RSS 1.0Artigos - Bioquímica e Tecnologia - IQ
Browse by
Recent Submissions
-
Magnetic Resonance Spectroscopy as a Non-invasive Method to Quantify Muscle Carnosine in Humans: a Comprehensive Validity Assessment
; ; ; ; Cilli, Eduardo Maffud
; ; ; ; (Scientific Reports, 2020) [Artigo]
Carnosine is a dipeptide abundantly found in human skeletal muscle, cardiac muscle and neuronal cells having numerous properties that confers performance enhancing effects, as well as a wide-range of potential therapeutic ... -
Linear peptide analogues from Jatropha's orbitides promote migration of human neonatal foreskin fibroblasts in vitro and collagen deposition
Ramalho, Suelem D.; Pinto, Meri Emili F. ; ; Sanches, Paulo R. S. ; ; Cilli, Eduardo M. ; ; Bolzani, Vanderlan S. (Journal of the Brazilian Chemical Society, 2019) [Artigo]
Orbitides are a class of small naturally occurring cyclic peptides with structural and functional diversities. Their chemical properties make this class feasible to be obtained by solid phase peptide synthesis (SPPS). ... -
Serological point-of-care and label-free capacitive diagnosis of dengue virus infection
Cecchetto, Juliana; Santos, Adriano ; Mondini, Adriano ; Cilli, Eduardo M. ; Bueno, Paulo R. (Biosensors and Bioelectronics, 2020) [Artigo]
Dengue non-structural protein 1 (NS1 DENV) is considered a biomarker for dengue fever in an early stage. A sensitive and rapid assay for distinguishing positive from negative dengue infection samples is imperative for ... -
Enhancing the Biocatalytic Activity of l -Asparaginase Using Aqueous Solutions of Cholinium-Based Ionic Liquids
Magri, Agnes; Pecorari, Thainá ; ; Cilli, Eduardo M. ; ; Pereira, Jorge F. B. (ACS Sustainable Chemistry and Engineering, 2019) [Artigo]
l-Asparaginase (ASNase) is a high value enzyme for the pharmaceutical and food industries. Although ionic liquids (ILs) have been recognized as promising solvents or additives for biocatalysis, there are very few studies ... -
Bacteriocin enterocin CRL35 is a modular peptide that induces non-bilayer states in bacterial model membranes
; ; Cilli, Eduardo; ; (Biochimica et Biophysica Acta - Biomembranes, 2020) [Artigo]
The mechanism of action of the anti-Listeria peptide enterocin CRL35 was studied with biophysical tools by using lipid mixtures that mimicked Gram-positive plasma membranes. Langmuir monolayers and infrared spectroscopy ... -
Evidence of ferroelectric behaviour in CaCu3Ti4O12 thin films deposited by RF-sputtering
Foschini, Cesar R.; Hangai, Bruno ; Ortega, Pedro Paulo ; Longo, Elson ; Cilense, Mário ; Simões, Alexandre Z. (Processing and Application of Ceramics, 2019) [Artigo]
The origin of abnormal ferroelectric and unusual piezoelectricity in the polycrystalline CaCu3Ti4O12 (CCTO) thin films deposited by RF-sputtering on Pt/Ti/SiO2/Si (100) substrates was explored. The CCTO thin films, deposited ... -
Evaluation of 4-tert-Butyl-Benzhydrylamine Resin (BUBHAR) as an Alternative Solid Support for Peptide Synthesis
(International Journal of Polymer Science, 2020) [Artigo]Following preliminary reports that introduced 4-Tert-butylbenzhydrylamine resin (BUBHAR) as a novel polymer for use in solid-phase peptide chemistry (SPPS), some physical-chemical properties of its structure, certainly ... -
Gentamicin encapsulated within a biopolymer for the treatment of Staphylococcus aureus and Escherichia coli infected skin ulcers
Gemeinder, José Lúcio Pádua; Barros, Natan Roberto de ; Pegorin, Giovana Sant’Ana ; Singulani, Junya de Lacorte ; Borges, Felipe Azevedo ; ; Giannini, Maria José Soares Mendes ; Almeida, Ana Marisa Fusco ; ; Herculano, Rondinelli Donizetti (Journal of Biomaterials Science, Polymer Edition, 2020) [Artigo]
Skin wound infection requires carefully long-term treatment with an immense financial burden to healthcare systems worldwide. Various strategies such as drug delivery systems using polymer matrix from natural source have ... -
GSVA score reveals molecular signatures from transcriptomes for biomaterials comparison
Ferreira, Marcel R.; Santos, Gerson A. ; ; ; Zambuzzi, Willian F. (Journal of Biomedical Materials Research - Part A, 2020) [Artigo]
Two in silico methodologies were implemented to reveal the molecular signatures of inorganic hydroxyapatite and β-TCP materials from a transcriptome database to compare biomaterials. To test this new methodology, we choose ... -
Free and Substrate-Immobilised Lipases from Fusarium verticillioides P24 as a Biocatalyst for Hydrolysis and Transesterification Reactions
Borges, Janaina Pires; Quilles Junior, José Carlos ; Ohe, Thiago Hideyuki Kobe ; Ferrarezi, Ana Lucia ; Nunes, Christiane da Costa Carreira ; Boscolo, Mauricio ; Gomes, Eleni ; Bocchini, Daniela Alonso ; da Silva, Roberto (Applied Biochemistry and Biotechnology, 2020) [Artigo]
Fungal enzymes are widely used in technological processes and have some interesting features to be applied in a variety of biosynthetic courses. Here, free and substrate-immobilised lipases from Fusarium verticillioides ... -
Immunogenicity of HLA-DR1 and HLA-A2 peptides derived from Leishmania major Gp63 in golden hamsters
; ; ; ; ; ; ; Marchetto, Reinaldo; ; (Parasite Immunology, 2020) [Artigo]
Aims: This study aimed to evaluate the toxicity and humoral and cellular immune response of three heterologous vaccines against Leishmania infantum, yet containing synthetic peptides from Leishmania major in the experimental ... -
Enhanced bio-recovery of aluminum from low-grade bauxite using adapted fungal strains
Shah, Syed Sikandar; ; Sponchiado, Sandra Regina Pombeiro ; Bevilaqua, Denise (Brazilian Journal of Microbiology, 2020) [Artigo]
Filamentous fungi have been proved to have a pronounced capability to recover metals from mineral ores. However, the metal recovery yield is reduced due to toxic effects triggered by various heavy metals present in the ... -
Bio- and nanotechnology as the key for clinical application of salivary peptide histatin: A necessary advance
Zambom, Carolina Reis; da Fonseca, Fauller Henrique ; Garrido, Saulo Santesso (Microorganisms, 2020) [Resenha]
Candida albicans is a common microorganism of human’s microbiota and can be easily found in both respiratory and gastrointestinal tracts as well as in the genitourinary tract. Approximately 30% of people will be infected ... -
Ethyl esters production catalyzed by immobilized lipases is influenced by n-hexane and ter-amyl alcohol as organic solvents
Borges, Janaina Pires; Quilles Junior, José Carlos ; ; Fernandez-Lorente, Glória ; Boscolo, Mauricio ; Gomes, Eleni ; da Silva, Roberto ; Bocchini, Daniela Alonso ; (Bioprocess and Biosystems Engineering, 2020) [Artigo]
Lipase stability in organic solvent is crucial for its application in many biotechnological processes as biocatalyst. One way to improve lipase’s activity and stability in unusual reaction medium is its immobilization on ... -
Gene expression of salicylic acid and jasmonic acid pathways and photosynthesis parameters of sweet orange trees in response to acibenzolar-S-methyl
Darolt, Josiane Cecília; ; Wulff, Nelson Arno ; (Tropical Plant Pathology, 2020) [Artigo]
The use of resistance inducers may be a tool to assist in the management of citrus diseases. However, knowledge about how some inducers, such as the benzothiadiazoles, promote gene expression from the pathways involved in ... -
Environmentally sustainable and cost-effective bioleaching of aluminum from low-grade bauxite ore using marine-derived Aspergillus niger
Shah, Syed Sikandar; ; Sponchiado, Sandra Regina Pombeiro ; Bevilaqua, Denise (Hydrometallurgy, 2020) [Artigo]
In this study, an economical and sustainable bio-hydrometallurgical route was evaluated for the recovery of aluminum from low-grade bauxite using the marine-derived fungus Aspergillus niger. Firstly, four different solid ... -
Immobilized microbial nanoparticles for biosorption
; Silva, Debora D. V.; ; Almeida, Sâmilla G. C. ; Dussán, Kelly J. (Critical Reviews in Biotechnology, 2020) [Resenha]
Biosorption processes emerge as an economical and eco-friendly alternative technology for the removal of pollutants present in the environment. One biosorption process application is found in the immobilization of microbial ... -
Cathodic stripping voltammetric determination of β-cyfluthrin, a pyrethroid insecticide, using polished silver solid amalgam electrode
Silva, Caio César Gonçalves; Silva, Lucas Moreira ; e Silva, Beatriz Costa ; Garrido, Saulo Santesso ; Boldrin, Maria Valnice ; (Journal of Solid State Electrochemistry, 2020) [Artigo]
This work describes an electroanalytical procedure for determination of beta-cyfluthrin (βCF), a pyrethroid insecticide, using polished silver solid amalgam electrode (p-AgSAE) allied to a square-wave cathodic adsorptive ... -
Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation
de Oliveira, Larissa Ragozo Cardoso; Mimura, Luiza Ayumi Nishiyama ; Fraga-Silva, Thais Fernanda de Campos ; Ishikawa, Larissa Lumi Watanabe ; Fernandes, Ana Angélica Henrique ; Zorzella-Pezavento, Sofia Fernanda Gonçalves ; Sartori, Alexandrina (Frontiers in Pharmacology, 2020) [Artigo]
Multiple sclerosis (MS) is a progressive disease of the central nervous system (CNS) that involves damage to the myelin sheath surrounding axons. MS therapy is based on immunomodulatory drugs that reduce disease recurrence ... -
Antimicrobial activity of RP-1 peptide conjugate with ferrocene group
Costa, Natalia C.S.; Piccoli, Julia P. ; Santos-Filho, Norival A. ; Clementino, Leandro C. ; Fusco-Almeida, Ana M. ; De Annunzio, Sarah R. ; Fontana, Carla R. ; Verga, Juliane B.M. ; Eto, Silas F. ; Pizauro-Junior, João M. et al. (PLoS ONE, 2020) [Artigo]
Parasitic diseases are a neglected and serious problem, especially in underdeveloped countries. Among the major parasitic diseases, Leishmaniasis figures as an urgent challenge due to its high incidence and severity. At ...