In vitro activity of Artemisia annua L (Asteraceae) extracts against Rhipicephalus (Boophilus) microplus

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dc.contributor.authorde Souza Chagas, Ana Carolina
dc.contributor.authorGeorgetti, Cynthia Sanches
dc.contributor.authorde Carvalho, Camila Olivo [UNESP]
dc.contributor.authorde Sena Oliveira, Márcia Cristina
dc.contributor.authorRodrigues, Rodney Alexandre
dc.contributor.authorFoglio, Mary Ann
dc.contributor.authorde Magalhãees, Pedro Melillo
dc.contributor.institutionEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
dc.contributor.institutionCentro Universitário Central Paulista - UNICEP
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.date.accessioned2022-04-28T18:56:45Z
dc.date.available2022-04-28T18:56:45Z
dc.date.issued2011-01-01
dc.description.abstractThe activity of plant extracts on parasites may indicate groups of substances that are potentially useful for controlling Rhipicephalus (Boophilus) microplus. The aim of the present study was to investigate the in vitro action of Artemisia annua extracts on this tick. The concentrations of the sesquiterpene lactones artemisinin and deoxyartemisinin present in plant extracts were quantified via high-performance liquid chromatography. Four extracts produced from the concentrated crude extract (CCE) were evaluated on larvae using the impregnated paper method, with readings after 24 hours of incubation. The engorged females were immersed in the CCE and in its four derived extracts for five minutes, with incubation for subsequent analysis of biological parameters. The extracts were not effective on the larvae at the concentrations tested (3.1 to 50 mg.mL-1). The CCE showed greater efficacy on engorged females (EC50 of 130.6 mg.mL-1 and EC90 of 302.9 mg.mL-1) than did the derived extracts. These results tend to confirm that the action of artemisinin on engorged females of R. (B.) microplus is conditional to their blood intake. In this case, in vitro methods would be inadequate for effective evaluation of the action of A. annua on R. (B.) microplus.en
dc.description.affiliationLaboratório de Sanidade Animal Embrapa Pecuária Sudeste Empresa Brasileira de Pesquisa Agropecuária - EMBRAPA
dc.description.affiliationCentro Universitário Central Paulista - UNICEP
dc.description.affiliationUniversidade Estadual Paulista - UNESP
dc.description.affiliationCentro Pluri-disciplinar de Pesquisas Químicas Biológicas e Agrícolas Universidade Estadual de Campinas - UNICAMP
dc.description.affiliationUnespUniversidade Estadual Paulista - UNESP
dc.format.extent31-35
dc.identifier.citationRevista Brasileira de Parasitologia Veterinaria, v. 20, n. 1, p. 31-35, 2011.
dc.identifier.issn0103-846X
dc.identifier.scopus2-s2.0-79955126045
dc.identifier.urihttp://hdl.handle.net/11449/219640
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Parasitologia Veterinaria
dc.sourceScopus
dc.subjectArtemisia annua
dc.subjectArtemisinin
dc.subjectControl
dc.subjectPhytotherapy
dc.subjectR. (B.) microplus
dc.subjectTick
dc.titleIn vitro activity of Artemisia annua L (Asteraceae) extracts against Rhipicephalus (Boophilus) microplusen
dc.titleAtividade in vitro de extratos de Artemisia annua L (Asteraceae) sobre Rhipicephalus (Boophilus) micropluspt
dc.typeArtigo

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