Planejamento racional de fármacos baseado em produtos naturais
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Data
2001-02-01
Autores
Montanari, Carlos Alberto
Bolzani, Vanderlan da Silva [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Sociedade Brasileira de Química
Resumo
In the area of drug discovery, natural products represent a myriad of templates for new lead discovery. It is, however, most unlikely that the bioactive principle itself shall become a drug; it is much more likely that a medicinal chemistry project needs to be initiated as soon the potency or selectivity or specificity of the new natural product candidate has been disclosed. Brazil has an enormous biodiversity where just a few has been disclosed. Nevertheless, it urges to initiate a joint collaboration in order to circumvent a major breakdown linking between natural products and medicinal chemistry in this country. This paper is intended to encourage people to follow up one of the most pushing forward enterprise that needs to be settled: the pharmaceutical industry.
Descrição
Palavras-chave
natural products, medicinal chemistry, pharmaceutical industry
Como citar
Química Nova. Sociedade Brasileira de Química, v. 24, n. 1, p. 105-111, 2001.