Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of action

Nenhuma Miniatura disponível

Data

2009-08-01

Autores

Dos Santos, Lucilene D.
Dias, Nathalia B.
Pinto, José Robert O.A.S.
Palma, Mario S. [UNESP]

Título da Revista

ISSN da Revista

Título de Volume

Editor

Resumo

Loxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage to the toxin structures. © 2009 Bentham Science Publishers Ltd.

Descrição

Palavras-chave

Mass spectrometry, Mechanism of action, MudPIT, Proteomic analysis, Spider venom

Como citar

Protein and Peptide Letters, v. 16, n. 8, p. 933-943, 2009.