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dc.contributor.authorSiloto, E. V. [UNESP]
dc.contributor.authorOliveira, E. F A [UNESP]
dc.contributor.authorSartori, José Roberto [UNESP]
dc.contributor.authorFascina, V. B. [UNESP]
dc.contributor.authorMartins, B. A B [UNESP]
dc.contributor.authorLedoux, D. R.
dc.contributor.authorRottinghaus, G. E.
dc.contributor.authorSartori, D. R S [UNESP]
dc.date.accessioned2014-05-27T11:30:07Z
dc.date.available2014-05-27T11:30:07Z
dc.date.issued2013-08-01
dc.identifierhttp://ps.oxfordjournals.org/content/92/8/2077.abstract
dc.identifier.citationPoultry Science, v. 92, n. 8, p. 2077-2083, 2013.
dc.identifier.issn0032-5791
dc.identifier.issn1525-3171
dc.identifier.urihttp://hdl.handle.net/11449/76200
dc.description.abstractAflatoxins (AF) and fumonisins (FU) are a major problem faced by poultry farmers, leading to huge economic losses. This experiment was conducted to determine the effects of AF (1 mg/kg of feed) and FU (25 mg/kg of feed), singly or in combination, on the lipid metabolism in commercial layers and investigate the efficacy of a commercial binder (2 kg/t of feed) on reducing the toxic effects of these mycotoxins. A total of 168 Hisex Brown layer hens, 37 wk of age, were randomized into a 3 × 2 + 1 factorial arrangement (3 diets with no binder containing AF, FU, and AF+FU; 3 diets with binder containing AF, FU, and AF+FU; and a control diet with no mycotoxins and binders), totaling 7 treatments. The hens contaminated with AF showed the characteristic effects of aflatoxicosis, such as a yellow liver, resulting from the accumulation of liver fat, lower values of plasma very low-density lipoprotein and triglycerides, and higher relative weight of the kidneys and liver. Hepatotoxic and nephrotoxic effects of FU were not observed in this study. On the other hand, the FU caused a reduction in small intestine length and an increase in abdominal fat deposition. The glucan-based binder prevented some of the deleterious effects of these mycotoxins, particularly the effects of AF on hepatic lipid metabolism, kidney relative weight, and FU in the small intestine. © 2013 Poultry Science Association Inc.en
dc.description.sponsorshipAlltech do Brasil, Curitiba
dc.format.extent2077-2083
dc.language.isoeng
dc.relation.ispartofPoultry Science
dc.sourceScopus
dc.subjectAflatoxin
dc.subjectBinder
dc.subjectFumonisin
dc.subjectLaying hen
dc.subjectLipid metabolism
dc.titleLipid metabolism of commercial layers fed diets containing aflatoxin, fumonisin, and a binderen
dc.typeArtigo
dcterms.licensehttp://www.oxfordjournals.org/access_purchase/self-archiving_policyb.html
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversity of Missouri
dc.description.affiliationDepartamento de Fisiologia Instituto de Biocências Universidade Estadual Paulista (UNESP), Campus de Botucatu, Botucatu, SP, 18.618-970
dc.description.affiliationDepartamento de Melhoramento e Nutrição Animal Universidade Estadual Paulista (UNESP),Campus de Botucatu, Botucatu, SP, 18.618-970
dc.description.affiliationDivision of Animal Sciences University of Missouri, Columbia 65211
dc.description.affiliationVeterinary Medical Diagnostic Laboratory University of Missouri, Columbia 65211
dc.description.affiliationUnespDepartamento de Fisiologia Instituto de Biocências Universidade Estadual Paulista (UNESP), Campus de Botucatu, Botucatu, SP, 18.618-970
dc.description.affiliationUnespDepartamento de Melhoramento e Nutrição Animal Universidade Estadual Paulista (UNESP),Campus de Botucatu, Botucatu, SP, 18.618-970
dc.identifier.wosWOS:000322014500015
dc.rights.accessRightsAcesso restrito
dc.identifier.scopus2-s2.0-84880593556
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt
dc.identifier.lattes5272388662903892
unesp.author.lattes5272388662903892
unesp.author.orcid0000-0003-2691-8250[8]
dc.relation.ispartofjcr2.216
dc.relation.ispartofsjr1,112
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