RSS 1.0Centro de Microscopia Eletrônica (CME) - Botucatu
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Telocytes are associated with tissue remodeling and angiogenesis during the postlactational involution of the mammary gland in gerbils
; Leonel, Ellen C. R.
; ; ; Barquilha, Caroline N. ; Felisbino, Sérgio L. ; Goés, Rejane M. ; Vilamaior, Patricia S. L. ; Taboga, Sebastião R. (Cell Biology International, 2020) [Artigo]
The postlactational involution of the mammary gland is a complex process. It involves the collapse of the alveoli and the remodeling of the extracellular matrix, which in turn implies a complex set of interrelations between ... -
Explant culture: A relevant tool for the study of telocytes
; ; ; Da Silva, Alana D. T.; Lima, Maria L. D. ; Rahal, Paula ; Góes, Rejane M. ; Taboga, Sebastião R. ; (Cell Biology International, 2020) [Artigo]
Telocytes are cells present in the stroma of various tissues including the prostate. The detection of telocytes is still very much dependent on obtaining ultrastructural data that show the presence of telopodes, which are ... -
Parasite × vector relationship in Chagas disease: does Trypanosoma cruzi (Chagas, 1909) infection affect the spermatogenesis of Triatoma infestans (Klug, 1834)?
de Oliveira, Ana Beatriz Bortolozo; Tedeschi, Bianca Barbério Bogdan ; de Oliveira, Jader ; Madeira, Fernanda Fernandez ; Falleiros Junior, Luiz Roberto ; Silva Junior, Fernando César ; da Rosa, João Aristeu ; de Azeredo-Oliveira, Maria Tercília Vilela ; Alevi, Kaio Cesar Chaboli (Parasitology Research, 2020) [Artigo]
The parasite-vector interaction of Chagas disease is still poorly understood and the understanding of this relationship can help in the development of new strategies to control Trypanosoma cruzi transmission, which is the ... -
Aluminum exposure promotes histopathological and pro-oxidant damage to the prostate and gonads of male and female adult gerbils
; ; ; ; ; ; Taboga, Sebastião Roberto; ; ; (Experimental and Molecular Pathology, 2020) [Artigo]
Since the industrial revolution, all living beings have become susceptible to numerous sources of aluminum (Al) exposure. In addition to causing proven toxicity in many organs and systems, Al can also have estrogenic ... -
Neonatal exposure to aluminum chloride disrupts branching morphogenesis and hormonal signaling of the ventral male prostate and female prostate of gerbils
; ; ; ; ; ; ; Taboga, Sebastião Roberto; ; (Journal of Trace Elements in Medicine and Biology, 2020) [Artigo]
Backgroung: Exposure to environmental pollutants in critical developmental windows may predispose the prostate to permanent changes in its homeostasis. Thus, it is essential to know the effects that environmental toxics, ... -
Blocking drug-induced autophagy with chloroquine in HCT-116 colon cancer cells enhances DC maturation and T cell responses induced by tumor cell lysate
Zamame Ramirez, Jofer Andree; Romagnoli, Graziela Gorete ; Falasco, Bianca Francisco ; Gorgulho, Carolina Mendonça ; Sanzochi Fogolin, Carla ; dos Santos, Daniela Carvalho ; Junior, João Pessoa Araújo ; ; ; Kaneno, Ramon (International Immunopharmacology, 2020) [Artigo]
Autophagy is an important mechanism for tumor escape, allowing tumor cells to recover from the damage induced by chemotherapy, radiation therapy, and immunotherapy and contributing to the development of resistance. The ... -
Postnatal exposure to finasteride causes different effects on the prostate of male and female gerbils
; ; Santos, Vitória A.; Cabral, Ágata S. ; Lima, Maria L. D. ; Bedolo, Carolina M. ; Calmon, Marília F. ; Rahal, Paula ; Góes, Rejane M. ; Vilamaior, Patricia S. L. et al. (Cell Biology International, 2020) [Artigo]
The development and maintenance of prostate function depend on a fine balance between oestrogen and androgen levels. Finasteride inhibits 5α-reductase, which is responsible for the conversion of testosterone into its most ... -
Anatomical and ultrastructural studies on gelatinous fibers in the organs of non-woody xerophytic and hydrophytic species
Piva, Tayeme Cristina; Machado, Silvia Rodrigues ; (Botany, 2019) [Artigo]
Gelatinous fibers (G-layer) occur widely in various organs and plant tissues of both primary and secondary origin, but they are best known in tension wood. Here, we describe the occurrence, distribution patterns, and ... -
Novaluron impairs the silk gland and productive performance of silkworm Bombyx mori (Lepidoptera: Bombycidae) larvae
Santorum, Marilucia; ; ; Carvalho dos Santos, Daniela (Chemosphere, 2020) [Artigo]
This study investigates the effects of the insect growth regulator Novaluron on the silk gland (SG) and silk cocoon production in a nontarget insect, the silkworm Bombyx mori, which is a model research insect among Lepidoptera ... -
Low-dose in utero exposure to finasteride promotes developmental changes in both male and female gerbil prostates
; ; Santos, Vitória A.; Amaro, Gustavo M. ; Calmon, Marília F. ; Rahal, Paula ; Góes, Rejane M. ; Vilamaior, Patricia S. L. ; Taboga, Sebastião R. (Environmental Toxicology, 2019) [Artigo]
The prostate is an accessory reproductive gland that is sensitive to the action of exogenous compounds known as endocrine disrupters that alter normal hormonal function. Finasteride is a widely used chemical that acts to ... -
Differences between male and female prostates in terms of physiology, sensitivity to chemicals and pathogenesis—A review in a rodent model
Sanches, Bruno D. A.; Carvalho, Hernandes F. ; Maldarine, Juliana S. ; Biancardi, Manoel F. ; Santos, Fernanda C. A. ; Vilamaior, Patricia S. L. ; Taboga, Sebastião R. (Cell Biology International, 2019) [Resenha]
The prostate is a gland that is not exclusively present in males, being also found in females of several mammalian species, including humans. There is evidence that the prostate in both sexes is affected by the same ... -
Prenatal exposure to finasteride promotes sex-specific changes in gerbil prostate development
; ; Cabral, Ágata S.; Lima, Maria L. D. ; Guerra, Luiz H. A. ; Baraldi, Carolina M. B. ; Calmon, Marília F. ; Rahal, Paula ; Góes, Rejane M. ; Vilamaior, Patricia S. L. et al. (Reproduction, Fertility and Development, 2019) [Artigo]
Finasteride is a drug that is widely used in the treatment of benign prostatic hyperplasia, hair loss and even as a chemotherapeutic agent in the treatment of prostatic adenocarcinoma. However, its use is known to cause ... -
The comet assay in Ceraeochrysa claveri (Neuroptera: Chrysopidae): A suitable approach for detecting somatic and germ cell genotoxicity induced by agrochemicals
Gastelbondo-Pastrana, Bertha Irina; Fernandes, Fábio Henrique ; Salvadori, Daisy Maria Fávero ; Santos, Daniela Carvalho dos (Chemosphere, 2019) [Artigo]
Some agrochemicals are genotoxic to several organisms. Nevertheless, few protocols are currently available for measuring the toxicogenetic effects of these compounds in target and non-target field-collected species of ... -
Short-term exposure to chrysin promotes proliferative responses in the ventral male prostate and female prostate of adult gerbils
Campos, Mônica S.; ; ; Regasini, Luis O. ; ; ; Taboga, Sebastião R. ; (International Journal of Experimental Pathology, 2019) [Artigo]
Chrysin (5,7-dihydroxyflavone) is a bioactive compound found in different fruits, vegetables, honey and propolis. This flavone has been suggested for the treatment of reproductive dysfunction, mainly because of its antioxidant ... -
Characterisation and origins of melanin-concentrating hormone immunoreactive fibres of the posterior lobe of the pituitary and median eminence during lactation in the Long-Evans rat
; ; ; ; ; ; ; de-Moraes Machado, Carla; Horta-Júnior, José A. C. ; (Journal of Neuroendocrinology, 2019) [Artigo]
Although the melanin-concentrating hormone (MCH) and its coding mRNA are predominantly found in the tuberal hypothalamus, there is detectable synthesis of MCH in the preoptic hypothalamus exclusively in lactating dams, ... -
Glycoprotein hormone receptor knockdown leads to reduced reproductive success in male Aedes aegypti
; Garcia, Ana S.G.; Scudeler, Elton L. ; Dos Santos, Daniela C. ; Nóbrega, Rafael H. ; (Frontiers in Physiology, 2019) [Artigo]
Glycoprotein hormone receptors mediate a diverse range of physiological functions in vertebrate and invertebrate organisms. The heterodimeric glycoprotein hormone GPA2/GPB5 and its receptor LGR1, constitute a recently ... -
Autophagy and vacuolar biogenesis during the nectary development
Machado, Silvia R.; Rodrigues, Tatiane M. (Planta, 2019) [Artigo]
Main conclusion: Different autophagy pathways are a driver of vacuolar biogenesis and are development stage specific during the extrafloral nectary development in Citharexylum myrianthum. Abstract: Plant autophagy plays ... -
Cobalt-chromium-enriched medium ameliorates shear-stressed endothelial cell performance
Machado, Mariana Issler Pinheiro; Gomes, Anderson Moreira ; Rodrigues, Marcel Ferreira ; Silva Pinto, Thais ; da Costa Fernandes, Célio Júnior ; Bezerra, Fábio J. ; Zambuzzi, Willian Fernando (Journal of Trace Elements in Medicine and Biology, 2019) [Artigo]
Angiogenesis is a relevant mechanism to be considered for the success of bone healing, even considering endosseous implantable devices, providing adequate delivery of substances necessaries for the cell viability and bone ... -
Differential inflammatory landscape stimulus during titanium surfaces obtained osteogenic phenotype
da S. Feltran, Georgia; Bezerra, Fábio ; da Costa Fernandes, Célio Júnior ; Ferreira, Marcel Rodrigues ; Zambuzzi, Willian F. (Journal of Biomedical Materials Research - Part A, 2019) [Artigo]
Molecular mechanism governing inflammatory scenario in response to titanium (Ti)-nanotexturing surfaces needs to be better addressed. Thus, we subjected pre-osteoblast to different Ti-texturing surfaces, as follows: machined ... -
Negative impact of Novaluron on the nontarget insect Bombyx mori (Lepidoptera: Bombycidae)
Santorum, Marilucia; ; ; Padovani, Carlos Roberto ; ; dos Santos, Daniela Carvalho (Environmental Pollution, 2019) [Artigo]
Due to increased use of agrochemicals and growing concerns about ecotoxicology, the development of new insecticides, moving away from those with neurotoxic and broad spectrum effects towards insecticides that are safer for ...