Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP) - Botucatu
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Recent Submissions
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Apilic antivenom, a new treatment for bee attacks, is effective in preclinical studies
(Toxicon : official journal of the International Society on Toxinology, 2020) [Artigo] -
Physical-chemical characterization of carbon nanotubes-hydroxyapatite nanocomposites with fibrin sealant derived from snake venom
(Toxicon : official journal of the International Society on Toxinology, 2020) [Artigo] -
Clinical and Therapeutic Aspects of Brazilian Native Bothrops Envenomation in Nine Horses
(Journal of Equine Veterinary Science, 2020) [Artigo]In this retrospective study, clinical records of nine horses with a diagnosis of Bothrops envenomation were investigated. The accidents were classified as severe (5/9), moderate (2/9), or mild (2/9) according to the adapted ... -
Neuroprotection and immunomodulation by dimethyl fumarate and a heterologous fibrin biopolymer after ventral root avulsion and reimplantation
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2020) [Artigo]Background: Ventral root avulsion (VRA) is an experimental approach in which there is an abrupt separation of the motor roots from the surface of the spinal cord. As a result, most of the axotomized motoneurons degenerate ... -
Proteomic analyses unraveling water stress response in two Eucalyptus species originating from contrasting environments for aridity
(Molecular Biology Reports, 2020) [Artigo]Eucalyptus are widely cultivated in several regions of the world due to their adaptability to different climatic conditions and amenable to tree breeding programs. With changes in environmental conditions pointing to an ... -
Metalloproteomic Strategies for Identifying Proteins as Biomarkers of Mercury Exposure in Serrasalmus rhombeus from the Amazon Region
(Biological Trace Element Research, 2020) [Artigo]This manuscript describes the results of a metalloproteomic study of mercury in samples of muscle and liver tissue of the species Serrasalmus rhombeus, popularly known as black piranha and characterised as the most voracious ... -
Glutaredoxin-like protein (GLP)—a novel bacteria sulfurtransferase that protects cells against cyanide and oxidative stresses
(Applied Microbiology and Biotechnology, 2020) [Artigo]The pathogen Xylella fastidiosa belongs to the Xanthomonadaceae family, a large group of Gram-negative bacteria that cause diseases in many economically important crops. A predicted gene, annotated as glutaredoxin-like ... -
Improved production of the recombinant phospholipase A1 from Polybia paulista wasp venom expressed in bacterial cells for use in routine diagnostics
(3 Biotech, 2020) [Artigo]Phospholipase A1 (PLA1) is one of the three major allergens identified in the venom of P. paulista (Hymenoptera: Vespidae), a clinically relevant wasp from southeastern Brazil. The recombinant form of this allergen (rPoly ... -
Photobiomodulation therapy associated with heterologous fibrin biopolymer and bovine bone matrix helps to reconstruct long bones
(Biomolecules, 2020) [Artigo]Bone defects cause aesthetic and functional changes that affect the social, economic and especially the emotional life of human beings. This complication stimulates the scientific community to investigate strategies aimed ... -
Epididymal protease inhibitor (EPPIN) is a protein hub for seminal vesicle-secreted protein SVS2 binding in mouse spermatozoa
(Molecular and Cellular Endocrinology, 2020) [Artigo]EPPIN is a sperm-surface drug target for male contraception. Here we investigated EPPIN-interacting proteins in mouse spermatozoa. We showed that EPPIN is an androgen-dependent gene, expressed in the testis and epididymis, ... -
Proteomic analysis and antibacterial resistance mechanisms of Salmonella Enteritidis submitted to the inhibitory effect of Origanum vulgare essential oil, thymol and carvacrol
(Journal of Proteomics, 2020) [Artigo]Biological properties of natural products are an important research target and essential oils (EO) from aromatic plants with antimicrobial properties are well documented. However, their uses are limited, and the mechanisms ... -
Prolonged fasting followed by refeeding modifies proteome profile and parvalbumin expression in the fast-twitch muscle of pacu (Piaractus mesopotamicus)
(PLoS ONE, 2019) [Artigo]Here, we analyzed the fast-twitch muscle of juvenile Piaractus mesopotamicus (pacu) submitted to prolonged fasting (30d) and refeeding (6h, 24h, 48h and 30d). We measured the relative rate of weight and length increase ... -
P-MAPA and IL-12 Differentially Regulate Proteins Associated with Ovarian Cancer Progression: A Proteomic Study
(ACS Omega, 2019) [Artigo]To investigate the potential role of immunotherapies in the cellular and molecular mechanisms associated with ovarian cancer (OC), we applied a comparative proteomic toll using protein identification combined with mass ... -
Anabolism, catabolism and proteomic analysis in the slow-twitch muscle of pacu (Piaractus mesopotamicus) submitted to prolonged fasting followed by refeeding
(Aquaculture Research, 2020) [Artigo]Here, we aimed to study the slow muscle of the fish Piaractus mesopotamicus submitted to 30 days of fasting (D30) followed by 1 day (D31) or 30 days of refeeding (D60). Histological analysis of fibre diameter was performed ... -
Landscape of heart proteome changes in a diet-induced obesity model
(Scientific Reports, 2019) [Artigo]Obesity is a pandemic associated with a high incidence of cardiovascular disease; however, the mechanisms are not fully elucidated. Proteomics may provide a more in-depth understanding of the pathophysiological mechanisms ... -
Unique heterologous fibrin biopolymer with hemostatic, adhesive, sealant, scaffold and drug delivery properties: A systematic review
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2019) [Resenha]Fibrin biopolymers, previously referred as fibrin glue or fibrin sealants, are natural biomaterials with diverse applications on health. They have hemostatic, adhesive, sealant, scaffold and drug delivery properties and ... -
Fibrin biopolymer as scaffold candidate to treat bone defects in rats
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2019) [Artigo]Background: Bone tissue repair remains a challenge in tissue engineering. Currently, new materials are being applied and often integrated with live cells and biological scaffolds. The fibrin biopolymer (FBP) proposed in ... -
OPHIDIAN PARAMYXOVIRUS: A SERUM EPIDEMIOLOGICAL STUDY IN CAPTIVE SNAKES
(Toxicon, 2019) [Resumo]