Nanostructured Hydrogels

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dc.contributor.authorMontoro, Sérgio Roberto [UNESP]
dc.contributor.authorMedeiros, Simone de Fátima
dc.contributor.authorAlves, Gizelda Maria
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-29T07:17:22Z
dc.date.available2022-04-29T07:17:22Z
dc.date.issued2013-01-01
dc.description.abstractPolymer systems can be developed into a variety of functional forms to meet industrial and scientific applications. In general, they are presented in four common physical forms: (1) linear free chains in solution, (2) covalently or physically cross-linked reversible gels, (3) micro and nanoparticles, and (4) chains adsorbed or in surface-grafted form. Hydrogels are polymeric particles consisting of water-soluble polymer chains, chemically or physically connected using, in general, a cross-linking agent. These materials do not dissolve in water but may swell considerably in aqueous medium, demonstrating an extraordinary ability (>20%) to absorb water into the reticulated structure. Such features make these materials promising tools in the biomedical field, especially as controlled drug release systems. This chapter describes recent progress in the development and applications of polymeric nanostructured hydrogels, mainly in the context of biomedical devices. Additionally, it reports the significant advances in synthesis and characterization strategies of these materials. Special attention is devoted to smart or stimuli-responsive bionanogels, which mimic the property of living systems responding to environmental changes such as pH, temperature, light, pressure, electric field, chemicals, or ionic strength, or a combination of different stimuli. Consequently, these bionanogels offer an efficient solution to various biomedical limitations in the field of drug administration. © 2014 Elsevier Inc. All rights reserved.en
dc.description.affiliationLaboratory of Polymers Chemical Engineering Department Engineering School of Lorena University of São Paulo, São Paulo
dc.description.affiliationFatigue and Aeronautic Materials Research Group Materials and Technology Department UNESP-Universidade Estadual Paulista, Guaratinguetá
dc.description.affiliationUnespFatigue and Aeronautic Materials Research Group Materials and Technology Department UNESP-Universidade Estadual Paulista, Guaratinguetá
dc.format.extent325-355
dc.identifierhttp://dx.doi.org/10.1016/B978-1-4557-3159-6.00010-9
dc.identifier.citationNanostructured Polymer Blends, p. 325-355.
dc.identifier.doi10.1016/B978-1-4557-3159-6.00010-9
dc.identifier.scopus2-s2.0-84903659249
dc.identifier.urihttp://hdl.handle.net/11449/227786
dc.language.isoeng
dc.relation.ispartofNanostructured Polymer Blends
dc.sourceScopus
dc.subjectBiomedical
dc.subjectBionanogels
dc.subjectCross-linking agents
dc.subjectHydrogels
dc.subjectNanostructured hydrogels
dc.subjectPolymer colloids
dc.subjectPolymer systems
dc.subjectPolymeric gels
dc.titleNanostructured Hydrogelsen
dc.typeCapítulo de livro
unesp.departmentMateriais e Tecnologia - FEGpt

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Guaratinguetá - FEG - Faculdade de Engenharia e Ciências