RSS 1.0Departamento de Ciências Biológicas
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Fitoterápicos para o tratamento de doenças crônicas
Vilegas, Wagner
(2019) [Plano de gestão de dados]
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Integrating multiple lines of evidence of sediment quality in a tropical bay (Guanabara Bay, Brazil)
de Campos, Bruno Galvão; Moreira, Lucas Buruaem ; Pauly, Guacira de Figueiredo Eufrasio ; Cruz, Ana Carolina Feitosa ; ; ; ; ; Abessa, Denis Moledo de Souza (Marine Pollution Bulletin, 2019) [Artigo]
The present study evaluated the ecological risk of metal contamination in sediments of Guanabara Bay (GB) by combining multiple lines of evidence (LOEs). Chemical analysis and a set of whole-sediment toxicity assays were ... -
Can the gastric healing effect of Eugenia punicifolia be the same in male and female rats?
Périco, Larissa Lucena; Rodrigues, Vinícius Peixoto ; Ohara, Rie ; Nunes, Vânia Vasti Alfieri ; da Rocha, Lúcia Regina Machado ; Vilegas, Wagner ; dos Santos, Catarina ; Hiruma-Lima, Clélia Akiko (Journal of Ethnopharmacology, 2019) [Artigo]
Ethnopharmacological relevance: Eugenia punicifolia (Kunth) DC. (Myrtaceae), an Amazonian medicinal plant known as “pedra-ume-caá,” is popularly used as a natural remedy for inflammation, wounds, infections, diabetes, ... -
Byrsonima intermedia A. Juss partitions promote gastroprotection against peptic ulcers and improve healing through antioxidant and anti-inflammatory activities
de Cássia dos Santos, Raquel; Bonamin, Flavia ; Périco, Larissa Lucena ; Rodrigues, Vinícius Peixoto ; Zanatta, Ana Caroline ; ; ; dos Santos Ramos, Matheus Aparecido ; Bonifácio, Bruna Vidal ; Bauab, Taís Maria et al. (Biomedicine and Pharmacotherapy, 2019) [Artigo]
Byrsonima intermedia is a species of bush popularly used to treat gastrointestinal disorders, such as gastric ulcers, gastritis, and diarrhea. Previous studies have revealed that the methanolic crude extract of B. intermedia ... -
Evaluation of the chemopreventive activity of grape skin extract using medium-term oral carcinogenesis assay induced by 4-nitroquinoline 1-oxide
; ; ; Silva, Marcelo Jose Dias; Vilegas, Wagner ; ; ; ; (Anticancer Research, 2019) [Artigo]
Background/Aim: The aim of this study was to evaluate the chemoprotective potential of grape skin extract following rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide (4NQO). Materials and Methods: Male Wistar ... -
Assessing the ecological effects of contaminants in estuaries in Brazil: Gaps and future directions
; Abessa, Denis Moledo de Souza; (Ecotoxicology in Latin America, 2017) [Capítulo de livro]
This chapter reviews published papers from the last 15 years that estimate the effects of contamination in Brazilian estuaries. The goals were to identify (i) the main classes of contaminants studied in estuarine systems ... -
Semisynthetic Derivative of Artemisia annua-Loaded Transdermal Bioadhesive for the Treatment of Uncomplicated Malaria Caused by Plasmodium falciparum in Children
; ; ; Fonseca-Santos, Bruno; ; ; ; Vilegas, Wagner ; Chorilli, Marlus ; et al. (Journal of Pharmaceutical Sciences, 2019) [Artigo]
According to the most recent World Health Organization statistics, malaria infected approximately 219 million people in 2017, with an estimate of 435,000 deaths (World Health Organization, 2018). Communities isolated from ... -
Chemical constituents and allelopathic activity of Machaerium eriocarpum Benth.
; ; Zanatta, Ana C.; ; Franco, Danilo Miralha ; Hiruma-Lima, Clélia Akiko ; Vilegas, Wagner ; de Almeida, Luiz Fernando Rolim ; (Natural Product Research, 2018) [Artigo]
The analysis by HPLC-PDA of the hydroalcoholic extract of the leaves of M. eriocarpum together with the injection of the fractions containing the already identified metabolites allowed the detection of at least 5 flavonoids, ... -
Thimet Oligopeptidase (EC 3.4.24.15) Key Functions Suggested by Knockout Mice Phenotype Characterization
(Biomolecules, 2019) [Artigo]Thimet oligopeptidase (THOP1) is thought to be involved in neuropeptide metabolism, antigen presentation, neurodegeneration, and cancer. Herein, the generation of THOP1 C57BL/6 knockout mice (THOP1-/-) is described showing ... -
Testing the dear enemy relationship in fiddler crabs: Is there a difference between fighting conspecific and heterospecific opponents?
Fogo, Bruno R.; Sanches, Fábio H.C. ; Costa, Tânia M. (Behavioural Processes, 2019) [Artigo]
Reduction of aggressiveness toward familiar neighbors, when compared to aggressiveness toward unfamiliar strangers, can decrease the costs of territory defense. This phenomenon is known as the “dear enemy effect”. Individuals ... -
Enteric nervous system analyses: New biomarkers for environmental quality assessment
Pustiglione Marinsek, Gabriela; Moledo de Souza Abessa, Denis ; Gusso-Choueri, Paloma Kachel ; ; Nascimento Gonçalves, Alexandre Rodrigo ; D'angelo Barroso, Beatriz Vivian ; ; ; Galvão de Campos, Bruno ; de Britto Mari, Renata (Marine Pollution Bulletin, 2018) [Artigo]
The gastrointestinal tract (GIT) of fish is a target of contaminants since it can absorb these substances. We evaluated the morphophysiological alterations in the GIT of Sphoeroides testudineus collected in two estuaries ... -
Roughness and its effects on flexural strength of dental yttria-stabilized zirconia ceramics
; ; ; ; Simba, Bruno Galvão; (Materials Science and Engineering A, 2019) [Artigo]
This study evaluated the effect of the surface roughness parameters on the flexural strength of Yttria-partially stabilized zirconia, Y-TZP ceramics: ZrO2 (3 mol%) or ZrO2 (5 mol%), as function of different surface finishing ... -
Impacts of dredging on biomarkers responses of caged bivalves in a semi-arid region (Ceará State, NE Brazil)
Moreira, Lucas B.; ; ; ; ; Abessa, Denis M.S. (Marine Environmental Research, 2019) [Artigo]
In this study, the performance of two native bivalves in responding to sediment resuspension was investigated during dredging operations of a semi-arid bay (Mucuripe, NE Brazil). The clam Anomalocardia flexuosa and the ... -
Common snook juveniles, Centropomus undecimalis, as biomonitor organisms to evaluate cytogenotoxicity effects of surface estuarine water from Southern Brazil
; ; ; Nobre, Caio Rodrigues; Maranho, Luciane Alves ; ; Abessa, Denis Moledo de Souza ; ; (Marine Pollution Bulletin, 2019) [Artigo]
Centropomus undecimalis fish inhabit the highly contaminated Santos-São Vicente Estuarine System (SESS) and could be a good biomonitor of contaminants. This study aimed to investigate the cytogenotoxic potential of superficial ... -
LC–ESI–IT-MS/MS and MALDI-TOF Approach: Identification of Natural Polymers from Rhizophora mangle Barks and Determination of Their Analgesic and Anti-inflammatory Properties
de Souza Mesquita, Leonardo Mendes; Rodrigues, Caroline Fabri Bittencourt ; da Rocha, Cláudia Quintino ; Bianchim, Mayara Silveira ; ; ; Gaeta, Henrique Hessel ; Belchor, Mariana Novo ; Toyama, Marcos Hikari ; Vilegas, Wagner (Natural Products and Bioprospecting, 2019) [Artigo]
Abstract: We recognize the chemical composition of the acetonic extract of Rhizophora mangle barks (AERM) using mass spectrometry analysis [liquid chromatography (LC)–ESI–IT-MS/MS and matrix-assisted laser desorption/ion ... -
High CO2 favors ionic homeostasis, photoprotection, and lower photorespiration in salt-stressed cashew plants
; ; ; Lima Neto, Milton Costa; ; ; (Acta Physiologiae Plantarum, 2019) [Artigo]
The aim of this study was to evaluate the effects of elevated CO2 concentration on acclimation mechanisms related to gas exchange, photochemical activity, photorespiration, and oxidative protection in cashew plants exposed ... -
University extension and informal education: Useful tools for bottom-up ocean and coastal literacy of primary school children in Brazil
Stefanelli-Silva, Gabriel; Pardo, Juan C.F. ; ; Costa, Tânia M. (Frontiers in Marine Science, 2019) [Artigo]
While increasing awareness about ocean-related topics is a matter of urgent necessity, ocean and coastal-literate schoolchildren are uncommon in Brazil, even in coastal cities. In the present study, we report the activities ... -
Redescription of the advertisement call of Brachycephalus tridactylus (Anura: Brachycephalidae)
Bornschein, Marcos R.; Rollo, Mario M. ; ; ; (Phyllomedusa, 2019) [Artigo]
Miniaturized frogs of the genus Brachycephalus have restricted geographical distributions throughout the Atlantic Forest. Ecological data for most species are scarce and advertisement calls have been described for only 12 ... -
Relative growth, sexual maturity and handedness in the ghost shrimp callichirus major (Decapoda: Callianassidae) from the southwestern atlantic
Rio, Juliana Priscila Piva; Hernáez, Patricio ; Pinheiro, Marcelo Antonio Amaro (Scientia Marina, 2019) [Artigo]
Summary: Biometric studies provide valuable information about changes associated with the growth and sexual maturity of living organisms. We analysed sexual dimorphism, allometric growth, sexual maturity and handedness in ... -
The effectiveness of a protection law in favor of conservation of an marine resource: The example of the ghost shrimp Callichirus major (Decapoda, Callianassidae) of the coast of Brazil
Hernáez, Patricio; Hereman, Michael J. ; Pimenta, Camila E. R. ; Rio, Juliana P. P. ; João, Marcio C. A. ; Pinheiro, Marcelo A. A. (Iheringia - Serie Zoologia, 2019) [Artigo]
Studies on mortality due to fishing based on isolating the effect caused by catches are scarce. The present study analyzed this aspect using the ghost shrimp Callichirus major (Say, 1818) as a biological model, which is ...