Topical application of gentamicin or cephalothin in the healing of surgical wounds in dogs

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dc.contributor.authorMinto, Bruno Watanabe [UNESP]
dc.contributor.authorPazzini, Josiane Morais
dc.contributor.authorKawamoto, Fernando Yoiti Kitamura [UNESP]
dc.contributor.authorFranco, Guilherme Galhardo [UNESP]
dc.contributor.authorBorsaro, Camila Portério [UNESP]
dc.contributor.authorZanato, Laura [UNESP]
dc.contributor.authorCastro do Nascimento Hama, Lismara [UNESP]
dc.contributor.authorAmoroso, Lizandra [UNESP]
dc.contributor.authorMagalhães, Thaís Vendramini [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUNILAGO
dc.date.accessioned2023-07-29T13:42:37Z
dc.date.available2023-07-29T13:42:37Z
dc.date.issued2022-01-01
dc.description.abstractThe present study aimed to evaluate the influence of local administration of gentamicin or cephalothin on the healing of surgical wounds in dogs. Thirty healthy dogs were submitted to surgical castration. They were divided into 2 groups of 15 animals. After the surgical procedure, two 0.6 cm circular cutaneous wounds were made in the abdominal region. Group 1 received 0.1 ml of 0.9% saline in one wound and 0.1 ml of gentamicin (40 mg / ml) in the other wound; and group 2 received 0.1 ml of 0.9% saline and 0.1 ml of cephalothin (200 mg / ml); respectively. All wounds were sutured and assessed macroscopically 1, 3 and 10 days after the operation. On day 10, an incisional biopsy was performed for histopathological evaluation. All analyzes of macroscopic variables did not show significant differences between groups (P <0.05). There were no significant differences between groups for microscopic evaluation of collagenization, vascularization, edema and inflammatory cells (P <0.05). Thus, the topical use of the tested antibiotics does not influence skin healing in dogs.en
dc.description.affiliationDepartment of Clinical and Veterinary Surgery UNESP FCAV, SP
dc.description.affiliationDepartment of Veterinary Clinic and Surgery UNILAGO, SP
dc.description.affiliationDepartment of Morphology and Physiology UNESP FCAV, SP
dc.description.affiliationUnespDepartment of Clinical and Veterinary Surgery UNESP FCAV, SP
dc.description.affiliationUnespDepartment of Morphology and Physiology UNESP FCAV, SP
dc.format.extent346-350
dc.identifierhttp://dx.doi.org/10.21708/avb.2022.16.4.10689
dc.identifier.citationActa Veterinaria Brasilica, v. 16, n. 4, p. 346-350, 2022.
dc.identifier.doi10.21708/avb.2022.16.4.10689
dc.identifier.issn1981-5484
dc.identifier.scopus2-s2.0-85148430868
dc.identifier.urihttp://hdl.handle.net/11449/248388
dc.language.isoeng
dc.relation.ispartofActa Veterinaria Brasilica
dc.sourceScopus
dc.subjectAntibiotics
dc.subjectdog
dc.subjecthealing
dc.subjectwound
dc.titleTopical application of gentamicin or cephalothin in the healing of surgical wounds in dogsen
dc.titleAplicação tópica de gentamicina ou cefalotina na cicatrização de feridas cirúrgicas em cãespt
dc.typeArtigo

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Artigos - Clínica e Cirurgia Veterinária - FCAV
Artigos - Morfologia e Fisiologia Animal - FCAV