Recent Submissions

  • Safety assessment of the ethanolic extract from Piper vicosanum yunck leaves in male rats

    Jorge, Bárbara Campos Autor UNESP; Júnior, Armando Jorge; Stein, Julia Autor UNESP; Reis, Ana Carolina Casali Autor UNESP; Moreira, Suyane da Silva Autor UNESP; Manoel, Beatriz de Matos; Mota, Jonas da Silva; Kassuya, Cândida Aparecida Leite; Arena, Arielle Cristina Autor UNESP (Phytomedicine Plus, 2022) [Artigo]
    Background: Piper vicosanum (Piperaceae) is a species used in folk medicine mainly due to its anti-inflammatory and analgesic properties. However, the data available about its safety are still insufficient. Purpose: This ...
  • Can maternal exposure to tamoxifen compromise sperm and behavioural parameters of male rat offspring?

    de Matos Manoel, Beatriz; da Silva Moreira, Suyane Autor UNESP; Zampieri, Gabriela Morelli Autor UNESP; Machado Pinheiro, Luísa Autor UNESP; Jorge, Bárbara Campos Autor UNESP; Casali Reis, Ana Carolina Autor UNESP; Leite Kassuya, Cândida Aparecida; Arena, Arielle Cristina Autor UNESP (Reproductive Toxicology, 2022) [Artigo]
    Tamoxifen, a selective non-steroidal estrogen receptor modulator, is the standard adjuvant endocrine treatment for breast cancer. Since information on the risk of using tamoxifen during pregnancy is still scarce, this study ...
  • Preeclampsia and Gestational Hypertension: Biochemical and Antioxidant Features in Vitro Might Help Understand Different Outcomes

    Galvão, Victoria Elizabeth Autor UNESP; Cavalli, Ricardo Carvalho; Sandrim, Valeria Cristina Autor UNESP (Revista Brasileira de Ginecologia e Obstetricia, 2021) [Artigo]
    Objective Gestational hypertension (GH) is characterized by increased blood pressure after the 20 thgestational week; the presence of proteinuria and/or signs of end-organ damage indicate preeclampsia (PE). Heme oxygenase-1 ...
  • Lowland tapir exposure to pesticides and metals in the Brazilian Cerrado

    Medici, Emília P.; Fernandes-Santos, Renata Carolina; Testa-José, Caroline; Godinho, Antonio Francisco Autor UNESP; Brand, Anne-Fleur (Wildlife Research, 2020) [Artigo]
    Context. The Cerrado is a Global Biodiversity Hotspot as well as Brazil's main frontier for large-scale agriculture and livestock production, making it one of the most threatened biomes in the country. Brazil is one of the ...
  • Parental exposure to benzo(a)pyrene in the peripubertal period impacts reproductive aspects of the F1 generation in rats

    Jorge, Bárbara Campos Autor UNESP; Reis, Ana Carolina Casali Autor UNESP; Stein, Julia Autor UNESP; Balin, Paola da Silva Autor UNESP; Sterde, Érika Tissiana Autor UNESP; Barbosa, Mariana Gazoli Autor UNESP; de Aquino, Ariana Musa Autor UNESP; Kassuya, Cândida Aparecida Leite; Arena, Arielle Cristina Autor UNESP (Reproductive Toxicology, 2021) [Artigo]
    Benzo(a)pyrene (BaP) is an ubiquitous environmental pollutant which can lead to adverse effects on male reproduction. However, the persistence of these changes on a multigenerational scale has not been sufficiently explored. ...
  • Effects of benzo(a)pyrene at environmentally relevant doses on embryo-fetal development in rats

    da Silva Moreira, Suyane Autor UNESP; de Lima Inocêncio, Leonardo Cesar Autor UNESP; Jorge, Bárbara Campos Autor UNESP; Reis, Ana Carolina Casali Autor UNESP; Hisano, Hamilton; Arena, Arielle Cristina Autor UNESP (Environmental Toxicology, 2021) [Artigo]
    Studies have demonstrated that Benzo(a)Pyrene (BaP), a polycyclic aromatic hydrocarbon ubiquituous in the environment, can cause teratogenic effects. Since the majority of studies used in vitro models or high doses of BaP, ...
  • Ibuprofen compromises sexual behavior and fertility in female rats exposed during the perinatal period

    Jorge, Bárbara Campos Autor UNESP; Balin, Paola da Silva Autor UNESP; Carneiro, Giovanna de Brito Autor UNESP; Belleti, Rafael Autor UNESP; Reis, Ana Carolina Casali Autor UNESP; Stein, Julia Autor UNESP; de Barros, Aline Lima; Kassuya, Cândida Aparecida Leite; Arena, Arielle Cristina Autor UNESP (Toxicological and Environmental Chemistry, 2020) [Artigo]
    The influence of ibuprofen exposure during the perinatal period, when the brain sexual differentiation process occurs, on the sexual behavior and fertility of female offspring Wistar rats has been evaluated. Ibuprofen was ...
  • Exposure to benzo(a)pyrene from juvenile period to peripubertal impairs male reproductive parameters in adult rats

    Jorge, Bárbara Campos Autor UNESP; Reis, Ana Carolina Casali Autor UNESP; Sterde, Érika Tissiana Autor UNESP; Balin, Paola da Silva Autor UNESP; Scarano, Wellerson Rodrigo Autor UNESP; Hisano, Hamilton; Arena, Arielle Cristina Autor UNESP (Chemosphere, 2021) [Artigo]
    Benzo(a)pyrene (BaP) is a persistent organic pollutant and endocrine disruptor that can compromise the steroidogenesis process by interacting with the StAR protein, causing adverse effects on male reproduction. However, ...
  • Characterization of leachate produced by a landfill and its influence on a sewage treatment plant

    Destro, Guilherme E. Autor UNESP; Junior, Sergio S. Braga Autor UNESP; Tadayozzi, Yasmin S. Autor UNESP; Almeida, Alaor A. Autor UNESP; Chaves, Andrea R.; Forti, Juliane C. Autor UNESP (Environmental Quality Management, 2020) [Artigo]
    Although landfills are generally an environmentally safe option for the disposal of solid waste, the treatment and management of landfill leachate are still critical. The aim of this work was to study through physical-chemical ...
  • Circulating heme oxygenase-1: Not a predictor of preeclampsia but highly expressed in pregnant women who subsequently develop severe preeclampsia

    Sandrim, Valéria C. Autor UNESP; Caldeira-Dias, Mayara Autor UNESP; Bettiol, Heloisa; Barbieri, Marco Antonio; Cardoso, Viviane Cunha; Cavalli, Ricardo Carvalho (Oxidative Medicine and Cellular Longevity, 2018) [Artigo]
    Preeclampsia is the major cause of maternal and fetal deaths worldwide. Circulating biomarker concentrations to predict preeclampsia must be determined. Therefore, the objective was to evaluate heme oxygenase-1 (HO-1) ...
  • Tobacco influence in heavy metals levels in head and neck cancer cases

    Bandeira, Celso Muller Autor UNESP; de Almeida, Adriana Ávila Autor UNESP; Carta, Celina Faig Lima; Almeida, Alaor Aparecido Autor UNESP; de Figueiredo, Fellipe Augusto Tocchini Autor UNESP; Sandrim, Valeria Cristina Autor UNESP; Gonçalves, Antonio José; Almeida, Janete Dias Autor UNESP (Environmental Science and Pollution Research, 2018) [Artigo]
    Heavy metals intoxication is known to be risk factors for various diseases, including cancer. These metals may be presented in food and soil as well as in leaf and tobacco smoke. The aim of this study was to correlate the ...
  • Insecticidal activity of an essential oil of Tagetes patula L. (Asteraceae) on common bed bug Cimex lectularius L. and molecular docking of major compounds at the catalytic site of ClAChE1

    Politi, Flávio Augusto Sanches Autor UNESP; Nascimento, Juliana Damieli Autor UNESP; da Silva, Alexander Alves Autor UNESP; Moro, Isabela Jacob Autor UNESP; Garcia, Mariana Lopes; Guido, Rafael Victório Carvalho; Pietro, Rosemeire Cristina Linhari Rodrigues Autor UNESP; Godinho, Antônio Francisco Autor UNESP; Furlan, Maysa Autor UNESP (Parasitology Research, 2017) [Artigo]
    Emerging resistance to insecticides has influenced pharmaceutical research and the search for alternatives to control the common bed bug Cimex lectularius. In this sense, natural products can play a major role. Tagetes ...
  • Memory impairment due to fipronil pesticide exposure occurs at the GABAA receptor level, in rats

    Godinho, Antonio Francisco Autor UNESP; Chagas, Ana Carolina Souza Autor UNESP; Carvalho, Caio Cristóvão Autor UNESP; Horta, Daniel França Autor UNESP; De Fraia, Daniel Autor UNESP; Anselmo, Fabio Autor UNESP; Chaguri, João Leandro Autor UNESP; Faria, Caique Aparecido Autor UNESP (Physiology and Behavior, 2016) [Artigo]
    Fipronil (F) a pesticide considered of second generation cause various toxic effects in target and non-target organisms including humans in which provoke neurotoxicity, having the antagonism of gamma-amino butyric acid ...
  • Exposure to fipronil elevates systolic blood pressure and disturbs related biomarkers in plasma of rats

    Chaguri, Joao Leandro Autor UNESP; Godinho, Antonio Francisco Autor UNESP; Horta, Daniel França Autor UNESP; Gonçalves-Rizzi, Victor Hugo Autor UNESP; Possomato-Vieira, Jose Sergio Autor UNESP; Nascimento, Regina Aparecida Autor UNESP; Dias-Junior, Carlos Alan Autor UNESP (Environmental Toxicology and Pharmacology, 2016) [Artigo]
    Recent reports show that fipronil affects non-target organisms, including environmental species populations and potentially humans. We aimed to examine if fipronil exposure affects the systolic blood pressure and related ...
  • A snakebite caused by a bushmaster (Lachesis muta): report of a confirmed case in State of Pernambuco, Brazil

    Santana de Lima, Pedro Henrique; Haddad Junior, Vidal Autor UNESP (Revista Da Sociedade Brasileira De Medicina Tropical, 2015) [Artigo]
    We report a case of envenomation caused by a bushmaster (Lachesis muta) in a male child in State of Pernambuco, Brazil. The victim showed discrete local manifestations, but presented altered blood coagulation 2 hours after ...
  • Avaliação dos casos de intoxicações por agentes tóxicos no período de janeiro de 1998 a dezembro de 2002, no CEATOX Botucatu-SP

    Olivo, Taylor Endrigo Toscano Autor UNESP; Tahara, Adriana Autor UNESP; Oliveira, Alessandro Carvalho de Autor UNESP; Melachauskas, Camila de Oliveira Autor UNESP; Antonelli, Daniele Andreza Autor UNESP; Pinheiro, Fabriciano Autor UNESP; Beluche, Michel Autor UNESP; Ielo, Samuel Moraes Autor UNESP; Bissacot, Denise Zuccari Autor UNESP; Kempinas, Wilma De Grava Autor UNESP (Congresso de Extensão Universitária, 2003) [Resumo]
    Introdução: O CEATOX (Centro de Assistência Toxicológica) de Botucatu-SP é uma Unidade Auxiliar do Instituto de Biociências, UNESP. Uma das finalidades do CEATOX é prestar assistência toxicológica telefônica, pelos ...
  • Avaliação dos casos e perfil dos pacientes intoxicados por agentes tóxicos em tentativas de suicídio e aborto

    Contente, André Costa Autor UNESP; Carvalho, Lídia Raquel de Autor UNESP; Kempinas, Wilma De Grava Autor UNESP (Congresso de Extensão Universitária, 2003) [Resumo]
    Introdução: O Centro de Assistência Toxicológica – CEATOX, de Botucatu, realiza, por intermédio de seus profissionais e plantonistas da Liga Acadêmica de Toxicologia, atendimento telefônico ininterrupto de casos de ...
  • Prevenção ao uso de drogas de abuso

    Cestari, Sílvia Helena Autor UNESP; Leite, Alexandre Roberto Autor UNESP; Cafagni, Amanda Campos Autor UNESP; Almeida, Alaor Aparecido Autor UNESP; Kempinas, Wilma De Grava Autor UNESP (Congresso de Extensão Universitária, 2003) [Resumo]
    Introdução: Um dos maiores problemas entre os jovens é o consumo de drogas de abuso, que está começando cada vez mais cedo. Por isso, a sociedade necessita de iniciativas no sentido de esclarecer os usuários de drogas os ...
  • Avaliação das informações telefônicas atendidas pelo CEATOX-Botucatu-SP sobre condutas de tratamento em casos de acidentes humanos causados por animais peçonhentos ou não, no período de 1999 a 2004

    Garcia, Fernando Henrique Tosin Autor UNESP; Mutti, Aníbal Autor UNESP; Galvanese, Bruno Soares Autor UNESP; Faria, Eduardo Petribu Autor UNESP; Sato, Frank Emerson Sussumo Autor UNESP; Milhan, Karen Raquel Autor UNESP; Cordelini, Sandra Autor UNESP; Bissacot, Denise Zuccari Autor UNESP (Revista Ciência em Extensão, 2006) [Resumo]
    Introdução: O CEATOX (Centro de Assistência Toxicológica) de Botucatu – SP realiza por intermédio de profissionais da Unidade e plantonistas dos Cursos de Medicina e Enfermagem (LAT: Liga Acadêmica de Toxicologia), atendimento ...
  • Spontaneous mammary carcinomas in female dogs: association between immunohistochemical degrees of neoplasia aggressiveness and residual pyrethroids

    Colodel, Marcia Moleta Autor UNESP; Ferreira, Isabelle Autor UNESP; Martins, Vera Maria Villamil; Almeida, Alaor Aparecido Autor UNESP; Lopes, Maria Denise Autor UNESP; Rocha, Noeme Sousa Autor UNESP (Open Journal of Veterinary Medicine, 2012) [Artigo]
    Of the tumors diagnosed in the female dogs have the highest mammary neoplasias incidence. These neoplasias can be influenced by environmental contaminants. Despite evidence of pyrethroid toxicity, carcinogenic potential ...

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