edis; ; ; ; ; Bonini-Domingos, Claudia R. ; ; (Hematology, Transfusion and Cell Therapy, 2020) [Artigo]
Introduction: Sickle cell anemia (SCA) is a Mendelian disorder with a heterogeneous clinical course. The reasons for this phenotypic diversity are not entirely established, but it is known that high fetal hemoglobin levels ... -
A Collagenolytic Aspartic Protease from Thermomucor indicae-seudaticae Expressed in Escherichia coli and Pichia pastoris
Pereira, Waldir Eduardo Simioni; da Silva, Ronivaldo Rodrigues ; ; ; ; Boscolo, Maurício ; Gomes, Eleni ; da Silva, Roberto (Applied Biochemistry and Biotechnology, 2020) [Artigo]
Proteases are produced by the most diverse microorganisms and have a wide spectrum of applications. However, the use of wild microorganisms, mainly fungi, for enzyme production has some drawbacks. They are subject to ... -
A new synthetic methodology for pyridinic sucrose esters and their antibacterial effects against Gram-positive and Gram-negative strains
Mora Vargas, Jorge Andrés; Ortega, Julieth Orduña ; dos Santos, Maitê Bernardo Correia ; Metzker, Gustavo ; Gomes, Eleni ; Boscolo, Mauricio (Carbohydrate Research, 2020) [Artigo]
Described are the development of a new synthetic method using ultrasonic irradiation and sodium methoxide as catalyst for a series of pyridinic sucrose esters (py-SEs), derived from transesterification of sucrose with ... -
Soaking and ozonolysis pretreatment of sugarcane straw for the production of fermentable sugars
Orduña Ortega, Julieth; Mora Vargas, Jorge Andrés ; Perrone, Olavo Micali ; Metzker, Gustavo ; Gomes, Eleni ; da Silva, Roberto ; Boscolo, Mauricio (Industrial Crops and Products, 2020) [Artigo]
In the present study, sugarcane straw residue (SCS) is used to generate fermentable sugars. Impregnation in different media and ozonolysis were combined for SCS treatment. The best results were obtained for the basic medium ... -
Antiviral activity of curcumin-nanoemulsion associated with photodynamic therapy in vulvar cell lines transducing different variants of HPV-16
Bonfim, Caroline Measso do; Monteleoni, Letícia Figueiredo ; Calmon, Marília de Freitas ; Cândido, Natália Maria ; Provazzi, Paola Jocelan Scarin ; ; ; ; ; et al. (Artificial Cells, Nanomedicine and Biotechnology, 2020) [Artigo]
Vulvar intraepithelial neoplasia (VIN) is associated with human papillomavirus (HPV) infection. Curcumin is a natural bioactive compound with antineoplastic properties. The use of nanoparticles containing curcumin could ... -
Relationship of polymorphism rs3800231 in FOXO3 gene and clinical severity with oxidative stress markers in sickle cell disease
Bernardo, Victoria Simões; Torres, Flaviene Felix ; Chaves, Nayara Alves ; ; da Silva, Danilo Grünig Humberto ; Bonini-Domingos, Claudia Regina (Meta Gene, 2020) [Artigo]
Sickle cell disease (SCD) is a hereditary disease characterized by a clinical course highly variable that is significantly affected by several modifying factors, whose majority still poorly understood. Due to the importance ... -
β-Glucosidase production by Trichoderma reesei and Thermoascus aurantiacus by solid state cultivation and application of enzymatic cocktail for saccharification of sugarcane bagasse
Frassatto, Priscila Aparecida Casciatori; ; Thoméo, João Cláudio ; Gomes, Eleni ; Boscolo, Maurício ; da Silva, Roberto (Biomass Conversion and Biorefinery, 2020) [Artigo]
For degradation of sugarcane bagasse (SCB), several enzymes are needed but β-glucosidase is rate limiting in cellulose hydrolysis. Since different microorganisms synthetize characteristic pool of enzymes, mixing extracts ... -
Perinatal exposure to bisphenol A impacts in the mammary gland morphology of adult Mongolian gerbils
Leonel, Ellen Cristina Rivas; ; Bedolo, Carolina Marques Baraldi ; Guerra, Luiz Henrique Alves ; Vilamaior, Patrícia Simone Leite ; Calmon, Marilia Freitas ; Rahal, Paula ; ; Taboga, Sebastião Roberto (Experimental and Molecular Pathology, 2020) [Artigo]
The endocrine disruptive effects caused by bisphenol A (BPA) are well known. Despite this, to date, evaluation of its long term effects is limited, meaning that there is still much to be unveiled in terms of alterations ... -
Stepped vitrification technique for human ovarian tissue cryopreservation
Leonel, Ellen Cristina Rivas; ; ; ; Taboga, Sebastião Roberto ; ; ; ; ; (Scientific Reports, 2019) [Artigo]
The advantage of stepped vitrification (SV) is avoiding ice crystal nucleation, while decreasing the toxic effects of high cryoprotectant concentrations. We aimed to test this method for human ovarian tissue cryopreservation. ... -
Impact of perinatal bisphenol A and 17β estradiol exposure: Comparing hormone receptor response
Leonel, Ellen Cristina Rivas; ; Guerra, Luiz Henrique Alves ; Bedolo, Carolina Marques ; Vilamaior, Patrícia Simone Leite ; Calmon, Marilia Freitas ; Rahal, Paula ; ; Taboga, Sebastião Roberto (Ecotoxicology and Environmental Safety, 2020) [Artigo]
Hormonal regulation controls mammary gland (MG) development. Therefore some hormone-related factors can disrupt the early phases of MGs development, making the gland more susceptible to long term modifications in its ... -
The improvement of grape juice quality using Thermomucor Indicae-Seudaticae pectinase
de Carvalho Tavares, Iasnaia Maria; Umsza-Guez, Marcelo Andrés ; Martin, Natália ; ; Boscolo, Maurício ; Gomes, Eleni ; Da-Silva, Roberto ; Lago-Vanzela, Ellen Silva (Journal of Food Science and Technology, 2020) [Artigo]
The effect of pectinolytic enzyme preparation (PEP) produced by the fungus Thermomucor indicae-seudaticae-N31 (PEP-N31) on total phenolic content, concentrations of methanol and color of grape juice was studied. Positive ... -
Prospecting for l-arabinose/d-xylose symporters from Pichia guilliermondii and Aureobasidium leucospermi
da Silva, Ronivaldo Rodrigues; ; ; Boscolo, Mauricio ; da Silva, Roberto ; Gomes, Eleni (Brazilian Journal of Microbiology, 2020) [Artigo]
With the strong trend toward sustainable technologies, such as the gradual substitution of fossil fuel consumption, improvement in the utilization of sugars from lignocellulosic biomass appears to be an alternative for ... -
Do mineral and corn oil serve as potential endocrine disruptors in the gerbil prostate?
Guerra, Luiz Henrique Alves; ; ; Taboga, Sebastião Roberto ; Vilamaior, Patricia Simone Leite (Reproductive Toxicology, 2019) [Artigo]
Vegetable oils are frequently used as a vehicle in the administration of lipophilic drugs in animal tests. However, the composition of these oils may interfere with the results. One alternative to reduce this potential ... -
Saccharification of pretreated sugarcane bagasse using enzymes solution from Pycnoporus sanguineus MCA 16 and cellulosic ethanol production
Pereira Scarpa, Josiani de Cassia; Paganini Marques, Natália ; Alves Monteiro, Diego ; Martins, Gisele Marta ; Paula, Ariela Veloso de ; Boscolo, Maurício ; da Silva, Roberto ; Gomes, Eleni ; Alonso Bocchini, Daniela (Industrial Crops and Products, 2019) [Artigo]
Pycnoporus sanguineus MCA 16 was cultivated by solid state fermentation on lignocellulosic residues, at 40 °C. The highest endoglucanase, exoglucanase, β-glucosidase, xylanase, β-xylosidase and laccase activities (200, ... -
Wide diversity of fungal species found in wellwater for human consumption: An analytical cross-sectional study
Arroyo, Máira Gazzola; ; ; ; ; ; ; ; ; (Sao Paulo Medical Journal, 2019) [Artigo]
BACKGROUND: Fungi are ubiquitous in the environment. They are able to grow in water and many of them may be opportunistic pathogens. OBJECTIVE: The aims were to identify fungi in registered wells (RWs) and nonregistered ... -
First isolation and genotyping of Toxoplasma gondii in a free-living giant anteater (Myrmecophaga tridactyla) revealed a unique non-archetypal genotype
; Ferrari, Vinícius Matheus; ; ; ; ; ; ; ; et al. (Acta Tropica, 2020) [Artigo]
The protozoan parasite Toxoplasma gondii can infect virtually all warm-blooded animals worldwide but little is known of its infection in the endangered giant anteaters (Myrmecophaga tridactyla). The present study found ... -
Toll-like receptor 9 polymorphisms and Helicobacter pylori influence gene expression and risk of gastric carcinogenesis in the Brazilian population
; ; ; ; Rossi, Ana Flávia Teixeira; Silva, Ana Elizabete ; (World Journal of Gastrointestinal Oncology, 2019) [Artigo]
BACKGROUND Toll-like receptors (TLRs) are the first line of host defense, and are involved in Helicobacter pylori (H. pylori) recognition and activation of both inflammatory and carcinogenic processes. The presence of ... -
Global gene expression profile in canine mammary carcinomas
Varallo, G. R.; ; ; ; (Veterinary Journal, 2019) [Artigo]
Mammary gland tumors are a heterogeneous group of neoplastic diseases. Genetic studies make it possible to determine genetic profiles and identify new molecular markers. The aim of the study was to evaluate the gene ...