RSS 1.0Artigos - Biologia - IBILCE
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Application of a recombinant GH10 endoxylanase from Thermoascus aurantiacus for xylooligosaccharide production from sugarcane bagasse and probiotic bacterial growth
Nascimento, Carlos Eduardo de Oliveira
; Simões, Lorena Caixeta de Oliveira ; Pereira, Josiani de Cassia ; da Silva, Ronivaldo Rodrigues ; ; de Almeida, Gabriel Cimonetti ; Penna, Ana Lucia Barretto ; Boscolo, Maurício ; Gomes, Eleni ; da Silva, Roberto (Journal of Biotechnology, 2022) [Artigo]
Xylooligosaccharides (XOs) are a promising class of prebiotics capable of selectively stimulating the growth of the beneficial intestinal microbiota against intestinal pathogens. They can be obtained from xylan present in ... -
Transposable element expression and regulation profile in gonads of interspecific hybrids of drosophila arizonae and drosophila mojavensis wrigleyi
Banho, Cecília Artico; Oliveira, Daniel Siqueira ; ; ; ; Carareto, Claudia Marcia Aparecida (Cells, 2021) [Artigo]
Interspecific hybridization may lead to sterility and/or inviability through differential expression of genes and transposable elements (TEs). In Drosophila, studies have reported massive TE mobilization in hybrids from ... -
Gestational and lactational xenoestrogen exposure disrupts morphology and inflammatory aspects in mammary gland of gerbil mothers during involution
Ruiz, Thalles Fernando Rocha; Leonel, Ellen Cristina Rivas ; Colleta, Simone Jacovaci ; Bedolo, Carolina Marques ; Pegorin de Campos, Silvana Gisele ; Taboga, Sebastião Roberto (Environmental Toxicology and Pharmacology, 2022) [Artigo]
In the mammary gland (MG), the developmental window for gestational/lactational differentiation and growth is highly vulnerable to hormonal disruption. Here we describe that the MG involution process in female gerbil mothers ... -
Protective effects of piperlongumin in the prevention of inflammatory damage caused by pulmonary exposure to benzopyrene carcinogen
Ashino, Tissiane Eid Barbosa; ; ; Possebon, Lucas ; de Souza Costa, Sara ; ; Souza, Helena Ribeiro ; ; Oliani, Sonia Maria ; Girol, Ana Paula (International Immunopharmacology, 2021) [Artigo]
Benzopyrene is one of the main polycyclic aromatic hydrocarbons with carcinogenic capacity. Research has shown that anti-inflammatory drugs can reduce the incidence of lung cancer. In this scenario, we highlight piperlongumin ... -
Mammary carcinoma in aged gerbil mothers after endocrine disruption in pregnancy and lactation
Ruiz, Thalles Fernando Rocha; Colleta, Simone J. ; ; Taboga, Sebastião Roberto (Endocrine-related cancer, 2021) [Artigo]
Compounds that trigger breast cancer onset and establishment are of great interest in biological research. Endocrine disruptors are relevant because they initiate carcinogenesis by changing endocrine pathways. Bisphenol A ... -
Functional properties and potential application of ethanol tolerant β-glucosidases from Pichia ofunaensis and Trichosporon multisporum yeasts
Vaz, Jaqueline Elaine; Rabelo, Lacan ; Zaiter, Mohammed Anas ; Pereira, Waldir Eduardo Simioni ; Metzker, Gustavo ; Boscolo, Maurício ; da Silva, Roberto ; Gomes, Eleni ; da Silva, Ronivaldo Rodrigues (3 Biotech, 2021) [Artigo]
β-Glucosidases have been extensively investigated to integrate the enzyme complex for cellulose fiber saccharification and for improving the aroma of wine. To produce these enzymes, greater attention has been given to ... -
Hormone receptor expression in aging mammary tissue and carcinoma from a rodent model after xenoestrogen disruption
Ruiz, Thalles Fernando Rocha; Colleta, Simone Jacovaci ; ; Vilamaior, Patrícia Simone Leite ; ; Taboga, Sebastião Roberto (Life Sciences, 2021) [Artigo]
Aims: Hormone receptors are the main markers applied for prognosis of breast cancer subtypes. Among modulators, exogenous chemical agents known as endocrine disruptors interact with certain receptors, triggering molecular ... -
Annexin A1 Mimetic Peptide Ac2-26 Modulates the Function of Murine Colonic and Human Mast Cells
; Prates, Janesly; ; ; Oliani, Sonia Maria (Frontiers in Immunology, 2021) [Artigo]
Mast cells (MCs) are main effector cells in allergic inflammation and after activation, they release stored (histamine, heparin, proteases) and newly synthesized (lipid mediators and cytokines) substances. In the ... -
Recent advances in SARS-CoV-2 Spike protein and RBD mutations comparison between new variants Alpha (B.1.1.7, United Kingdom), Beta (B.1.351, South Africa), Gamma (P.1, Brazil) and Delta (B.1.617.2, India)
Sanches, Paulo R.S.; ; ; Bittar, Cíntia ; Freitas Calmon, Marilia ; Rahal, Paula ; Cilli, Eduardo M. (Journal of Virus Eradication, 2021) [Artigo]
New variants of SARS-CoV-2 Alpha (B.1.1.7); Beta (B.1.351) Gamma (P.1) and Delta (B.1.617.2) quickly spread in the UK, South Africa, Brazil and India, respectively. To address whether mutations in SARS-CoV-2 RBD spike ... -
Curcumin-cinnamaldehyde hybrids as antiproliferative agents against women’s cancer cells
Anselmo, Daiane B.; Polaquini, Carlos R. ; Marques, Beatriz C. ; Ayusso, Gabriela M. ; Assis, Letícia R. ; Torrezan, Guilherme S. ; Rahal, Paula ; ; Calmon, Marília F. ; et al. (Medicinal Chemistry Research, 2021) [Artigo]
Curcumin and cinnamaldehyde are natural products whose antineoplastic activity has been well explored in biological evaluations. However, their poor chemical stability under physiological conditions has been an obstacle ... -
Inflammatory repercussions in female steroid responsive glands after perinatal exposure to bisphenol A and 17-β estradiol
Leonel, Ellen Cristina Rivas; Ruiz, Thalles Fernando Rocha ; Bedolo, Carolina Marques ; Campos, Silvana Gisele Pegorin ; Taboga, Sebastião Roberto (Cell Biology International, 2021) [Artigo]
The mammary gland (MG) and female prostate are plastic reproductive organs which are highly responsive to hormones. Thus, endocrine disruptors, such as bisphenol A (BPA) and exogenous estrogens, negatively affect glandular ... -
Case study of two post vaccination SARS-CoV-2 infections with P1 variants in coronavac vaccinees in Brazil
; ; ; ; ; Ullmann, Leila S.; Possebon, Fabio S. ; ; ; Araújo Junior, João P. et al. (Viruses, 2021) [Artigo]
The rapid development of efficacious and safe vaccines against coronavirus disease 2019 (COVID-19) has been instrumental in mitigating the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ... -
Oxidative stress and sickle cell disease
Da Silva, Danilo Grünig Humberto; Junior, Edis Belini ; Bonini-Domingos, Claudia Regina ; De Almeida, Eduardo Alves (Reactive Oxygen Species in Biology and Human Health, 2017) [Capítulo de livro]
Sickle cell disease (SCD) embraces a group of genetic hemolytic disorders associated with high morbidity and mortality. SCD is characterized by a complex pathophysiology initiated by hemoglobin S (HbS) polymerization that ... -
Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
Rossi, Livia Maria Gonçalves; Rahal, Paula (American Journal of Infectious Diseases, 2014) [Artigo]
Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, ... -
Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
Rossi, Livia Maria Gonçalves; Rahal, Paula (American Journal of Infectious Diseases, 2014) [Artigo]
Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, ... -
Acid phosphatase in blood smears of Phrynops geoffroanus (Testudines: Chelidae)
da Silva, Maria Isabel Afonso; Oliveira, Maria Tercília Vilela de Azeredo ; Bonini-Domingos, Claudia Regina (Revista Brasileira de Hematologia e Hemoterapia, 2011) [Artigo]
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As hemoglobinopatias e a diversidade genética da população brasileira
Bonini-Domingos, Claudia R. (Revista Brasileira de Hematologia e Hemoterapia, 2009) [Editorial]
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Plasmodium vivax circumsporozoite variants and Duffy blood group genotypes in the Brazilian Amazon region
Storti-Melo, Luciane M.; de Souza-Neiras, Wanessa C. ; Cassiano, Gustavo C. ; ; ; Bonini-Domingos, Cláudia R. ; ; ; de Mattos, Luiz C. ; et al. (Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009) [Artigo]
The circumsporozoite protein (CSP) of the Plasmodium vivax infective sporozoite is considered to be a major target for the development of recombinant malaria vaccines. The Duffy blood group molecule acts as the red blood ... -
Saint Louis encephalitis virus, Brazil [5]
; ; ; ; ; Rahal, Paula; ; ; ; et al. (Emerging Infectious Diseases, 2007) [Carta]
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Female Prostate Development: Morphological Analysis of the Budding Dynamic
(Microscopy and Microanalysis, 2022) [Artigo]The presence of the prostate in female mammals has long been known. However, pieces of information related to its development are still lacking. The aim of this study was to explore the budding dynamic during the initial ...