High-performance liquid chromatographic quantification of flavonoids in Eriocaulaceae species and their antimicrobial activity

dc.contributor.authorDa Silva, Marcelo Aparecido [UNESP]
dc.contributor.authorCardoso, Claudia Andréa Lima
dc.contributor.authorVilegas, Wagner [UNESP]
dc.contributor.authorDos Santos, Lourdes Campaner [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade Estadual de Mato Grosso do Sul (UEMS)
dc.date.accessioned2022-04-28T20:59:05Z
dc.date.available2022-04-28T20:59:05Z
dc.date.issued2009-11-01
dc.description.abstractQuantification of prepared samples by analysis using high performance liquid chromatography with DAD detection was developed to analyze rutin, 6-methoxyapigenin, and 6-methoxyapigenin-7-O-β-D-glucopyranoside isolated from methanolic extracts of different genus: Syngonanthus, Leiothix and Eriocaulon (Eriocaulaceae). The linearity, accuracy, and the inter-day precision of the procedure were evaluated. The calibration curves were linear. The recoveries of the flavonoids in the samples analyzed were 96.3% to 98.5%. The percentage coefficient of variation for the quantitative analysis of the flavonoids in the analyses of the samples was under 5%. The antimicrobial activity of the five methanol extracts of these Eriocaulaceae species was assayed against the microorganisms Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella setubal, Saccharomyces cerevisiae and Candida albicans. Measured MIC values ranged from 1.25 to 10.00 mg/mL. The flavonoid contents suggest that Eriocaulaceae species may be a promising source of compounds to produce natural phytomedicines.en
dc.description.affiliationUNESP-Univ Estadual Paulista Instituto de Química Departamento de Química Orgânica, CP 355, CEP 14800-900, Araraquara, São Paulo
dc.description.affiliationUEMS Course of Chemistry Mato Grosso do Sul State University, CP 351, CEP 79804-970, Dourados, Mato Grosso do Sul
dc.description.affiliationUnespUNESP-Univ Estadual Paulista Instituto de Química Departamento de Química Orgânica, CP 355, CEP 14800-900, Araraquara, São Paulo
dc.format.extent4644-4654
dc.identifierhttp://dx.doi.org/10.3390/molecules14114661
dc.identifier.citationMolecules, v. 14, n. 11, p. 4644-4654, 2009.
dc.identifier.doi10.3390/molecules14114661
dc.identifier.issn1420-3049
dc.identifier.scopus2-s2.0-73349097549
dc.identifier.urihttp://hdl.handle.net/11449/225723
dc.language.isoeng
dc.relation.ispartofMolecules
dc.sourceScopus
dc.subjectEriocaulaceae
dc.subjectFlavonoids
dc.subjectLiquid chromatography
dc.subjectQuantification
dc.titleHigh-performance liquid chromatographic quantification of flavonoids in Eriocaulaceae species and their antimicrobial activityen
dc.typeArtigo
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Química, Araraquarapt
unesp.departmentQuímica Orgânica - IQARpt

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