Doxycycline hyclate: a review of properties, applications and analytical methods

Página do item simplificado
dc.contributor.authorKogawa, Ana Carolina [UNESP]
dc.contributor.authorSalgado, Hérida Regina Nunes
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2016-01-28T16:56:38Z
dc.date.available2016-01-28T16:56:38Z
dc.date.issued2012
dc.description.abstractThe doxycycline hyclate is a broad-spectrum antibiotic oxytetracycline synthetic derivative used in several countries. It has been used to treat infectious diseases and as an additive in animal nutrition to facilitate growth. This drug is part of the list of medicines to the SUS (Unified Health System), a model of health care in Brazil, and it is free delivery in the public with a medical prescription. Thus, it is extremely important quality control of this medicine to be able to ensure their effectiveness and safety. Several existing analytical techniques, which offer flexible and broad-based methods of analysis and in some cases detection, have been discussed in this manuscript, focusing on bioanalytical and pharmaceutical quality control applications. This review will examine the published analytical methods reported for determination of doxycycline hyclate, discussing (a) separation methods such as thin layer chromatography and high performance liquid chromatography (HPLC) and (b) others such as, spectrophotometry and microbiological assay, from which it can be seen that HPLC methods have been used most extensively.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Farmacos e Médicamentos, Faculdade de Ciências Farmacêuticas de Araraquara, Araraquara, Rodovia Araraquara-Jaú, km1, Campus, CEP 14801-902, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Farmacos e Médicamentos, Faculdade de Ciências Farmacêuticas de Araraquara, Araraquara, Rodovia Araraquara-Jaú, km1, Campus, CEP 14801-902, SP, Brasil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent11-18
dc.identifierhttp://www.ijlpr.com/admin/php/uploads/152_pdf.pdf
dc.identifier.citationInternational Journal of Life Science and Pharma Research, v. 2, n. 4, p. 11-18, 2012.
dc.identifier.issn2250-0480
dc.identifier.lattes6638857912920334
dc.identifier.lattes9881720291571774
dc.identifier.urihttp://hdl.handle.net/11449/133794
dc.language.isoeng
dc.relation.ispartofInternational Journal of Life Science and Pharma Research
dc.rights.accessRightsAcesso restrito
dc.sourceCurrículo Lattes
dc.subjectDoxycycline hyclateen
dc.subjectAnalytical methodsen
dc.subjectQuality controlen
dc.titleDoxycycline hyclate: a review of properties, applications and analytical methodsen
dc.typeArtigo
unesp.author.lattes6638857912920334
unesp.author.lattes9881720291571774
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentFármacos e Medicamentos - FCFpt

Arquivos

Coleções

Araraquara - FCF - Faculdade de Ciências Farmacêuticas