Transformación de leucoplasia verrugosa proliferativa en carcinoma oral: diez años de seguimiento
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The authors present a case of proliferative verrucous leukoplakia (PVL) in a 78-year-old man. It was initially presented as leukoplakia on the tongue but a microscopic investigation in 1991 revealed it to be a mild epithelial dysplasia. After 5 years of follow-up, the lesion presented changes in size and location, and a recidivant behavior. In 1996, a red granular and indurated area that appeared on the tongue was found to be a microinvasive squamous cell carcinoma when microscopically investigated. After a review of the clinicopathologic behavior of this entity, the authors concluded that it was a typical PVL, whose diagnosis is difficult and retrospective, as indicated by others. The authors emphasize the importance of periodic detailed clinical and histological examination of this type of lesions in order to detect early signs of malignancy.
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Dysplasia Epithelial hyperplasia Papillomatosis Proliferative verrucous leukoplakia Squamous cell carcinoma aged case report clinical examination dysplasia epithelium hyperplasia follow up histology human leukoplakia male malignant transformation mouth carcinoma papillomatosis proliferative verrucous leukoplakia review squamous cell carcinoma Aged Carcinoma, Squamous Cell Cell Transformation, Neoplastic Follow-Up Studies Humans Leukoplakia, Oral Male Mouth Neoplasms Time Factors
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Espanhol
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Medicina Oral, v. 9, n. 3, p. 229-233, 2004.
