Evaluating the performance of the PRISMA-7 frailty criteria for predicting disability and death after acute ischemic stroke: PRISMA-7 - Disability or Death after Stroke

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dc.contributor.authorMiranda, Luana Aparecida [UNESP]
dc.contributor.authorLuvizutto, Gustavo José
dc.contributor.authorStephan, Blossom Christa Maree
dc.contributor.authorSouza, Juli Thomaz de [UNESP]
dc.contributor.authorSilva, Taís Regina da [UNESP]
dc.contributor.authorWinckler, Fernanda Cristina [UNESP]
dc.contributor.authorFerreira, Natalia Cristina [UNESP]
dc.contributor.authorAntunes, Leticia Claudia de Oliveira [UNESP]
dc.contributor.authorBessornia, Pedro Augusto Cândido [UNESP]
dc.contributor.authorBazan, Silméia Garcia Zanati [UNESP]
dc.contributor.authorFukushima, Fernanda Bono [UNESP]
dc.contributor.authorCosta, Rafael Dalle Molle da [UNESP]
dc.contributor.authorModolo, Gabriel Pinheiro [UNESP]
dc.contributor.authorMinicucci, Marcos Ferreira [UNESP]
dc.contributor.authorBazan, Rodrigo [UNESP]
dc.contributor.authorVidal, Edison Iglesias de Oliveira [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionFederal University of Triângulo Mineiro (UFTM)
dc.contributor.institutionUniversity of Nottingham Medical School
dc.date.accessioned2023-07-29T13:25:40Z
dc.date.available2023-07-29T13:25:40Z
dc.date.issued2022-12-01
dc.description.abstractObjectives: We aimed to evaluate the predictive performance of the PRISMA-7 frailty criteria regarding the composite outcome of disability or death in patients with an acute ischemic stroke, and to compare it with the Frailty Index and the National Institutes of Health Stroke Scale (NIHSS). Materials and methods: This prospective cohort study involved all patients aged ≥ 40 years admitted with an acute ischemic stroke between March 2019 and January 2020. We performed survival analyses, calculated risk ratios, sensitivity, specificity, and predictive values for the combined outcome of disability or death according to the presence of frailty as determined by the PRISMA-7 and the Frailty Index, and stroke severity based on the NIHSS. Results: In 174 patients with acute ischemic stroke, being frail in the week before the stroke according to the PRISMA-7 was associated with a Risk Ratio of 4·50 (95%CI 1·77-11·43, P <0·001) and a Positive Predictive Value of 89% (95%CI 77-99%) for being disabled or dead 90 days after the stroke, and a Hazard Ratio of 3·33 (95%CI 1·48-7·51, P = 0·004) for the survival outcome. The predictive performance of the PRISMA-7 was not significantly different from the Frailty Index or the NIHSS. Conclusions: We provide evidence that the PRISMA-7 frailty criteria may be a useful prognostication tool in acute ischemic stroke.en
dc.description.affiliationDepartment of Internal Medicine Botucatu Medical School Sao Paulo State University (UNESP)
dc.description.affiliationDepartment of Applied Physical Therapy Federal University of Triângulo Mineiro (UFTM)
dc.description.affiliationInstitute of Mental Health University of Nottingham Medical School
dc.description.affiliationDepartment of Rehabilitation Botucatu Medical School Sao Paulo State University (UNESP)
dc.description.affiliationDepartment of Surgical Specialties and Anesthesiology Botucatu Medical School Sao Paulo State University (UNESP)
dc.description.affiliationDepartment of Neurology Psychology and Psychiatry Botucatu Medical School Sao Paulo State University (UNESP)
dc.description.affiliationUnespDepartment of Internal Medicine Botucatu Medical School Sao Paulo State University (UNESP)
dc.description.affiliationUnespDepartment of Rehabilitation Botucatu Medical School Sao Paulo State University (UNESP)
dc.description.affiliationUnespDepartment of Surgical Specialties and Anesthesiology Botucatu Medical School Sao Paulo State University (UNESP)
dc.description.affiliationUnespDepartment of Neurology Psychology and Psychiatry Botucatu Medical School Sao Paulo State University (UNESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.identifierhttp://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106837
dc.identifier.citationJournal of Stroke and Cerebrovascular Diseases, v. 31, n. 12, 2022.
dc.identifier.doi10.1016/j.jstrokecerebrovasdis.2022.106837
dc.identifier.issn1532-8511
dc.identifier.issn1052-3057
dc.identifier.scopus2-s2.0-85140332801
dc.identifier.urihttp://hdl.handle.net/11449/247779
dc.language.isoeng
dc.relation.ispartofJournal of Stroke and Cerebrovascular Diseases
dc.sourceScopus
dc.subjectFrailty
dc.subjectFunctional status
dc.subjectIschemic stroke
dc.subjectPrognosis
dc.subjectSurvival
dc.titleEvaluating the performance of the PRISMA-7 frailty criteria for predicting disability and death after acute ischemic stroke: PRISMA-7 - Disability or Death after Strokeen
dc.typeArtigo
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentAnestesiologia - FMBpt
unesp.departmentClínica Médica - FMBpt
unesp.departmentNeurologia, Psicologia e Psiquiatria - FMBpt

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Botucatu - FMB - Faculdade de Medicina