RSS 1.0Centro de Assistência Toxicológica (CEATOX) - Botucatu
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Circulating heme oxygenase-1: Not a predictor of preeclampsia but highly expressed in pregnant women who subsequently develop severe preeclampsia
Sandrim, Valéria C.
; Caldeira-Dias, Mayara ; ; ; ; (Oxidative Medicine and Cellular Longevity, 2018) [Artigo]
Preeclampsia is the major cause of maternal and fetal deaths worldwide. Circulating biomarker concentrations to predict preeclampsia must be determined. Therefore, the objective was to evaluate heme oxygenase-1 (HO-1) ... -
Tobacco influence in heavy metals levels in head and neck cancer cases
Bandeira, Celso Muller; de Almeida, Adriana Ávila ; ; Almeida, Alaor Aparecido ; de Figueiredo, Fellipe Augusto Tocchini ; Sandrim, Valeria Cristina ; ; Almeida, Janete Dias (Environmental Science and Pollution Research, 2018) [Artigo]
Heavy metals intoxication is known to be risk factors for various diseases, including cancer. These metals may be presented in food and soil as well as in leaf and tobacco smoke. The aim of this study was to correlate the ... -
Insecticidal activity of an essential oil of Tagetes patula L. (Asteraceae) on common bed bug Cimex lectularius L. and molecular docking of major compounds at the catalytic site of ClAChE1
Politi, Flávio Augusto Sanches; Nascimento, Juliana Damieli ; da Silva, Alexander Alves ; Moro, Isabela Jacob ; ; ; Pietro, Rosemeire Cristina Linhari Rodrigues ; Godinho, Antônio Francisco ; Furlan, Maysa (Parasitology Research, 2017) [Artigo]
Emerging resistance to insecticides has influenced pharmaceutical research and the search for alternatives to control the common bed bug Cimex lectularius. In this sense, natural products can play a major role. Tagetes ... -
Memory impairment due to fipronil pesticide exposure occurs at the GABAA receptor level, in rats
Godinho, Antonio Francisco; Chagas, Ana Carolina Souza ; Carvalho, Caio Cristóvão ; Horta, Daniel França ; De Fraia, Daniel ; Anselmo, Fabio ; Chaguri, João Leandro ; Faria, Caique Aparecido (Physiology and Behavior, 2016) [Artigo]
Fipronil (F) a pesticide considered of second generation cause various toxic effects in target and non-target organisms including humans in which provoke neurotoxicity, having the antagonism of gamma-amino butyric acid ... -
Exposure to fipronil elevates systolic blood pressure and disturbs related biomarkers in plasma of rats
Chaguri, Joao Leandro; Godinho, Antonio Francisco ; Horta, Daniel França ; Gonçalves-Rizzi, Victor Hugo ; Possomato-Vieira, Jose Sergio ; Nascimento, Regina Aparecida ; Dias-Junior, Carlos Alan (Environmental Toxicology and Pharmacology, 2016) [Artigo]
Recent reports show that fipronil affects non-target organisms, including environmental species populations and potentially humans. We aimed to examine if fipronil exposure affects the systolic blood pressure and related ... -
A snakebite caused by a bushmaster (Lachesis muta): report of a confirmed case in State of Pernambuco, Brazil
; Haddad Junior, Vidal (Revista Da Sociedade Brasileira De Medicina Tropical, 2015) [Artigo]
We report a case of envenomation caused by a bushmaster (Lachesis muta) in a male child in State of Pernambuco, Brazil. The victim showed discrete local manifestations, but presented altered blood coagulation 2 hours after ... -
Avaliação dos casos de intoxicações por agentes tóxicos no período de janeiro de 1998 a dezembro de 2002, no CEATOX Botucatu-SP
Olivo, Taylor Endrigo Toscano; Tahara, Adriana ; Oliveira, Alessandro Carvalho de ; Melachauskas, Camila de Oliveira ; Antonelli, Daniele Andreza ; Pinheiro, Fabriciano ; Beluche, Michel ; Ielo, Samuel Moraes ; Bissacot, Denise Zuccari ; Kempinas, Wilma De Grava (Congresso de Extensão Universitária, 2003) [Resumo]
Introdução: O CEATOX (Centro de Assistência Toxicológica) de Botucatu-SP é uma Unidade Auxiliar do Instituto de Biociências, UNESP. Uma das finalidades do CEATOX é prestar assistência toxicológica telefônica, pelos ... -
Avaliação dos casos e perfil dos pacientes intoxicados por agentes tóxicos em tentativas de suicídio e aborto
Contente, André Costa; Carvalho, Lídia Raquel de ; Kempinas, Wilma De Grava (Congresso de Extensão Universitária, 2003) [Resumo]
Introdução: O Centro de Assistência Toxicológica – CEATOX, de Botucatu, realiza, por intermédio de seus profissionais e plantonistas da Liga Acadêmica de Toxicologia, atendimento telefônico ininterrupto de casos de ... -
Prevenção ao uso de drogas de abuso
Cestari, Sílvia Helena; Leite, Alexandre Roberto ; Cafagni, Amanda Campos ; Almeida, Alaor Aparecido ; Kempinas, Wilma De Grava (Congresso de Extensão Universitária, 2003) [Resumo]
Introdução: Um dos maiores problemas entre os jovens é o consumo de drogas de abuso, que está começando cada vez mais cedo. Por isso, a sociedade necessita de iniciativas no sentido de esclarecer os usuários de drogas os ... -
Avaliação das informações telefônicas atendidas pelo CEATOX-Botucatu-SP sobre condutas de tratamento em casos de acidentes humanos causados por animais peçonhentos ou não, no período de 1999 a 2004
Garcia, Fernando Henrique Tosin; Mutti, Aníbal ; Galvanese, Bruno Soares ; Faria, Eduardo Petribu ; Sato, Frank Emerson Sussumo ; Milhan, Karen Raquel ; Cordelini, Sandra ; Bissacot, Denise Zuccari (Revista Ciência em Extensão, 2006) [Resumo]
Introdução: O CEATOX (Centro de Assistência Toxicológica) de Botucatu – SP realiza por intermédio de profissionais da Unidade e plantonistas dos Cursos de Medicina e Enfermagem (LAT: Liga Acadêmica de Toxicologia), atendimento ... -
Spontaneous mammary carcinomas in female dogs: association between immunohistochemical degrees of neoplasia aggressiveness and residual pyrethroids
Colodel, Marcia Moleta; Ferreira, Isabelle ; ; Almeida, Alaor Aparecido ; Lopes, Maria Denise ; Rocha, Noeme Sousa (Open Journal of Veterinary Medicine, 2012) [Artigo]
Of the tumors diagnosed in the female dogs have the highest mammary neoplasias incidence. These neoplasias can be influenced by environmental contaminants. Despite evidence of pyrethroid toxicity, carcinogenic potential ... -
Reproductive physiology, and physical and sexual development of female offspring born to diabetic dams
Spadotto, Raquel; Damasceno, Débora Cristina ; Godinho, Antônio F. ; ; ; Kempinas, Wilma De Grava (Arquivos Brasileiros de Endocrinologia e Metabologia, 2012) [Artigo]
Objectives: The objective of this study was to evaluate physical and sexual development and reproductive physiology in female rat offspring that developed in hyperglycemia conditions in utero and during lactation. Materials ... -
Correlations among antiangiogenic factors and trace elements in hypertensive disorders of pregnancy
; ; ; ; ; Sandrim, Valeria Cristina (Journal Of Trace Elements In Medicine And Biology, 2015) [Artigo]
Although a number of studies have measured circulating levels of some trace elements in preeclampsia (PE) and compared to healthy pregnant (HP), there is no consensus yet about the deficiency of some metals and development ... -
Metalloproteinase inhibition protects against reductions in circulating adrenomedullin during lead-induced acute hypertension
Nascimento, Regina Aparecida do; Mendes, Gabryella ; Possomato-Vieira, José Sérgio ; Gonçalves-Rizzi, Victor Hugo ; Kushima, Hélio ; Delella, Flavia Karina ; Dias-Junior, Carlos Alan (Basic & Clinical Pharmacology & Toxicology, 2015) [Artigo]
Intoxication with lead (Pb) results in increased blood pressure by mechanisms involving matrix metalloproteinases (MMPs). Recent findings have revealed that MMP type two (MMP-2) seems to cleave vasoactive peptides. This ... -
Permethrin chronic exposure alters motor coordination in rats: Effect of calcium supplementation and amlodipine
Godinho, A. F.; Stanzani, S. L. ; Ferreira, F. C. ; Braga, T. C. ; Silva, M. C. ; Chaguri, J. L. ; Dias-Junior, C. A. (Environmental Toxicology and Pharmacology, 2014) [Artigo]
Recently was observed that pyrethroids decrease motor coordination and that calcium channels can be important targets for this effect. To contribute with this observation, this work studied the motor coordination and ... -
Caffeine reduces cadmium accumulation in the organism and enhances the levels of antioxidant protein expression in the epididymis
Lacorte, Livia M.; Seiva, Fabio R.F. ; Rinaldi, Jaqueline C. ; Delella, Flavia K. ; Moroz, Andrei ; Sarobo, Carolina ; Godinho, Antonio F. ; ; Fernandes, Ana A.H. ; Felisbino, Sérgio L. (Reproductive Toxicology, 2013) [Artigo]
The aim of this study was to investigate the effects of caffeine (20. mg/L) intake on cadmium (15. mg/L) accumulation in the rat blood, testes, epididymis and prostate as well as cadmium-induced changes to the antioxidant ... -
Determination of calcium and magnesium in hydroethanolic extracts of propolis by atomic absorption flame spectrophotometry
; Almeida, A. A.; ; Almeida, Adelia Emilia de ; Chung, M. C. (Revista de Ciências Farmacêuticas Básica e Aplicada, 2008) [Artigo]
Propolis is a natural product collected by honeybees and has a large range of pharmacological activity, including antimicrobial, antitumoral, antioxidant and anti-inflammatory. Its use as a popular medicine is increasing ... -
Interaction between humic substances and metallic ions: A selectivity study of humic substances and their possible therapeutic application
Dos Santos, Ademir; Botero, Wander Gustavo ; Bellin, Iramaia Corrêa ; De Oliveira, Luciana Camargo ; Rocha, Julio Cesar ; Mendonça, André Gustavo Ribeiro ; Godinho, Antonio Francisco (Journal of the Brazilian Chemical Society, 2007) [Artigo]
The complexation capacity of humic substances extracted from peat samples taken from the Mogi River in Ribeirao Preto, SP, Brazil, was determined using metal ions (Al(III), Pb(II), Cr(VI) and Cd(II)), yielding the following ... -
Neonatal rat exposure to pyrethroid and organophosphate insecticides: A physiological and biochemical trial of progeny
Godinho, A. F.; Silva, D. A F ; Mercadante, A. ; Sartori, A. M A (Revista de Ciencias Farmaceuticas, 2004) [Artigo]
A manufactured product (Ectoplus®) composed by a cypermethrin (44.7%) and dichlorvos (4.2%) mixture was administered (10mg/kg/day, orally, by gavage) to pregnant rats, during the periods of gestation+lactation, gestation, ... -
Behavioural alterations provoked by prolonged calcitonin administration in rats
Arone, Ana Elisa F.; De Aguiar, Daniele Cristina ; Godinho, Antônio Francisco (Revista Brasileira de Toxicologia, 2003) [Artigo]
Present work investigated the effect of prolonged administration of salmon calcitonin, a hormone secreted by parafollicular cells from thyroid, on behavioural parameters of rats. Animals received calcitonin sc, 100 mUI/100 ...