Voltammetric assay of albendazole in pharmaceutical dosage forms

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Data

2001-01-01

Autores

de Oliveira, M. F.
Stradiotto, Nelson Ramos [UNESP]

Título da Revista

ISSN da Revista

Título de Volume

Editor

Marcel Dekker Inc

Resumo

A simple, rapid inexpensive voltammetric method have been developed for the quantitative determination of albendazole (ABZ) as the pure assay, by direct dissolution of commercial tablets in HCl solutions. Studies with linear sweep (LSV), square-wave (SWV) and differential pulse voltammetry (DPV) were carried out ABZ in aqueous medium at a glassy carbon electrode. A well defined irreversible oxidation peak current was obtained at 1,00V vs. SCE. The method permits a precise quantitative determination of ABZ using the standard addition method. The detection limits for the three voltammetric techniques were found to be 3.0 x 10(-5) M (LSV), 6.2 x 10(-5) M (SWV) and 4.0 x 10(-5) M (DPV).

Descrição

Palavras-chave

albendazole, differential pulse, square wave, linear sweep

Como citar

Analytical Letters. New York: Marcel Dekker Inc., v. 34, n. 3, p. 377-387, 2001.