Effect of the consumption of a new symbiotic shake on glycemia and cholesterol levels in elderly people with type 2 diabetes mellitus

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dc.contributor.authorMoroti, Camila [UNESP]
dc.contributor.authorSouza Magri, Loyanne Francine [UNESP]
dc.contributor.authorCosta, Marcela de Rezende [UNESP]
dc.contributor.authorCavallini, Daniela Cardoso Umbelino [UNESP]
dc.contributor.authorSivieri, Katia [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniv Estadual
dc.date.accessioned2014-05-20T13:23:43Z
dc.date.available2014-05-20T13:23:43Z
dc.date.issued2012-02-22
dc.description.abstractBackground: The consumption of foods containing probiotic and prebiotic ingredients is growing consistently every year, and in view of the limited number of studies investigating their effect in the elderly.Objective: The objective of this study was to evaluate the effect of the consumption of a symbiotic shake containing Lactobacillus acidophilus, Bifidobacterium bifidum and fructooligosaccharides on glycemia and cholesterol levels in elderly people.Methods: A randomized, double-blind, placebo-controlled study was conducted on twenty volunteers (ten for placebo group and ten for symbiotic group), aged 50 to 60 years. The criteria for inclusion in the study were: total cholesterol > 200 mg/dL; triglycerides > 200 mg/dL and glycemia > 110 mg/dL. Over a total test period of 30 days, 10 individuals (the symbiotic group) consumed a daily dose of 200 mL of a symbiotic shake containing 10(8) UFC/mL Lactobacillus acidophilus, 10(8) UFC/mL Bifidobacterium bifidum and 2 g oligofructose, while 10 other volunteers (the placebo group) drank daily the same amount of a shake that did not contain any symbiotic bacteria. Blood samples were collected 15 days prior to the start of the experiment and at 10-day intervals after the beginning of the shake intake. The standard lipid profile (total cholesterol, triglycerides and HDL cholesterol) and glycemia, or blood sugar levels, were evaluated by an enzyme colorimetric assay.Results: The results of the symbiotic group showed a non-significant reduction (P > 0.05) in total cholesterol and triglycerides, a significant increase (P < 0.05) in HDL cholesterol and a significant reduction (P < 0.05) in fasting glycemia. No significant changes were observed in the placebo group.Conclusion: The consumption of symbiotic shake resulted in a significant increase in HDL and a significant decrease of glycemia.en
dc.description.affiliationSão Paulo State Univ, Sch Pharmaceut Sci, Dept Food & Nutr, Araraquara, SP, Brazil
dc.description.affiliationUniv Estadual, Fac Ciencias Farmaceut, Dept Alimentos & Nutr, BR-14802901 Araraquara, SP, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Sch Pharmaceut Sci, Dept Food & Nutr, Araraquara, SP, Brazil
dc.format.extent8
dc.identifierhttp://dx.doi.org/10.1186/1476-511X-11-29
dc.identifier.citationLipids In Health and Disease. London: Biomed Central Ltd., v. 11, p. 8, 2012.
dc.identifier.doi10.1186/1476-511X-11-29
dc.identifier.fileWOS000301590800001.pdf
dc.identifier.issn1476-511X
dc.identifier.urihttp://hdl.handle.net/11449/7208
dc.identifier.wosWOS:000301590800001
dc.language.isoeng
dc.publisherBiomed Central Ltd.
dc.relation.ispartofLipids in Health and Disease
dc.relation.ispartofjcr2.663
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectBifidobacterium bifidumen
dc.subjectFructooligosaccharideen
dc.subjectLactobacillus acidophilusen
dc.subjectSymbioticsen
dc.subjectShakeen
dc.titleEffect of the consumption of a new symbiotic shake on glycemia and cholesterol levels in elderly people with type 2 diabetes mellitusen
dc.typeArtigo
dcterms.licensehttp://www.biomedcentral.com/about/license
dcterms.rightsHolderBiomed Central Ltd.
unesp.author.orcid0000-0001-8632-1478[5]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentAlimentos e Nutrição - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas