Applicability of the drainage effectiveness of Blake drains and Tenckhoff catheters in the peritoneal dialysis of healthy rabbits (Oryctolagus cuniculus)

dc.contributor.authorPereira, Ana Camila [UNESP]
dc.contributor.authorGeraldes, Silvano S. [UNESP]
dc.contributor.authorMaia, Suellen R. [UNESP]
dc.contributor.authorde Azevedo, Maria Gabriela P. [UNESP]
dc.contributor.authorda Silva, Gustavo G. [UNESP]
dc.contributor.authorde Souza, Bruna N. [UNESP]
dc.contributor.authorGarcía, Henry David M. [UNESP]
dc.contributor.authorMelchert, Alessandra [UNESP]
dc.contributor.authorBrandão, Cláudia Valéria S. [UNESP]
dc.contributor.authorde Souza, Fabiana F. [UNESP]
dc.contributor.authorGuimarães-Okamoto, Priscylla T. C. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2023-07-29T13:22:29Z
dc.date.available2023-07-29T13:22:29Z
dc.date.issued2022-11-01
dc.description.abstractObjective: To compare the efficacy of dialysate drainage between Tenckhoff (TC) catheter and Blake (BL) in peritoneal dialysis (PD) in healthy rabbits. Design: Prospective experimental study. Setting: University Teaching Hospital and University research laboratory. Animals: Twenty healthy, male, New Zealand rabbits. Interventions: PD via the TC catheter and the BL abdominal drain was compared during 3 consecutive days of dialysis delivery. Measurements and Main Results: One session of PD was performed per day for 3 consecutive days (S1: first session, S2: second session, S3: third session) and each session included 4 cycles of infusion, dwell of dialysate in the abdomen, and drainage. Data collection included daily urea, creatinine, alanine aminotransferase, albumin, and potassium, in addition to hematological parameters (eg, RBC, HCT, hemoglobin, WBC, and platelet count). Statistical analysis using a mixed linear model with multiple comparisons was performed. The BL drain resulted in an increase in volume drained (ml/kg) when compared to TC catheter on S2 (third and fourth cycles) and S3 (first and second cycles). Conclusions: The BL drain proved to be superior to the TC catheter, being capable of draining a larger volume of dialysate during the drainage processes in the peritoneal PD of healthy rabbits. The TC catheter had major complications with regard to fluid retention in the abdomen, representing reduced drainage efficiency, while the BL drain showed a greater tendency for the peritoneal fluid to leak.en
dc.description.affiliationDepartment of Veterinary Clinics School of Veterinary Medicine and Animal Science São Paulo State University - UNESP
dc.description.affiliationDepartment of Veterinary Surgery School of Veterinary Medicine and Animal Science São Paulo State University - UNESP
dc.description.affiliationUnespDepartment of Veterinary Clinics School of Veterinary Medicine and Animal Science São Paulo State University - UNESP
dc.description.affiliationUnespDepartment of Veterinary Surgery School of Veterinary Medicine and Animal Science São Paulo State University - UNESP
dc.format.extent748-755
dc.identifierhttp://dx.doi.org/10.1111/vec.13252
dc.identifier.citationJournal of Veterinary Emergency and Critical Care, v. 32, n. 6, p. 748-755, 2022.
dc.identifier.doi10.1111/vec.13252
dc.identifier.issn1476-4431
dc.identifier.issn1479-3261
dc.identifier.scopus2-s2.0-85138719720
dc.identifier.urihttp://hdl.handle.net/11449/247666
dc.language.isoeng
dc.relation.ispartofJournal of Veterinary Emergency and Critical Care
dc.sourceScopus
dc.subjectdialysis treatment
dc.subjectkidney injury
dc.subjectperitoneum
dc.subjecturemic toxins
dc.titleApplicability of the drainage effectiveness of Blake drains and Tenckhoff catheters in the peritoneal dialysis of healthy rabbits (Oryctolagus cuniculus)en
dc.typeArtigo
unesp.author.orcid0000-0001-7495-0867[1]
unesp.author.orcid0000-0003-1944-2426[11]

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