RSS 1.0Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP) - Botucatu
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Recent Submissions
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Apilic antivenom, a new treatment for bee attacks, is effective in preclinical studies
(Toxicon : official journal of the International Society on Toxinology, 2020) [Artigo] -
Physical-chemical characterization of carbon nanotubes-hydroxyapatite nanocomposites with fibrin sealant derived from snake venom
(Toxicon : official journal of the International Society on Toxinology, 2020) [Artigo] -
Clinical and Therapeutic Aspects of Brazilian Native Bothrops Envenomation in Nine Horses
Ferreira, Júlia F.
; Albuquerque, Ana Luisa H. ; Amorim, Rogerio M. ; Ferreira, Rui S. ; Takahira, Regina K. ; Borges, Alexandre S. ; Oliveira-Filho, Jose P. (Journal of Equine Veterinary Science, 2020) [Artigo]
In this retrospective study, clinical records of nine horses with a diagnosis of Bothrops envenomation were investigated. The accidents were classified as severe (5/9), moderate (2/9), or mild (2/9) according to the adapted ... -
Neuroprotection and immunomodulation by dimethyl fumarate and a heterologous fibrin biopolymer after ventral root avulsion and reimplantation
; ; Barraviera, Benedito; Ferreira, Rui Seabra ; (Journal of Venomous Animals and Toxins Including Tropical Diseases, 2020) [Artigo]
Background: Ventral root avulsion (VRA) is an experimental approach in which there is an abrupt separation of the motor roots from the surface of the spinal cord. As a result, most of the axotomized motoneurons degenerate ... -
Proteomic analyses unraveling water stress response in two Eucalyptus species originating from contrasting environments for aridity
; ; Rossini, Bruno César; Marino, Celso Luís ; dos Santos, Lucilene Delazari ; (Molecular Biology Reports, 2020) [Artigo]
Eucalyptus are widely cultivated in several regions of the world due to their adaptability to different climatic conditions and amenable to tree breeding programs. With changes in environmental conditions pointing to an ... -
Metalloproteomic Strategies for Identifying Proteins as Biomarkers of Mercury Exposure in Serrasalmus rhombeus from the Amazon Region
de Queiroz, João Vitor; Cavecci-Mendonça, Bruna ; Vieira, José Cavalcante Souza ; Martins, Renata Aparecida ; de Almeida Assunção, Andrey Sávio ; Cavallini, Nubya Gonçalves ; dos Santos, Felipe André ; de Magalhães Padilha, Pedro (Biological Trace Element Research, 2020) [Artigo]
This manuscript describes the results of a metalloproteomic study of mercury in samples of muscle and liver tissue of the species Serrasalmus rhombeus, popularly known as black piranha and characterised as the most voracious ... -
Glutaredoxin-like protein (GLP)—a novel bacteria sulfurtransferase that protects cells against cyanide and oxidative stresses
de Paula, Carla Peres; dos Santos, Melina Cardoso ; Tairum, Carlos A. ; Breyer, Carlos Alexandre ; ; Toyama, Marcos Hikari ; Mori, Gustavo Maruyama ; de Oliveira, Marcos Antonio (Applied Microbiology and Biotechnology, 2020) [Artigo]
The pathogen Xylella fastidiosa belongs to the Xanthomonadaceae family, a large group of Gram-negative bacteria that cause diseases in many economically important crops. A predicted gene, annotated as glutaredoxin-like ... -
Improved production of the recombinant phospholipase A1 from Polybia paulista wasp venom expressed in bacterial cells for use in routine diagnostics
Perez-Riverol, Amilcar; ; ; dos Santos-Pinto, Jose Roberto Aparecido ; Esteves, Franciele Grego ; Bazon, Murilo Luiz ; ; Palma, Mario Sergio ; Brochetto-Braga, Márcia Regina (3 Biotech, 2020) [Artigo]
Phospholipase A1 (PLA1) is one of the three major allergens identified in the venom of P. paulista (Hymenoptera: Vespidae), a clinically relevant wasp from southeastern Brazil. The recombinant form of this allergen (rPoly ... -
Photobiomodulation therapy associated with heterologous fibrin biopolymer and bovine bone matrix helps to reconstruct long bones
; ; ; ; ; Júnior, Rui Seabra Ferreira; Barraviera, Benedito ; Cassaro, Claudia Vilalva ; ; et al. (Biomolecules, 2020) [Artigo]
Bone defects cause aesthetic and functional changes that affect the social, economic and especially the emotional life of human beings. This complication stimulates the scientific community to investigate strategies aimed ... -
Epididymal protease inhibitor (EPPIN) is a protein hub for seminal vesicle-secreted protein SVS2 binding in mouse spermatozoa
Mariani, Noemia A.P.; Camara, Aline C. ; Silva, Alan Andrew S. ; Raimundo, Tamiris R.F. ; Andrade, Juliana J. ; Andrade, Alexandre D. ; Rossini, Bruno C. ; Marino, Celso L. ; Kushima, Hélio ; Santos, Lucilene D. et al. (Molecular and Cellular Endocrinology, 2020) [Artigo]
EPPIN is a sperm-surface drug target for male contraception. Here we investigated EPPIN-interacting proteins in mouse spermatozoa. We showed that EPPIN is an androgen-dependent gene, expressed in the testis and epididymis, ... -
Proteomic analysis and antibacterial resistance mechanisms of Salmonella Enteritidis submitted to the inhibitory effect of Origanum vulgare essential oil, thymol and carvacrol
Barbosa, Lidiane Nunes; Alves, Fernanda Cristina Bergamo ; Andrade, Bruna Fernanda Murbach Teles ; Albano, Mariana ; Rall, Vera Lucia Mores ; Fernandes, Ana Angélica Henrique ; ; ; de Pontes, Leticia Gomes ; dos Santos, Lucilene Delazari et al. (Journal of Proteomics, 2020) [Artigo]
Biological properties of natural products are an important research target and essential oils (EO) from aromatic plants with antimicrobial properties are well documented. However, their uses are limited, and the mechanisms ... -
Prolonged fasting followed by refeeding modifies proteome profile and parvalbumin expression in the fast-twitch muscle of pacu (Piaractus mesopotamicus)
Da Silva-Gomes, Rafaela Nunes; Kuniyoshi, Maria Laura Gabriel ; Da Silva Duran, Bruno Oliveira ; Zanella, Bruna Tereza Thomazini ; Freire, Paula Paccielli ; De Paula, Tassiana Gutierrez ; De Almeida Fantinatti, Bruno Evaristo ; ; Carvalho, Robson Francisco ; Santos, Lucilene Delazari et al. (PLoS ONE, 2019) [Artigo]
Here, we analyzed the fast-twitch muscle of juvenile Piaractus mesopotamicus (pacu) submitted to prolonged fasting (30d) and refeeding (6h, 24h, 48h and 30d). We measured the relative rate of weight and length increase ... -
P-MAPA and IL-12 Differentially Regulate Proteins Associated with Ovarian Cancer Progression: A Proteomic Study
; ; ; Dos Santos, Lucilene Delazari; ; ; ; ; ; (ACS Omega, 2019) [Artigo]
To investigate the potential role of immunotherapies in the cellular and molecular mechanisms associated with ovarian cancer (OC), we applied a comparative proteomic toll using protein identification combined with mass ... -
Anabolism, catabolism and proteomic analysis in the slow-twitch muscle of pacu (Piaractus mesopotamicus) submitted to prolonged fasting followed by refeeding
Gabriel Kuniyoshi, Maria Laura; Nunes da Silva-Gomes, Rafaela ; Thomazini Zanella, Bruna Tereza ; Delazari dos Santos, Lucilene ; Dal-Pai-Silva, Maeli (Aquaculture Research, 2020) [Artigo]
Here, we aimed to study the slow muscle of the fish Piaractus mesopotamicus submitted to 30 days of fasting (D30) followed by 1 day (D31) or 30 days of refeeding (D60). Histological analysis of fibre diameter was performed ... -
Landscape of heart proteome changes in a diet-induced obesity model
Vileigas, Danielle F.; ; Freire, Paula P. ; Marciano, Cecília L. C. ; Sant’Ana, Paula G. ; de Souza, Sérgio L. B. ; Mota, Gustavo A. F. ; da Silva, Vitor L. ; Campos, Dijon H. S. ; Padovani, Carlos R. et al. (Scientific Reports, 2019) [Artigo]
Obesity is a pandemic associated with a high incidence of cardiovascular disease; however, the mechanisms are not fully elucidated. Proteomics may provide a more in-depth understanding of the pathophysiological mechanisms ... -
Unique heterologous fibrin biopolymer with hemostatic, adhesive, sealant, scaffold and drug delivery properties: A systematic review
; Cassaro, Claudia Vilalva; ; ; ; ; ; Ferreira, Rui Seabra ; Barraviera, Benedito ; (Journal of Venomous Animals and Toxins Including Tropical Diseases, 2019) [Resenha]
Fibrin biopolymers, previously referred as fibrin glue or fibrin sealants, are natural biomaterials with diverse applications on health. They have hemostatic, adhesive, sealant, scaffold and drug delivery properties and ... -
Fibrin biopolymer as scaffold candidate to treat bone defects in rats
Cassaro, Claudia Vilalva; Justulin, Luis Antonio ; De Lima, Patrícia Rodrigues ; De Assis Golim, Marjorie ; Biscola, Natália Perussi ; ; ; Doiche, Danuta Pulz ; Pereira, Elenize Jamas ; Ferreira, Rui Seabra et al. (Journal of Venomous Animals and Toxins Including Tropical Diseases, 2019) [Artigo]
Background: Bone tissue repair remains a challenge in tissue engineering. Currently, new materials are being applied and often integrated with live cells and biological scaffolds. The fibrin biopolymer (FBP) proposed in ... -
ANTIAPILIC SERUM ANTAGONIZES TOXICITY INDUCED BY BEE VENOM (APIS MELLIFERA) AND ITS MAJOR COMPONENT, MELITTIN
; ; ; ; Barraviera, Benedito; ; (Toxicon, 2019) [Resumo]
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OPHIDIAN PARAMYXOVIRUS: A SERUM EPIDEMIOLOGICAL STUDY IN CAPTIVE SNAKES
De Oliveira, Cristiano Correa; Melo, Leonardo ; Ullmann, Leila ; Malossi, Camila ; Ferreira, Rui Seabra ; Barraviera, Benedito ; Araujo, Joao Pessoa ; Dos Santos, Lucilene Delazari (Toxicon, 2019) [Resumo]
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OCCUPATIONAL ALLERGY IN THE HANDLING OF SNAKES FROM THE CENTER FOR STUDIES OF VENOM AND VENOMOUS ANIMALS CEVAP/UNESP
Vieira Cavassan, Nayara Rodrigues; De Pontes, Leticia Gomes ; De Oliveira, Laudiceia Alves ; ; ; ; ; Barraviera, Benedito ; Ferreira Junior, Rui Seabra ; et al. (Toxicon, 2019) [Resumo]