Exercise as a peripheral circadian clock resynchronizer in vascular and skeletal muscle aging

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dc.contributor.authorde Alencar Silva, Bruna Spolador [UNESP]
dc.contributor.authorUzeloto, Juliana Souza [UNESP]
dc.contributor.authorLira, Fábio Santos [UNESP]
dc.contributor.authorPereira, Telmo
dc.contributor.authorCoelho-E-silva, Manuel J.
dc.contributor.authorCaseiro, Armando
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionPolytechnic Institute of Coimbra
dc.contributor.institutionLaboratory for Applied Health Research (LabinSaúde)
dc.contributor.institutionUniversity of Coimbra
dc.contributor.institutionUniversidade de Coimbra
dc.date.accessioned2022-04-28T19:47:54Z
dc.date.available2022-04-28T19:47:54Z
dc.date.issued2021-12-01
dc.description.abstractAging is characterized by several progressive physiological changes, including changes in the circadian rhythm. Circadian rhythms influence behavior, physiology, and metabolic processes in order to maintain homeostasis; they also influence the function of endothelial cells, smooth muscle cells, and immune cells in the vessel wall. A clock misalignment could favor vascular damage and indirectly also affect skeletal muscle function. In this review, we focus on the dysregulation of circadian rhythm due to aging and its relationship with skeletal muscle changes and vascular health as possible risk factors for the development of sarcopenia, as well as the role of physical exercise as a potential modulator of these processes.en
dc.description.affiliationExercise and Immunometabolism Research Group Universidade Estadual Paulista (UNESP)
dc.description.affiliationClinical Physiology Coimbra Health School Polytechnic Institute of Coimbra, Rua 5 de Outubro—SM Bispo, Apartado 7006
dc.description.affiliationLaboratory for Applied Health Research (LabinSaúde), Rua 5 de Outubro—SM Bispo, Apartado 7006
dc.description.affiliationFaculty of Sport Science and Physical Education University of Coimbra
dc.description.affiliationUnidade I&D Química-Física Molecular Faculdade de Ciências e Tecnologia Universidade de Coimbra
dc.description.affiliationBiomedical Laboratory Sciences Coimbra Health School Polytechnic Institute of Coimbra, Rua 5 de Outubro—SM Bispo, Apartado 7006
dc.description.affiliationUnespExercise and Immunometabolism Research Group Universidade Estadual Paulista (UNESP)
dc.identifierhttp://dx.doi.org/10.3390/ijerph182412949
dc.identifier.citationInternational Journal of Environmental Research and Public Health, v. 18, n. 24, 2021.
dc.identifier.doi10.3390/ijerph182412949
dc.identifier.issn1660-4601
dc.identifier.issn1661-7827
dc.identifier.scopus2-s2.0-85120676483
dc.identifier.urihttp://hdl.handle.net/11449/222991
dc.language.isoeng
dc.relation.ispartofInternational Journal of Environmental Research and Public Health
dc.sourceScopus
dc.subjectCircadian rhythms
dc.subjectClock genes
dc.subjectInflammation
dc.subjectSarcopenia
dc.subjectSkeletal muscle disfunction
dc.subjectVascular disfunction
dc.titleExercise as a peripheral circadian clock resynchronizer in vascular and skeletal muscle agingen
dc.typeResenha

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