Recent Submissions

  • Isolation and Functional Characterization of an Acidic Myotoxic Phospholipase A₂ from Colombian Bothrops asper Venom

    Posada Arias, Silvia; Rey-Suárez, Paola; Pereáñez J, Andrés; Acosta, Cristian; Rojas, Mauricio; Delazari Dos Santos, Lucilene; Ferreira, Rui Seabra; Núñez, Vitelbina (Toxins, 2017) [Artigo]
    Myotoxic phospholipases A₂ (PLA₂) are responsible for many clinical manifestations in envenomation by Bothrops snakes. A new myotoxic acidic Asp49 PLA₂ (BaCol PLA₂) was isolated from Colombian Bothrops asper venom using ...
  • Long-Standing Motor and Sensory Recovery following Acute Fibrin Sealant Based Neonatal Sciatic Nerve Repair

    Perussi Biscola, Natalia; Politti Cartarozzi, Luciana; Ferreira Junior, Rui Seabra; Barraviera, Benedito; Leite Rodrigues de Oliveira, Alexandre (Neural plasticity, 2016) [Artigo]
    Brachial plexus lesion results in loss of motor and sensory function, being more harmful in the neonate. Therefore, this study evaluated neuroprotection and regeneration after neonatal peripheral nerve coaptation with ...
  • Reviewer acknowledgement 2015

    Barraviera, Benedito (Journal of Venomous Animals and Toxins Including Tropical Diseases, 2016) [Artigo]
    The Editor of Journal of Venomous Animals and Toxins including Tropical Diseases would like to thank all of our reviewers, both external and Editorial Board Members, who have contributed to the journal in Volume 21 (2015) ...
  • BjSP, a novel serine protease from Bothrops jararaca snake venom that degrades fibrinogen without forming fibrin clots

    Carone, Sante E.I.; Menaldo, Danilo L.; Sartim, Marco A.; Bernardes, Carolina P.; Caetano, Renato C.; da Silva, Ronivaldo R. Autor UNESP; Cabral, Hamilton; Barraviera, Benedito Autor UNESP; Ferreira Junior, Rui S. Autor UNESP; Sampaio, Suely V. (Toxicology and Applied Pharmacology, 2018) [Artigo]
    Snake venom serine proteases (SVSPs) are commonly described as capable of affecting hemostasis by interacting with several coagulation system components. In this study, we describe the isolation and characterization of ...
  • Serological proteomic biomarkers to identify Paracoccidioides species and risk of relapse

    Sylvestre, Tatiane Fernanda Autor UNESP; Cavalcante, Ricardo de Souza Autor UNESP; Da Silva, Julhiany de Fátima Autor UNESP; Miranda Paniago, Anamaria Mello; Weber, Simone Schneider; Pauletti, Bianca Alves; Carvalho, Lídia Raquel de Autor UNESP; Dos Santos, Lucilene Delazari Autor UNESP; Mendes, Rinaldo Poncio Autor UNESP (PLoS ONE, 2018) [Artigo]
    The sensitivity of the double agar gel immunodiffusion test is about 90% in patients with untreated paracoccidioidomycosis (PCM), but it is much lower in cases of relapse. In addition, serum from patients with PCM caused ...
  • Neuroprotection and immunomodulation following intraspinal axotomy of motoneurons by treatment with adult mesenchymal stem cells

    Spejo, A. B.; Chiarotto, G. B.; Ferreira, A. D.F.; Gomes, D. A.; Ferreira, R. S. Autor UNESP; Barraviera, B. Autor UNESP; Oliveira, A. L.R. (Journal of Neuroinflammation, 2018) [Artigo]
    Background: Treatment of spinal cord injury is dependent on neuronal survival, appropriate synaptic circuit preservation, and inflammatory environment management. In this sense, mesenchymal stem cell (MSC) therapy is a ...
  • Current advances in immunological studies on the vespidae venom antigen 5: Therapeutic and prophylaxis to hypersensitivity responses

    Bazon, Murilo Luiz Autor UNESP; Silveira, Lais Helena Autor UNESP; Simioni, Patricia Ucelli; Brochetto-Braga, Márcia Regina Autor UNESP (Toxins, 2018) [Resenha]
    Although systemic reactions caused by allergenic proteins present in venoms affect a small part of the world population, Hymenoptera stings are among the main causes of immediate hypersensitivity responses, with risk of ...
  • Toxicity and motor changes in africanized honey bees (Apis mellifera l.) exposed to fipronil and imidacloprid

    Bovi, Thaís S. Autor UNESP; Zaluski, Rodrigo Autor UNESP; Orsi, Ricardo de Oliveira Autor UNESP (Anais da Academia Brasileira de Ciencias, 2018) [Artigo]
    This study evaluated the in vitro toxicity and motor activity changes in African-derived adult honey bees (Apis mellifera L.) exposed to lethal or sublethal doses of the insecticides fipronil and imidacloprid. Mortality ...
  • Combination of heterologous fibrin sealant and bioengineered human embryonic stem cells to improve regeneration following autogenous sciatic nerve grafting repair

    Mozafari, Roghayeh; Kyrylenko, Sergiy; Castro, Mateus Vidigal; Ferreira, Rui Seabra Autor UNESP; Barraviera, Benedito Autor UNESP; Oliveira, Alexandre Leite Rodrigues (Journal of Venomous Animals and Toxins Including Tropical Diseases, 2018) [Artigo]
    Background: Peripheral nerve injury is a worldwide clinical problem, and the preferred surgical method for treating it is the end-to-end neurorrhaphy. When it is not possible due to a large nerve gap, autologous nerve ...
  • Molecular identification and phylogenetic analysis of Bothrops insularis bacterial and fungal microbiota

    Barbosa, Lidiane Nunes Autor UNESP; Ferreira, Rui Seabra Autor UNESP; Luiza Mello, Priscila Autor UNESP; Garcia Garces, Hans Autor UNESP; Luana Chechi, Jéssica Autor UNESP; Frachin, Tarsila Autor UNESP; De Barros, Luciana Curtolo Autor UNESP; De Moraes Guimenes Bosco, Sandra Autor UNESP; Bagagli, Eduardo Autor UNESP; Fernandes Júnior, Ary Autor UNESP et al. (Journal of Toxicology and Environmental Health - Part A: Current Issues, 2018) [Artigo]
    Bothrops insularis, known as the golden lancehead snake, has its natural habitat restricted to Queimada Grande Island on the southern coast of Brazil. This culture-dependent study aimed to identify microorganisms obtained ...
  • Crotalus durissus terrificus crotapotin naturally displays preferred positions for amino acid substitutions

    de Oliveira, Laudicéia Alves Autor UNESP; Ferreira, Rui Seabra Autor UNESP; Barraviera, Benedito Autor UNESP; de Carvalho, Francilene Capel Tavares Autor UNESP; de Barros, Luciana Curtolo Autor UNESP; dos Santos, Lucilene Delazari Autor UNESP; Pimenta, Daniel Carvalho Autor UNESP (Journal of Venomous Animals and Toxins Including Tropical Diseases, 2017) [Artigo]
    Background: Classically, Crotalus durissus terrificus (Cdt) venom can be described, according to chromatographic criteria, as a simple venom, composed of four major toxins, namely: gyroxin, crotamine, crotoxin and convulxin. ...
  • Phospholipase A1-based cross-reactivity among venoms of clinically relevant Hymenoptera from Neotropical and temperate regions

    Perez-Riverol, Amilcar Autor UNESP; Fernandes, Luís Gustavo Romani; Musacchio Lasa, Alexis; dos Santos-Pinto, José Roberto Aparecido Autor UNESP; Moitinho Abram, Débora; Izuka Moraes, Gabriel Hideki Autor UNESP; Jabs, Frederic; Miehe, Michaela; Seismman, Henning; Palma, Mario Sergio Autor UNESP et al. (Molecular Immunology, 2018) [Artigo]
    Molecular cross-reactivity caused by allergen homology or cross-reactive carbohydrate determinants (CCDs) is a major challenge for diagnosis and immunotherapy of insect venom allergy. Venom phospholipases A1 (PLA1s) are ...
  • Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies

    Gagete, Elaine; Delazari Dos Santos, Lucilene Autor UNESP; Gomes De Pontes, Leticia Autor UNESP; Morato Castro, Fábio (World Allergy Organization Journal, 2017) [Artigo]
    Background: The incidence of anaphylaxis is increasing in several parts of the world; thus, determining the prevalence of the disease in a given region is important to understand the factors involved and to promote measures ...
  • Isolation and functional characterization of an acidic myotoxic phospholipase A2 from colombian Bothrops asper venom

    Arias, Silvia Posada; Rey-Suárez, Paola; Pereáñez J, Andrés; Acosta, Cristian; Rojas, Mauricio; dos Santos, Lucilene Delazari Autor UNESP; Ferreira, Rui Seabra Autor UNESP; Núñez, Vitelbina (Toxins, 2017) [Artigo]
    Myotoxic phospholipases A2 (PLA2) are responsible for many clinical manifestations in envenomation by Bothrops snakes. A new myotoxic acidic Asp49 PLA2 (BaCol PLA2) was isolated from Colombian Bothrops asper venom using ...
  • A unique heterologous fibrin sealant (HFS) as a candidate biological scaffold for mesenchymal stem cells in osteoporotic rats

    Orsi, Patrícia Rodrigues Autor UNESP; Landim-Alvarenga, Fernanda Cruz Autor UNESP; Justulin, Luis Antônio Autor UNESP; Kaneno, Ramon Autor UNESP; De Assis Golim, Marjorie Autor UNESP; Dos Santos, Daniela Carvalho Autor UNESP; Creste, Camila Fernanda Zorzella Autor UNESP; Oba, Eunice Autor UNESP; Maia, Leandro Autor UNESP; Barraviera, Benedito Autor UNESP et al. (Stem Cell Research and Therapy, 2017) [Artigo]
    Background: The injection of mesenchymal stem cells (MSCs) directly into the bone of osteoporotic (OP) patients for rapid recovery has been studied worldwide. Scaffolds associated with MSCs are used to maintain and avoid ...
  • Heterologous expression, purification and immunoreactivity of the antigen 5 from polybia paulista wasp venom

    Bazon, Murilo Luiz Autor UNESP; Perez-Riverol, Amilcar Autor UNESP; Dos Santos-Pinto, José Roberto Aparecido Autor UNESP; Fernandes, Luis Gustavo Romani; Lasa, Alexis Musacchio; Justo-Jacomini, Débora Laís Autor UNESP; Palma, Mario Sergio Autor UNESP; De Lima Zollner, Ricardo; Brochetto-Braga, Márcia Regina Autor UNESP (Toxins, 2017) [Artigo]
    Polybia paulista (Hymenoptera: Vespidae) is responsible for a high number of sting accidents and anaphylaxis events in Southeast Brazil, Argentina and Paraguay. The specific detection of allergy to the venom of this wasp ...
  • Stimulation of morphofunctional repair of the facial nerve with photobiomodulation, using the end-to-side technique or a new heterologous fibrin sealant

    Rosso, Marcelie Priscila de Oliveira; Rosa Júnior, Geraldo Marco; Buchaim, Daniela Vieira; German, Iris Jasmin Santos; Pomini, Karina Torres; de Souza, Rafael Gomes; Pereira, Mizael; Favaretto Júnior, Idvaldo Aparecido; Bueno, Cleuber Rodrigo de Souza; Gonçalves, Jéssica Barbosa de Oliveira et al. (Journal of Photochemistry and Photobiology B: Biology, 2017) [Artigo]
    This research evaluated the influence of Photobiomodulation Therapy (PBMT) on lesions of the facial nerve repaired with the end-to-side technique or coaptation with a new heterologous fibrin sealant. Thirty-two Wistar rats ...
  • Efficacy of Laser Photobiomodulation on Morphological and Functional Repair of the Facial Nerve

    Buchaim, Daniela Vieira; Andreo, Jesus Carlos; Ferreira Junior, Rui Seabra Autor UNESP; Barraviera, Benedito Autor UNESP; De Castro Rodrigues, Antonio; De Cássia MacEdo, Mariana; Rosa Junior, Geraldo Marco; Shinohara, Andre Luis; German, Iris Jasmin Santos; Pomini, Karina Torres et al. (Photomedicine and Laser Surgery, 2017) [Artigo]
    Objective: Evaluate the efficacy of low-level laser therapy (LLLT) on qualitative, quantitative, and functional aspects in the facial nerve regeneration process. Materials and methods: Forty-two male Wistar rats were used, ...
  • Plasma proteome of buffaloes

    de Pontes, Leticia Gomes Autor UNESP; Cavassan, Nayara Rodrigues Vieira Autor UNESP; de Barros, Luciana Curtolo Autor UNESP; Ferreira Junior, Rui Seabra Autor UNESP; Barraviera, Benedito Autor UNESP; Santos, Lucilene Delazari dos Autor UNESP (Proteomics - Clinical Applications, 2017) [Artigo]
    The proteomic approach has aroused the interest of veterinary medicine researchers, especially regarding the production of biopharmaceuticals and diagnosis of diseases in farm animals. Water buffaloes have gained prominence ...
  • Wasp venomic: Unravelling the toxins arsenal of Polybia paulista venom and its potential pharmaceutical applications

    Perez-Riverol, Amilcar Autor UNESP; dos Santos-Pinto, José Roberto Aparecido Autor UNESP; Lasa, Alexis Musacchio; Palma, Mario Sergio Autor UNESP; Brochetto-Braga, Márcia Regina Autor UNESP (Journal of Proteomics, 2017) [Resenha]
    Polybia paulista (Hymenoptera: Vespidae) is a neotropical social wasp from southeast Brazil. As most social Hymenoptera, venom from P. paulista comprises a complex mixture of bioactive toxins ranging from low molecular ...

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