Chemical characterization and antimicrobial activity of hydroethanolic crude extract of Eugenia florida DC (Myrtaceae) leaves

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dc.contributor.authorBastos, Renan G.
dc.contributor.authorRosa, Carla P.
dc.contributor.authorOliver, Josidel C.
dc.contributor.authorSilva, Naiara C.
dc.contributor.authorDias, Amanda L. T.
dc.contributor.authorDa Rocha, Cláudia Q. [UNESP]
dc.contributor.authorVilegas, Wagner [UNESP]
dc.contributor.authorDa Silva, Geraldo A.
dc.contributor.authorDa Silva, Marcelo A.
dc.contributor.institutionUNIFAL-MG
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T17:28:22Z
dc.date.available2018-12-11T17:28:22Z
dc.date.issued2016-01-01
dc.description.abstractObjective: The present study aimed to characterize and quantify the total phenolics, flavonoids and tannins in a hydroethanolic crude extract (70% (v/v) (EB)) of the leaves of E. florida DC, as well as to evaluate the antimicrobial activity of the extract against different species of micro-organisms. Methods: EB was characterized using a mass spectrometer equipped with a direct insertion device for in-stream injection (FIA). Quantitative analyses of major compounds were carried out by spectrophotometry. In addition, we evaluated the sensitivity profiles of different strains of yeast and bacteria against different concentrations of EB. Results: The classes found were in agreement with those described in the literature: flavonoids, tannins, phenolic acids and saponins. EB showed levels of phenolic compounds, flavonoids and tannins equal to 25.82 mg gallic acid equivalents per gram of extract (EAG/g), 8.42 mg quercetin equivalents per gram of extract (EQ/g) and 7.30 mg tannic acid equivalents per gram of extract (AT/g), respectively. In the analysis of antimicrobial activity, EB was more active against yeasts but was not effective against the bacteria used in the test. Conclusion: We can conclude that E. florida DC has antimicrobial potential, due to the presence of bioactive secondary metabolites.en
dc.description.affiliationDepartment of Foods and Drugs Faculty of Pharmaceutical Sciences Laboratory of Medicinal Plants and Herbal Medicines Federal University of Alfenas UNIFAL-MG, Gabriel Monteiro da Silva Street, 700
dc.description.affiliationDepartament of Microbiology and Immunology Institute of Biomedical Sciences Laboratory of Research in Microbiology Federal University of Alfenas UNIFAL-MG, Gabriel Monteiro da Silva Street, 700
dc.description.affiliationInstitute of Biosciences Laboratory of Bioprospecting of Natural Products (LBPN) São Paulo State University UNESP, Coastal Campus-IB-CLP, Infante Dom Henrique Square, s/n°
dc.description.affiliationUnespInstitute of Biosciences Laboratory of Bioprospecting of Natural Products (LBPN) São Paulo State University UNESP, Coastal Campus-IB-CLP, Infante Dom Henrique Square, s/n°
dc.format.extent110-115
dc.identifier.citationInternational Journal of Pharmacy and Pharmaceutical Sciences, v. 8, n. 6, p. 110-115, 2016.
dc.identifier.issn0975-1491
dc.identifier.scopus2-s2.0-84971516400
dc.identifier.urihttp://hdl.handle.net/11449/178052
dc.language.isoeng
dc.relation.ispartofInternational Journal of Pharmacy and Pharmaceutical Sciences
dc.relation.ispartofsjr0,224
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectBacteria
dc.subjectMass spectrometer
dc.subjectMicro-organisms
dc.subjectPhenolics
dc.subjectPotential
dc.subjectYeasts
dc.titleChemical characterization and antimicrobial activity of hydroethanolic crude extract of Eugenia florida DC (Myrtaceae) leavesen
dc.typeArtigo

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