An efficient and versatile synthesis of acylpolyamine spider toxins
Abstract
An efficient and versatile synthesis of acylpolyamine spider toxins was developed based on the structural classification of the Nephila and Nephilengys spider toxins using the 2-nitrobenzenesulfonamide protecting group. The naturally occurring toxins 1-5 representing each structural type have been efficiently synthesized by this method in a high overall yield with few steps. (C) 2002 Elsevier B.V. Ltd. All rights reserved.
How to cite this document
Nihei, K. et al. An efficient and versatile synthesis of acylpolyamine spider toxins. Bioorganic & Medicinal Chemistry Letters. Oxford: Pergamon-Elsevier B.V., v. 12, n. 3, p. 299-302, 2002. Available at: <http://hdl.handle.net/11449/34766>.
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