RSS 1.0Centro de Assistência Toxicológica (CEATOX) - Botucatu
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Safety assessment of the ethanolic extract from Piper vicosanum yunck leaves in male rats
Jorge, Bárbara Campos
; ; Stein, Julia ; Reis, Ana Carolina Casali ; Moreira, Suyane da Silva ; ; ; ; Arena, Arielle Cristina (Phytomedicine Plus, 2022) [Artigo]
Background: Piper vicosanum (Piperaceae) is a species used in folk medicine mainly due to its anti-inflammatory and analgesic properties. However, the data available about its safety are still insufficient. Purpose: This ... -
Can maternal exposure to tamoxifen compromise sperm and behavioural parameters of male rat offspring?
; da Silva Moreira, Suyane; Zampieri, Gabriela Morelli ; Machado Pinheiro, Luísa ; Jorge, Bárbara Campos ; Casali Reis, Ana Carolina ; ; Arena, Arielle Cristina (Reproductive Toxicology, 2022) [Artigo]
Tamoxifen, a selective non-steroidal estrogen receptor modulator, is the standard adjuvant endocrine treatment for breast cancer. Since information on the risk of using tamoxifen during pregnancy is still scarce, this study ... -
Preeclampsia and Gestational Hypertension: Biochemical and Antioxidant Features in Vitro Might Help Understand Different Outcomes
Galvão, Victoria Elizabeth; ; Sandrim, Valeria Cristina (Revista Brasileira de Ginecologia e Obstetricia, 2021) [Artigo]
Objective Gestational hypertension (GH) is characterized by increased blood pressure after the 20 thgestational week; the presence of proteinuria and/or signs of end-organ damage indicate preeclampsia (PE). Heme oxygenase-1 ... -
Lowland tapir exposure to pesticides and metals in the Brazilian Cerrado
; ; ; Godinho, Antonio Francisco; (Wildlife Research, 2020) [Artigo]
Context. The Cerrado is a Global Biodiversity Hotspot as well as Brazil's main frontier for large-scale agriculture and livestock production, making it one of the most threatened biomes in the country. Brazil is one of the ... -
Parental exposure to benzo(a)pyrene in the peripubertal period impacts reproductive aspects of the F1 generation in rats
Jorge, Bárbara Campos; Reis, Ana Carolina Casali ; Stein, Julia ; Balin, Paola da Silva ; Sterde, Érika Tissiana ; Barbosa, Mariana Gazoli ; de Aquino, Ariana Musa ; ; Arena, Arielle Cristina (Reproductive Toxicology, 2021) [Artigo]
Benzo(a)pyrene (BaP) is an ubiquitous environmental pollutant which can lead to adverse effects on male reproduction. However, the persistence of these changes on a multigenerational scale has not been sufficiently explored. ... -
Effects of benzo(a)pyrene at environmentally relevant doses on embryo-fetal development in rats
da Silva Moreira, Suyane; de Lima Inocêncio, Leonardo Cesar ; Jorge, Bárbara Campos ; Reis, Ana Carolina Casali ; ; Arena, Arielle Cristina (Environmental Toxicology, 2021) [Artigo]
Studies have demonstrated that Benzo(a)Pyrene (BaP), a polycyclic aromatic hydrocarbon ubiquituous in the environment, can cause teratogenic effects. Since the majority of studies used in vitro models or high doses of BaP, ... -
Ibuprofen compromises sexual behavior and fertility in female rats exposed during the perinatal period
Jorge, Bárbara Campos; Balin, Paola da Silva ; Carneiro, Giovanna de Brito ; Belleti, Rafael ; Reis, Ana Carolina Casali ; Stein, Julia ; ; ; Arena, Arielle Cristina (Toxicological and Environmental Chemistry, 2020) [Artigo]
The influence of ibuprofen exposure during the perinatal period, when the brain sexual differentiation process occurs, on the sexual behavior and fertility of female offspring Wistar rats has been evaluated. Ibuprofen was ... -
Exposure to benzo(a)pyrene from juvenile period to peripubertal impairs male reproductive parameters in adult rats
Jorge, Bárbara Campos; Reis, Ana Carolina Casali ; Sterde, Érika Tissiana ; Balin, Paola da Silva ; Scarano, Wellerson Rodrigo ; ; Arena, Arielle Cristina (Chemosphere, 2021) [Artigo]
Benzo(a)pyrene (BaP) is a persistent organic pollutant and endocrine disruptor that can compromise the steroidogenesis process by interacting with the StAR protein, causing adverse effects on male reproduction. However, ... -
Characterization of leachate produced by a landfill and its influence on a sewage treatment plant
Destro, Guilherme E.; Junior, Sergio S. Braga ; Tadayozzi, Yasmin S. ; Almeida, Alaor A. ; ; Forti, Juliane C. (Environmental Quality Management, 2020) [Artigo]
Although landfills are generally an environmentally safe option for the disposal of solid waste, the treatment and management of landfill leachate are still critical. The aim of this work was to study through physical-chemical ... -
Circulating heme oxygenase-1: Not a predictor of preeclampsia but highly expressed in pregnant women who subsequently develop severe preeclampsia
Sandrim, Valéria C.; Caldeira-Dias, Mayara ; ; ; ; (Oxidative Medicine and Cellular Longevity, 2018) [Artigo]
Preeclampsia is the major cause of maternal and fetal deaths worldwide. Circulating biomarker concentrations to predict preeclampsia must be determined. Therefore, the objective was to evaluate heme oxygenase-1 (HO-1) ... -
Tobacco influence in heavy metals levels in head and neck cancer cases
Bandeira, Celso Muller; de Almeida, Adriana Ávila ; ; Almeida, Alaor Aparecido ; de Figueiredo, Fellipe Augusto Tocchini ; Sandrim, Valeria Cristina ; ; Almeida, Janete Dias (Environmental Science and Pollution Research, 2018) [Artigo]
Heavy metals intoxication is known to be risk factors for various diseases, including cancer. These metals may be presented in food and soil as well as in leaf and tobacco smoke. The aim of this study was to correlate the ... -
Insecticidal activity of an essential oil of Tagetes patula L. (Asteraceae) on common bed bug Cimex lectularius L. and molecular docking of major compounds at the catalytic site of ClAChE1
Politi, Flávio Augusto Sanches; Nascimento, Juliana Damieli ; da Silva, Alexander Alves ; Moro, Isabela Jacob ; ; ; Pietro, Rosemeire Cristina Linhari Rodrigues ; Godinho, Antônio Francisco ; Furlan, Maysa (Parasitology Research, 2017) [Artigo]
Emerging resistance to insecticides has influenced pharmaceutical research and the search for alternatives to control the common bed bug Cimex lectularius. In this sense, natural products can play a major role. Tagetes ... -
Memory impairment due to fipronil pesticide exposure occurs at the GABAA receptor level, in rats
Godinho, Antonio Francisco; Chagas, Ana Carolina Souza ; Carvalho, Caio Cristóvão ; Horta, Daniel França ; De Fraia, Daniel ; Anselmo, Fabio ; Chaguri, João Leandro ; Faria, Caique Aparecido (Physiology and Behavior, 2016) [Artigo]
Fipronil (F) a pesticide considered of second generation cause various toxic effects in target and non-target organisms including humans in which provoke neurotoxicity, having the antagonism of gamma-amino butyric acid ... -
Exposure to fipronil elevates systolic blood pressure and disturbs related biomarkers in plasma of rats
Chaguri, Joao Leandro; Godinho, Antonio Francisco ; Horta, Daniel França ; Gonçalves-Rizzi, Victor Hugo ; Possomato-Vieira, Jose Sergio ; Nascimento, Regina Aparecida ; Dias-Junior, Carlos Alan (Environmental Toxicology and Pharmacology, 2016) [Artigo]
Recent reports show that fipronil affects non-target organisms, including environmental species populations and potentially humans. We aimed to examine if fipronil exposure affects the systolic blood pressure and related ... -
A snakebite caused by a bushmaster (Lachesis muta): report of a confirmed case in State of Pernambuco, Brazil
; Haddad Junior, Vidal (Revista Da Sociedade Brasileira De Medicina Tropical, 2015) [Artigo]
We report a case of envenomation caused by a bushmaster (Lachesis muta) in a male child in State of Pernambuco, Brazil. The victim showed discrete local manifestations, but presented altered blood coagulation 2 hours after ... -
Avaliação dos casos de intoxicações por agentes tóxicos no período de janeiro de 1998 a dezembro de 2002, no CEATOX Botucatu-SP
Olivo, Taylor Endrigo Toscano; Tahara, Adriana ; Oliveira, Alessandro Carvalho de ; Melachauskas, Camila de Oliveira ; Antonelli, Daniele Andreza ; Pinheiro, Fabriciano ; Beluche, Michel ; Ielo, Samuel Moraes ; Bissacot, Denise Zuccari ; Kempinas, Wilma De Grava (Congresso de Extensão Universitária, 2003) [Resumo]
Introdução: O CEATOX (Centro de Assistência Toxicológica) de Botucatu-SP é uma Unidade Auxiliar do Instituto de Biociências, UNESP. Uma das finalidades do CEATOX é prestar assistência toxicológica telefônica, pelos ... -
Prevenção ao uso de drogas de abuso
Cestari, Sílvia Helena; Leite, Alexandre Roberto ; Cafagni, Amanda Campos ; Almeida, Alaor Aparecido ; Kempinas, Wilma De Grava (Congresso de Extensão Universitária, 2003) [Resumo]
Introdução: Um dos maiores problemas entre os jovens é o consumo de drogas de abuso, que está começando cada vez mais cedo. Por isso, a sociedade necessita de iniciativas no sentido de esclarecer os usuários de drogas os ... -
Avaliação dos casos e perfil dos pacientes intoxicados por agentes tóxicos em tentativas de suicídio e aborto
Contente, André Costa; Carvalho, Lídia Raquel de ; Kempinas, Wilma De Grava (Congresso de Extensão Universitária, 2003) [Resumo]
Introdução: O Centro de Assistência Toxicológica – CEATOX, de Botucatu, realiza, por intermédio de seus profissionais e plantonistas da Liga Acadêmica de Toxicologia, atendimento telefônico ininterrupto de casos de ... -
Avaliação das informações telefônicas atendidas pelo CEATOX-Botucatu-SP sobre condutas de tratamento em casos de acidentes humanos causados por animais peçonhentos ou não, no período de 1999 a 2004
Garcia, Fernando Henrique Tosin; Mutti, Aníbal ; Galvanese, Bruno Soares ; Faria, Eduardo Petribu ; Sato, Frank Emerson Sussumo ; Milhan, Karen Raquel ; Cordelini, Sandra ; Bissacot, Denise Zuccari (Revista Ciência em Extensão, 2006) [Resumo]
Introdução: O CEATOX (Centro de Assistência Toxicológica) de Botucatu – SP realiza por intermédio de profissionais da Unidade e plantonistas dos Cursos de Medicina e Enfermagem (LAT: Liga Acadêmica de Toxicologia), atendimento ... -
Spontaneous mammary carcinomas in female dogs: association between immunohistochemical degrees of neoplasia aggressiveness and residual pyrethroids
Colodel, Marcia Moleta; Ferreira, Isabelle ; ; Almeida, Alaor Aparecido ; Lopes, Maria Denise ; Rocha, Noeme Sousa (Open Journal of Veterinary Medicine, 2012) [Artigo]
Of the tumors diagnosed in the female dogs have the highest mammary neoplasias incidence. These neoplasias can be influenced by environmental contaminants. Despite evidence of pyrethroid toxicity, carcinogenic potential ...