Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques

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dc.contributor.authorÁlvarez-Román, R.
dc.contributor.authorSilva-Flores, P. G.
dc.contributor.authorGalindo-Rodríguez, S. A.
dc.contributor.authorHuerta-Heredia, A. A.
dc.contributor.authorVilegas, W. [UNESP]
dc.contributor.authorPaniagua-Vega, D.
dc.contributor.institutionUniversidad Autónoma de Nuevo León
dc.contributor.institutionInstituto de Biotecnología. Universidad del Papaloapan
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionCátedras CONACYT-UANL
dc.contributor.institutionCátedras CONACYT-UNPA
dc.date.accessioned2020-12-12T01:48:12Z
dc.date.available2020-12-12T01:48:12Z
dc.date.issued2020-03-01
dc.description.abstractThe phytochemical profile, formulations (nanoparticles and gel), moisturizing and antioxidant potential of a hydroalcoholic fraction of Moringa oleifera leaves (HFM) were determined. These were obtained through the application of eco-friendly strategies of cultivation and processing. The HFM phytochemical analysis by ESI-IT-MSn showed the presence of seven compounds (flavonoids and phenolic acids). The viscosity, pH and particle size of HFM formulations ensure the suitability for topical application. Antioxidant activity was determined by inhibition of lipid peroxidation and ferric thiocyanate in vitro; it was confirmed that HFM and in formulations showed a significant inhibition of oxidation. In relation to the in vitro skin biophysical evaluation for topical formulations of HFM, water content, lipids and trans-epidermal water loss on the skin were favored with the presence of HFM. In addition, skin pH was not been modified. Our results emphasize the moisturizing and antioxidant potential of the moringa-formulation as a new skin drug delivery system.en
dc.description.affiliationDepartamento de Química Analítica Facultad de Medicina Universidad Autónoma de Nuevo León, Av. Fco. I. Madero y Dr. E. Aguirre Pequeño s/n
dc.description.affiliationDepartamento de Química Analítica Facultad de Ciencias Biológicas Universidad Autónoma de Nuevo León, Av. Pedro de Alba s/n
dc.description.affiliationInstituto de Biotecnología. Universidad del Papaloapan, Av. Circuito Central No. 200 Col. Parque Industrial. Tuxtepec
dc.description.affiliationInstituto de Biociências – Câmpus do litoral Paulista UNESP – Universidade Estadual Paulista, Praça Dom Infante Henrique s/n, Parque Bitaru CEP 11330-900, São Vicente
dc.description.affiliationCátedras CONACYT-UANL
dc.description.affiliationCátedras CONACYT-UNPA
dc.description.affiliationUnespInstituto de Biociências – Câmpus do litoral Paulista UNESP – Universidade Estadual Paulista, Praça Dom Infante Henrique s/n, Parque Bitaru CEP 11330-900, São Vicente
dc.description.sponsorshipConsejo Nacional de Ciencia y Tecnología
dc.description.sponsorshipIdConsejo Nacional de Ciencia y Tecnología: -
dc.description.sponsorshipIdConsejo Nacional de Ciencia y Tecnología: 284813
dc.description.sponsorshipIdConsejo Nacional de Ciencia y Tecnología: CB/2016
dc.format.extent404-411
dc.identifierhttp://dx.doi.org/10.1016/j.sajb.2019.10.011
dc.identifier.citationSouth African Journal of Botany, v. 129, p. 404-411.
dc.identifier.doi10.1016/j.sajb.2019.10.011
dc.identifier.issn0254-6299
dc.identifier.scopus2-s2.0-85075871834
dc.identifier.urihttp://hdl.handle.net/11449/199745
dc.language.isoeng
dc.relation.ispartofSouth African Journal of Botany
dc.sourceScopus
dc.subjectESI-IT-MSn
dc.subjectGel
dc.subjectHydroalcoholic extract
dc.subjectMoringa oleífera
dc.subjectNanoparticles
dc.subjectProtected cropping
dc.subjectSkin bioengineering techniques
dc.subjectSPE
dc.titleMoisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniquesen
dc.typeArtigo
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, São Vicentept
unesp.departmentCiências Biológicas - IBCLPpt

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São Vicente - IBCLP - Instituto de Biociências